Abstract: A composition comprises: a base oil; an additive; and a drug. The additive has segments which are conjugated, e.g. covalently linked, together. A first segment facilitates solubility in the base oil, whereas a second segment facilitates drug solubility and/or modifies drug release or other behaviour. The first segment may for example comprise a poly(dimethylsiloxane)-containing moiety. The second segment may for example resemble a drug molecule. The composition may for example be used as a tamponade or as a component for a tamponade administered to the eye.

Abstract: A micro puree machine includes a mixing shaft coupled to a blade and rotatable by means of a gear. A magnet is coupled to the gear and a rotation sensor is mounted on the machine housing. As the mixing shaft descends into the pre-frozen ingredients, the rotation sensor detects a magnetic field of the magnet as the gear rotates and generates a rotation signal in response. A controller receives the rotation signal and determines a rotation count associated with the gear, causing the mixing shaft to ascend back toward the housing once a pre-selected rotation count has been reached. The pre-selected rotation count correlates with the partial processing of the ingredients.

Abstract: A lid and blade assembly for a micro puree machine includes a lid having a central aperture for receiving a central hub of the blade. At least two cutting arms and at least two mixing arms extend radially outward from the central hub. A retaining component retains the blade within the lid during processing. The lid includes a recess below the retaining component for collecting slush and ice displaced by the blade during processing. Portions of the blade also include serrated grooves for clearing slush deposits when the blade engages the lid.

Abstract: A lid and blade assembly for a micro puree machine includes a lid having a central aperture for receiving a central hub of the blade. At least two cutting arms and at least two mixing arms extend radially outward from the central hub. A retaining component retains the blade within the lid during processing. The lid includes a recess below the retaining component for collecting slush and ice displaced by the blade during processing. Portions of the blade also include serrated grooves for clearing slush deposits when the blade engages the lid.

Abstract: A micro puree machine includes a mixing shaft coupled to a blade and rotatable by means of a gear. A magnet is coupled to the gear and a rotation sensor is mounted on the machine housing. As the mixing shaft descends into the pre-frozen ingredients, the rotation sensor detects a magnetic field of the magnet as the gear rotates and generates a rotation signal in response. A controller receives the rotation signal and determines a rotation count associated with the gear, causing the mixing shaft to ascend back toward the housing once a pre-selected rotation count has been reached. The pre-selected rotation count correlates with the partial processing of the ingredients.

Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.

Abstract: Aspects of the subject disclosure may include, for example, a system for obtaining sensor data associated with a plurality of body parts of a monitored individual, measuring from the sensor data a positioning of the plurality of body parts of the monitored individual, comparing the positioning of the plurality of body parts to a target positioning of the plurality of body parts, detecting from the comparing a deficiency in a use of the plurality of body parts, and generating a message associated with the deficiency. Other embodiments are disclosed.

Abstract: In the production of micron-size pyramid emitters for field emission devices, a first layer of electrically-conductive material, such as single crystal silicon or metal, is etched to form column-like structures each of which tapers from each end of the column towards an intermediate portion along its length. A second conductive layer is formed in contact with the free ends of the columns, and etching of the columns is then resumed until the intermediate portion of each column is etched through, leaving a pair of pyramid emitters pointing towards one another and supported by the respective conductive layer.

Abstract: In the production of micron-size pyramid emitters for field emission devices, very sharp emitter points are achieved by providing a layer of suitable metal, metal compound or semiconductor, forming masking pads over the required emitter positions, etching the layer so that column-like structures are formed beneath the pads, removing the pads, and then subjecting the columns to dry etching, such as plasma etching, reactive ion etching, ion beam milling or reactive ion beam milling. The dry etching process shapes the columns into pyramids with a tip size of the order of 0.03 microns.