Patents by Inventor Heinz Gulle
Heinz Gulle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230210958Abstract: Disclosed are a fibrinogen solution and a thrombin solution. The fibrinogen solution comprises fibrinogen at a concentration of at least 40 mg/ml, factor XIII, pharmaceutically acceptable additives and water. The dynamic viscosity of the fibrinogen solution measured at 20° C. increases at most by 35% after storing the solution at 20° C. for 30 days. The thrombin solution comprises thrombin, pharmaceutically acceptable additives and water. The thrombin activity decreases at most by 15% after storing the solution at 25° C. for 14 days. Also disclosed is a fibrin sealant kit with a first container comprising the fibrinogen solution and a second container comprising the thrombin solution. Further, methods for preparing a fibrin sealant and methods for treating a wound are disclosed.Type: ApplicationFiled: December 9, 2022Publication date: July 6, 2023Inventors: Heinz Gulle, Rahul Kumar Singh, Julia Rabas, Eva Reinauer, Stella Grosso
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Patent number: 10322170Abstract: The invention discloses a hemostatic composition comprising: a) a biocompatible polymer in particulate form suitable for use in hemostasis, and b) one hydrophilic polymeric component comprising reactive groups.Type: GrantFiled: March 24, 2016Date of Patent: June 18, 2019Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Heinz Gulle, Joris Hoefinghoff, Andreas Goessl, Katarzyna Gorna
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Patent number: 9724449Abstract: The present invention relates to a biodegradable injectable composition for bone augmentation comprising fibrin, a contrast agent and calcium salt-containing particles, as well as a method for bone augmentation in a patient suffering from a bone disorder comprising injecting said composition into a non-mineralized or hollow portion of said bone.Type: GrantFiled: August 17, 2015Date of Patent: August 8, 2017Assignees: Baxter International Inc., Baxter Healthcare, S.A.Inventors: John J. Barry, Andreas Goessl, Heinz Gulle, Monika Mangold, Melitta Bilban
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Patent number: 9512277Abstract: Bone hemostat compositions, and methods for their use and manufacture are provided. Exemplary hemostatic compositions include polymeric components such as random and non-random copolymers, natural polymers, ceramics, reactive group polymers, and combinations thereof. Bone compositions may be used during surgical procedures, and may be applied to bone to inhibit or prevent bleeding from bone.Type: GrantFiled: October 29, 2012Date of Patent: December 6, 2016Assignees: Baxter International, Inc., Baxter Healthcare, S.A.Inventors: Katarzyna I. Gorna, Andreas Goessl, Heinz Gulle
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Publication number: 20160271228Abstract: The invention discloses a hemostatic composition comprising: a) a biocompatible polymer in particulate form suitable for use in hemostasis, and b) one hydrophilic polymeric component comprising reactive groups.Type: ApplicationFiled: March 24, 2016Publication date: September 22, 2016Inventors: Heinz Gulle, Joris Hoefinghoff, Andreas Goessl, Katarzyna Gorna
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Patent number: 9421302Abstract: The present invention relates to a biodegradable injectable composition for bone augmentation comprising fibrin, a contrast agent and calcium salt-containing particles, as well as a method for bone augmentation in a patient suffering from a bone disorder comprising injecting said composition into a non-mineralized or hollow portion of said bone.Type: GrantFiled: April 17, 2007Date of Patent: August 23, 2016Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: John J. Barry, Andreas Goessl, Heinz Gulle, Monika Mangold, Melitta Bilban
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Patent number: 9278160Abstract: The present invention teaches a micro-porous injectable, soft elastic, fully resorbable fibrin-based composition for use as a soft tissue lumen and void filler. The composition of the present application exhibits physical characteristics, such as mechanical properties, typically seen in elastomers and mechanical stability, which is superior to fibrin alone. A variety of properties of the composition of the present invention can be effectively fine-tuned and altered by adjusting type and content of the particles as well as of the plasticizer contained in the void filler composition.Type: GrantFiled: January 10, 2013Date of Patent: March 8, 2016Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: John J. Barry, Andreas Goessl, Heinz Gulle, Monika Mangold, Melitta Bilban
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Patent number: 9248215Abstract: The present invention relates to a biodegradable fibrin based composition for injection into osseous defects or voids, which can be the result of osteoporosis, surgery, bone cysts, tumor removal or traumatic bone injury.Type: GrantFiled: April 17, 2007Date of Patent: February 2, 2016Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: John J. Barry, Andreas Goessl, Heinz Gulle, Monika Mangold, Melitta Bilban
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Publication number: 20150352253Abstract: The present invention relates to a biodegradable injectable composition for bone augmentation comprising fibrin, a contrast agent and calcium salt-containing particles, as well as a method for bone augmentation in a patient suffering from a bone disorder comprising injecting said composition into a non-mineralized or hollow portion of said bone.Type: ApplicationFiled: August 17, 2015Publication date: December 10, 2015Inventors: John J. Barry, Andreas Goessl, Heinz Gulle, Monika Mangold, Melitta Bilban
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Publication number: 20130287818Abstract: Bone hemostat compositions, and methods for their use and manufacture are provided. Exemplary hemostatic compositions include polymeric components such as random and non-random copolymers, natural polymers, ceramics, reactive group polymers, and combinations thereof. Bone compositions may be used during surgical procedures, and may be applied to bone to inhibit or prevent bleeding from bone.Type: ApplicationFiled: October 29, 2012Publication date: October 31, 2013Inventors: Katarzyna I. Gorna, Andreas Goessl, Heinz Gulle
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Patent number: 8377420Abstract: The present invention teaches a micro-porous injectable, soft elastic, fully resorbable fibrin-based composition for use as a soft tissue lumen and void filler. The composition of the present application exhibits physical characteristics, such as mechanical properties, typically seen in elastomers and mechanical stability, which is superior to fibrin alone. A variety of properties of the composition of the present invention can be effectively fine-tuned and altered by adjusting type and content of the particles as well as of the plasticizer contained in the void filler composition.Type: GrantFiled: January 11, 2011Date of Patent: February 19, 2013Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: John J. Barry, Andreas Goessl, Heinz Gulle, Monika Mangold, Melitta Bilban
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Publication number: 20110117027Abstract: The present invention teaches a micro-porous injectable, soft elastic, fully resorbable fibrin-based composition for use as a soft tissue lumen and void filler. The composition of the present application exhibits physical characteristics, such as mechanical properties, typically seen in elastomers and mechanical stability, which is superior to fibrin alone. A variety of properties of the composition of the present invention can be effectively fine-tuned and altered by adjusting type and content of the particles as well as of the plasticizer contained in the void filler composition.Type: ApplicationFiled: January 11, 2011Publication date: May 19, 2011Applicants: Baxter Healthcare S.A., Baxter International Inc.Inventors: John J. Barry, Andreas Goessl, Heinz Gulle, Monika Mangold, Melitta Bilban
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Publication number: 20080241072Abstract: The present invention teaches a micro-porous injectable, soft elastic, fully resorbable fibrin-based composition for use as a soft tissue lumen and void filler. The composition of the present application exhibits physical characteristics, such as mechanical properties, typically seen in elastomers and mechanical stability, which is superior to fibrin alone. A variety of properties of the composition of the present invention can be effectively fine-tuned and altered by adjusting type and content of the particles as well as of the plasticizer contained in the void filler composition.Type: ApplicationFiled: March 25, 2008Publication date: October 2, 2008Applicants: Baxter International Inc., Baxter Healthcare S.A.Inventors: John J. Barry, Andreas Goessl, Heinz Gulle, Monika Mangold, Melitta Bilban
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Publication number: 20070275028Abstract: The present invention relates to a biodegradable injectable composition for bone augmentation comprising fibrin, a contrast agent and calcium salt-containing particles, as well as a method for bone augmentation in a patient suffering from a bone disorder comprising injecting said composition into a non-mineralized or hollow portion of said bone.Type: ApplicationFiled: April 17, 2007Publication date: November 29, 2007Applicants: Baxter International Inc., Baxter Healthcare, S.A.Inventors: John Barry, Andreas Goessl, Heinz Gulle, Monika Mangold, Melitta Bilban
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Publication number: 20070276505Abstract: The present invention relates to a biodegradable fibrin based composition for injection into osseous defects or voids, which can be the result of osteoporosis, surgery, bone cysts, tumor removal or traumatic bone injury.Type: ApplicationFiled: April 17, 2007Publication date: November 29, 2007Applicants: Baxter International Inc., Baxter Healthcare, S.A.Inventors: John Barry, Andreas Goessl, Heinz Gulle, Monika Mangold, Melitta Bilban