Patents by Inventor Helene Gazzano-Santoro

Helene Gazzano-Santoro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipopolysaccharide binding protein derivatives
    Publication number: 20030180303
    Abstract: Disclosed are novel biologically active lipopolysaccharide binding protein (LBP) derivatives including LBP derivative hybrid proteins which are characterized by the ability to bind to and neutralize LPS and which lack the CD14-mediated immunostimutlatory properties of holo-LBP.
    Type: Application
    Filed: April 23, 2002
    Publication date: September 25, 2003
    Applicant: XOMA Technology Ltd.
    Inventors: Helene Gazzano-Santoro, Georgia Theofan, Patrick Trown
  • Lipopolysaccharide binding protein derivatives
    Patent number: 5731415
    Abstract: Disclosed are novel biologically active lipopolysaccharide binding protein (LBP) derivatives including LBP derivative hybrid proteins which are characterized by the ability to bind to and neutralize LPS and which lack the CD14-mediated immunostimulatory properties of holo-LBP.
    Type: Grant
    Filed: June 17, 1994
    Date of Patent: March 24, 1998
    Assignee: XOMA Corporation
    Inventors: Helene Gazzano-Santoro, Georgia Theofan, Patrick W. Trown
  • Therapeutic uses of bactericidal/permeability increasing protein products
    Patent number: 5348942
    Abstract: The present invention provides therapeutic methods for treatment of conditions including the neutralization of the anti-coagulant activity of heparin, inhibition of angiogenesis, tumor and endothelial cell proliferation, and treatment of chronic inflammatory diseases by administration of bactericidal/permeability-increasing (BPI) protein products.
    Type: Grant
    Filed: March 12, 1993
    Date of Patent: September 20, 1994
    Assignee: Xoma Corporation
    Inventors: Roger G. Little, II, Helene Gazzano-Santoro, James B. Parent