Patents by Inventor Helen McGettrick

Helen McGettrick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BONE DISEASE TREATMENT
    Publication number: 20240131110
    Abstract: The present invention concerns methods of reducing bone loss and/or stimulating bone production comprising administering an effective amount of a peptide comprising the amino acid sequence SVTEQGAELSNEER (SEQ ID NO:1), or variants thereof, to a patient and/or bone cells. The present invention also concerns methods of treatment and/or prophylaxis of musculoskeletal loss and/or damage in a patient, comprising administering an effective amount of the peptide.
    Type: Application
    Filed: October 16, 2023
    Publication date: April 25, 2024
    Inventors: George Edward Rainger, Helen McGettrick, Myriam Chimen
  • BONE DISEASE TREATMENT
    Publication number: 20210100870
    Abstract: The present invention concerns methods of reducing bone loss and/or stimulating bone production comprising administering an effective amount of a peptide comprising the amino acid sequence SVTEQGAELSNEER (SEQ ID NO:1), or variants thereof, to a patient and/or bone cells. The present invention also concerns methods of treatment and/or prophylaxis of musculoskeletal loss and/or damage in a patient, comprising administering an effective amount of the peptide.
    Type: Application
    Filed: October 8, 2020
    Publication date: April 8, 2021
    Inventors: George Edward Rainger, Helen McGettrick, Myriam Chimen
  • Peptide and uses therefor
    Patent number: 9839671
    Abstract: Provided is a method for treatment and/or prophylaxis of a condition associated with T cell mediated chronic inflammatory disease by administration, to a patient, of a peptide comprising N?-SVTEQGAELSNEER-C? (SEQ ID NO: 1) or an analog thereof that inhibits T cell migration. Also provided is the peptide or its analog for use in the methods of treatment and/or prophylaxis of said condition. Also provided is a method for the treatment of Sjogren's syndrome by administration of a peptide comprising N?-SVTEQGAELSNEER-C? to a patient in need thereof.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: December 12, 2017
    Assignee: The University of Birmingham
    Inventors: George Edward Rainger, Parth Narendran, Helen McGettrick, Myriam Chimen
  • PEPTIDE AND USES THEREFOR
    Publication number: 20170151309
    Abstract: Provided is a method for treatment and/or prophylaxis of a condition associated with T cell mediated chronic inflammatory disease by administration, to a patient, of a peptide comprising N?-SVTEQGAELSNEER-C? (SEQ ID NO: 1) or an analogue thereof that inhibits T cell migration. Also provided is the peptide or its analogue for use in the methods of treatment and/or prophylaxis of said condition. Also provided is a method for the treatment of Sjogren's syndrome by administration of a peptide comprising N?-SVTEQGAELSNEER-C? to a patient in need thereof.
    Type: Application
    Filed: November 17, 2016
    Publication date: June 1, 2017
    Applicant: University of Birmingham
    Inventors: George Edward Rainger, Parth Narendran, Helen McGettrick, Myriam Chimen
  • Peptide and uses therefor
    Patent number: 9597368
    Abstract: Provided is a method for treatment and/or prophylaxis of a condition associated with T cell mediated chronic inflammatory disease by administration, to a patient, of a peptide comprising N?-SVTEQGAELSNEER-C? (SEQ ID NO: 1) or an analog of the peptide that inhibits T cell migration. Also provided is the peptide or its analog for use in the methods of treatment and/or prophylaxis of the condition.
    Type: Grant
    Filed: January 14, 2013
    Date of Patent: March 21, 2017
    Assignee: The University of Birmingham
    Inventors: George Edward Rainger, Parth Narendran, Helen McGettrick, Myriam Chimen
  • CADHERIN 15 AGONISTS
    Publication number: 20160152704
    Abstract: CDH15 has been identified as a receptor for a peptide which has an inhibitory effect of the migration of T cells. Agonists of this receptor have applications in the treatment and/or prophylaxis of conditions associated with the migration of T-cells, including T cell auto-reactivity, T cell mediated chronic inflammatory disease and autoimmune disease. The agonist is not PEPITEM or an analogue thereof.
    Type: Application
    Filed: July 4, 2014
    Publication date: June 2, 2016
    Applicant: The University of Birmingham
    Inventors: Myriam Chimen, Helen Mcgettrick, Parth Narendran, George Edward Rainger
  • PEPTIDE AND USES THEREFOR
    Publication number: 20150051137
    Abstract: Provided is a method for treatment and/or prophylaxis of a condition associated with T cell mediated chronic inflammatory disease by administration, to a patient, of a peptide comprising N?-SVTEQGAELSNEER-C? {SEQ ID NO: 1) or an analogue thereof that inhibits T cell migration. Also provided is the peptide or its analogue for use in the methods of treatment: and/or prophylaxis of said condition.
    Type: Application
    Filed: January 14, 2013
    Publication date: February 19, 2015
    Applicant: The University of Birmingham
    Inventors: George Edward Rainger, Parth Narendran, Helen McGettrick, Myriam Chimen