Patents by Inventor Hemanta Kole

Hemanta Kole has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the isolation of a nontoxinogenic vibrio cholerae strain and a process for preparing cholera vaccine from said vibrio cholerae strain
    Patent number: 6106843
    Abstract: A process for the isolation of nontoxinogenic V. cholerae strain and a process for preparing a cholera vaccine from said V. cholerae strain, said process comprising (a) isolating V. cholerae from the stool of a patient suffering from cholera by spreading the stool on a selector medium specific for V. cholerae, (b) separating the non-toxinogenic V. cholerae strain from the population of the V. cholerae strains isolated in step (a), and (c) incorporating immunogenic cholera toxin (ctx) B subunit gene into the chromosome of the strain by conventional methods to produce the vaccine.
    Type: Grant
    Filed: February 3, 1999
    Date of Patent: August 22, 2000
    Assignees: Council of Scientific & Industrial Research, National Institute of Cholera and Enteric Diseases, Department of Biotechnology
    Inventors: Thungapathra Muthukumarappa, Amit Ghosh, Charu Sharma, Naveen Gupta, Asish Mukhopadhyay, Hemanta Kole, Gopinath Balakrish Nair, Ranajit Kumar Ghosh