Patents by Inventor Helmut Klocker

Helmut Klocker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150197820
    Abstract: The present invention relates to novel marker sequences for inflammatory prostate diseases, prostate carcinoma and the diagnostic use thereof together with a method for screening of potential active substances for inflammatory prostate diseases, prostate carcinoma by means of these marker sequences. Furthermore, the invention relates to a diagnostic device containing such marker sequences for inflammatory prostate diseases, prostate carcinoma, in particular a protein biochip and the use thereof.
    Type: Application
    Filed: March 30, 2015
    Publication date: July 16, 2015
    Inventors: Helmut E. MEYER, Angelika Lueking, Jens Beator, Axel Kowald, Georg Bartsch, Helmut Klocker
  • Publication number: 20140371095
    Abstract: The present invention relates to a novel method for identifying specific marker sequences for diagnosis of prostate cancer and/or for prognosis in prostate cancer, and to the use of the specific marker sequences identified with the aid of this method.
    Type: Application
    Filed: November 14, 2012
    Publication date: December 18, 2014
    Applicant: Protagen AG
    Inventors: Peter Amersdorfer, Angelika Lueking, Axel Kowald, Bettina Schlick, Petra Massoner, Christof Seifart, Georg Schäfer, Helmut Klocker, Peter Schulz-Knappe, Klaus Marquart
  • Publication number: 20140179557
    Abstract: The present invention relates to novel marker sequences for prostate carcinoma while excluding inflammatory prostate diseases or diabetes or polymorbidity and relates to their diagnostic use including a method for screening potential active substances for such prostate diseases by means of these marker sequences. The invention furthermore relates to a diagnostic device including such marker sequences for prostate carcinoma, in particular a protein biochip and its use.
    Type: Application
    Filed: February 24, 2014
    Publication date: June 26, 2014
    Applicant: PROTAGEN AKTIENGESELLSCHAFT
    Inventors: ANGELIKA LUEKING, AXEL KOWALD, HELMUT KLOCKER
  • Publication number: 20130217591
    Abstract: The present invention relates to novel marker sequences for inflammatory prostate diseases, prostate carcinoma and the diagnostic use thereof together with a method for screening of potential active substances for inflammatory prostate diseases, prostate carcinoma by means of these marker sequences. Furthermore, the invention relates to a diagnostic device containing such marker sequences for inflammatory prostate diseases, prostate carcinoma, in particular a protein biochip and the use thereof.
    Type: Application
    Filed: April 10, 2013
    Publication date: August 22, 2013
    Applicant: PROTAGEN AKTIENGESELLSCHAFT
    Inventors: HELMUT E. MEYER, ANGELIKA LUEKING, JENS BEATOR, AXEL KOWALD, GEORG BARTSCH, HELMUT KLOCKER
  • Publication number: 20120326025
    Abstract: The invention discloses the use of at least one substance selected from the group consisting of Phosphatidylcholine with diacyl residue sum C24:0 (PC aa C24:0); Phosphatidylcholine with diacyl residue sum C40:3 (PC ae C40:3); Phosphatidylcholine with diacyl residue sum C40:4 (PC ae C40:4); Lysophosphatidylcholine with acyl residue sum C26:0 (lysoPC a C26:0); Lysophosphatidylcholine with acyl residue sum C6:0 (lysoPC a C6:0); 13(S)-hydroxy-9Z,11E-octadecadienoic acid (13S-HODE); 12(S)-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid (12S-HETE); 15(S)-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid (15S-HETE); Leukotriene B4 (LTB4); Prostaglandin E2 (PGE2); Prostaglandin D2 (PGD2); 7?-Hydroxycholesterol (7aOHC); 7-Ketocholesterol (7KC); 5?,6?-Epoxycholesterol (5b,6b,EPC); 5g302,6g302-Epoxycholesterol (5a,6a,EPC); and 4?-Hydroxycholesterol (4BOHC); for prognosticating relapse of a prostate cancer (PCa) in a sample of a body fluid or a tissue sample of a PCa patient.
    Type: Application
    Filed: January 28, 2011
    Publication date: December 27, 2012
    Applicant: IMG Institut fur Medizinische Genomforschung Planu ngsgesellschaft
    Inventors: Klaus Weinberger, Hans-Peter Deigner, Emeka Ignatius Igwe, David Enot, Guido Dallmann, Helmut Klocker
  • Publication number: 20110275528
    Abstract: The present invention relates to novel marker sequences for inflammatory prostate diseases, prostate carcinoma and the diagnostic use thereof together with a method for screening of potential active substances for inflammatory prostate diseases, prostate carcinoma by means of these marker sequences. Furthermore, the invention relates to a diagnostic device containing such marker sequences for inflammatory prostate diseases, prostate carcinoma, in particular a protein biochip and the use thereof.
    Type: Application
    Filed: July 6, 2009
    Publication date: November 10, 2011
    Applicant: PROTAGEN Aktiengesellschaft
    Inventors: Helmut E. Meyer, Angelika Leukling, Jens Beator, Axel Kowald, Georg Bartsch, Helmut Klocker
  • Publication number: 20110165178
    Abstract: The present invention relates to vitro diagnosis methods of prostate cancer from a test biological sample, comprising measuring the expression level of KIAA0153 in said test biological sample, as well as to methods for screening compounds inhibiting KIAA0153 gene expression or biological activity and uses of such KIAA0153 inhibiting compounds.
    Type: Application
    Filed: January 23, 2008
    Publication date: July 7, 2011
    Inventors: Bohdan Wasylyk, Alberto Zambrano, Joseph Abecassis, Helmut Klocker, Jack A. Schalken
  • Patent number: 7759068
    Abstract: The present invention relates to the use of an active ingredient and to a method for the prevention or treatment of tumors, the diagnostic detection of disorders associated with these tumors, and pharmaceutical compositions and kits related thereto.
    Type: Grant
    Filed: April 15, 2003
    Date of Patent: July 20, 2010
    Assignee: Proteosys AG
    Inventors: Michael Cahill, Wojciech Wozny, André Schrattenholz, Helmut Klocker, Hermann Rogatsch
  • Publication number: 20070172900
    Abstract: The invention relates to the use of various proteins as diagnostic markers for cancerous diseases. In particular, the use of the annexin A3 protein is preferred. Preferably an increased regulation of annexin A3 is analysed in comparison to controls. The invention also relates to the use of active substances for producing a medicament used in the treatment of cancer, said substances influencing the activity and/or abundance of various characteristic proteins.
    Type: Application
    Filed: February 16, 2005
    Publication date: July 26, 2007
    Applicant: PROTEOSYS AG
    Inventors: Michael Cahill, Helmut Klocker, Herman Rogatsch
  • Publication number: 20050130876
    Abstract: The present invention relates to the use of an active ingredient and to a method for the prevention or treatment of tumors, the diagnostic detection of disorders associated with these tumors, and pharmaceutical compositions and kits related thereto.
    Type: Application
    Filed: April 15, 2003
    Publication date: June 16, 2005
    Inventors: Michael Cahill, Wojciech Wozny, Andre Schrattenholz, Helmut Klocker, Hermann Rogatsch