Patents by Inventor Helena Ostolaza Etxabe

Helena Ostolaza Etxabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR THE INTERNALIZATION OF NON-INVASIVE BACTERIA IN EUKARYOTE CELLS
    Publication number: 20100285068
    Abstract: The present invention relates to the use of adenylate cyclase toxin (ACT), or a functionally equivalent variant thereof, as an inducing agent for the internalization of non-invasive bacteria in eukaryotic cells. Due to ACT, said non-invasive bacterium can move through the plasma membrane of a eukaryotic cell and transfer plasmid DNA to said cell, which is useful for releasing or introducing molecules of therapeutic interest, for example, antigens, in the interior of the eukaryotic cell, thereby triggering the immune response.
    Type: Application
    Filed: June 27, 2008
    Publication date: November 11, 2010
    Applicant: UNIVERSIDAD DEL PAIS VASCO
    Inventors: Helena Ostolaza Etxabe, César Martín Plágaro, Félix Maria Goñi Urcelay