Patents by Inventor Helena Kelly

Helena Kelly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERMO-RESPONSIVE HYDROGEL FOR INTRATUMORAL ADMINISTRATION AS A TREATMENT IN SOLID TUMOR CANCERS
    Publication number: 20230126053
    Abstract: A room temperature injectable thermo-responsive hydrogel comprises a P407 poloxamer base hydrogel, chitosan, 2-Hydroxypropyl ?-cyclodextrin and genipin. The chitosan and genipin form an interpenetrating scaffold within the hydrogel in which the chitosan is crosslinked with genipin. Chemotherapeutic drugs can be added to the hydrogel singly or in combination in effective amounts without any loss of thermo-responsiveness in the hydrogel. Therapeutic use of the thermo-responsive hydrogel in the intratumoural treatment of solid cancer is also described.
    Type: Application
    Filed: November 2, 2022
    Publication date: April 27, 2023
    Inventors: Helena Kelly, Garry Duffy, Seona Rossi, Conn Hastings
  • Thermo-responsive hydrogel for intratumoral administration as a treatment in solid tumor cancers
    Patent number: 11534401
    Abstract: A room temperature injectable thermo-responsive hydrogel comprises a P407 poloxamer base hydrogel, chitosan, 2-Hydroxypropyl ?-cyclodextrin and genipin. The chitosan and genipin form an interpenetrating scaffold within the hydrogel in which the chitosan is crosslinked with genipin. Chemotherapeutic drugs can be added to the hydrogel singly or in combination in effective amounts without any loss of thermo-responsiveness in the hydrogel. Therapeutic use of the thermo-responsive hydrogel in the intratumoural treatment of solid cancer is also described.
    Type: Grant
    Filed: November 7, 2018
    Date of Patent: December 27, 2022
    Assignee: THE ROYAL COLLEGE OF SURGEONS IN IRELAND
    Inventors: Helena Kelly, Garry Duffy, Seona Rossi, Conn Hastings
  • A THERMO-RESPONSIVE HYDROGEL FOR INTRATUMORAL ADMINISTRATION AS A TREATMENT IN SOLID TUMOR CANCERS
    Publication number: 20200360281
    Abstract: A room temperature injectable thermo-responsive hydrogel comprises a P407 poloxamer base hydrogel, chitosan, 2-Hydroxypropyl ?-cyclodextrin and genipin. The chitosan and genipin form an interpenetrating scaffold within the hydrogel in which the chitosan is crosslinked with genipin. Chemotherapeutic drugs can be added to the hydrogel singly or in combination in effective amounts without any loss of thermo-responsiveness in the hydrogel. Therapeutic use of the thermo-responsive hydrogel in the intratumoural treatment of solid cancer is also described.
    Type: Application
    Filed: November 7, 2018
    Publication date: November 19, 2020
    Inventors: Helena Kelly, Garry Duffy, Seona Rossi, Conn Hastings