Patents by Inventor Hendrik Jan Cornelis Meijerink
Hendrik Jan Cornelis Meijerink has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230241078Abstract: The current invention relates to the use of a physiologically acceptable organic and/or inorganic vanadium compound or complex, such as for example bis(maltolato)oxovanadium (BMOV) in the prevention or amelioration of stress-induced metabolic derangement in a subject. More in particular, the invention relates to a physiologically acceptable organic and/or inorganic vanadium compound or complex for use in the amelioration of hyperglycemia in a subject suffering from stress such as elicited by a trauma, wherein the physiologically acceptable organic and/or inorganic vanadium compound or complex is administered to said subject before the trauma is inflicted to the subject.Type: ApplicationFiled: January 13, 2023Publication date: August 3, 2023Applicant: CFM Pharma Holding B.V.Inventors: Hendrik Jan Cornelis Meijerink, Josephus Johannes De Kimpe, Lekhram Changoer
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Publication number: 20230115025Abstract: The invention relates to floating drug delivery systems (FDDS) that provide solutions to the particular problems often encountered with floating drug delivery systems described in the art. On such generally recognized problem is the vulnerability of the systems, especially damage to the gas-filled compartment making it accessible to water so as to impair its buoyancy, ultimately resulting in insufficient gastric residence time. The invention, in an aspect, provides a self-repairing FDDS that maintains its floating capacity after damaging. The floating drug delivery systems of the invention, furthermore, allow for incorporation of high loads of active ingredients. The floating drug delivery systems can be designed in such a way that release of active ingredient from the system occurs entirely independent from the pH of the fluid surrounding the system.Type: ApplicationFiled: June 7, 2022Publication date: April 13, 2023Applicant: APeT Holding B.V.Inventors: Hendrik Jan Cornelis Meijerink, Lekhram Changoer, Willem Blom, Marinella Regina Visser, Henderik Willem Frijlink, Anko Cornelus Eissens
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Publication number: 20220040195Abstract: The present invention relates to a method for maintaining normoglycemia in a mammal in need thereof, preferably a critically ill patient suffering from acute stress, and to a method for preventing or limiting renal ischemia-reperfusion (I/R) in a mammal, preferably in a critically ill patient suffering from acute stress.Type: ApplicationFiled: October 22, 2021Publication date: February 10, 2022Applicant: CFM Pharma Holding BVInventors: Hendrik Jan Cornelis Meijerink, Lekhram Changoer
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Patent number: 11179401Abstract: The present invention relates to a method for maintaining normoglycemia in a mammal in need thereof, preferably a critically ill patient suffering from acute stress, and to a method for preventing or limiting renal ischemia-reperfusion (I/R) in a mammal, preferably in a critically ill patient suffering from acute stress.Type: GrantFiled: September 16, 2019Date of Patent: November 23, 2021Assignee: CFM PHARMA HOLDING BVInventors: Hendrik Jan Cornelis Meijerink, Lekhram Changoer
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Patent number: 10881614Abstract: The present invention relates to compositions and methods for the prophylaxis or treatment of deficiencies in essential amino acid absorption and metabolism and/or of a pathology or symptom associated there with. In particular the invention concerns the treatment and/or prevention of ADHD, ADD and autism spectrum disorders. The present inventors have developed a method for prophylaxis or treatment of such symptoms and/or pathologies associated with a deficiency in essential amino acid absorption and/or metabolism, which method, stated generally, relies on the administration of nicotinamide, typically in a long-acting formulation so as to overcome the deficiencies of existing formulations, which have proven unsuitable for effective treatment.Type: GrantFiled: September 28, 2017Date of Patent: January 5, 2021Assignee: APeT Holding B.V.Inventors: Hendrik Jan Cornelis Meijerink, Lekhram Changoer, Willem Blom, Marinella Regina Visser, Henderik Willem Frijlink, Anko Cornelus Eissens
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Publication number: 20200246352Abstract: The current invention relates to the use of a physiologically acceptable organic and/or inorganic vanadium compound or complex, such as for example bis(maltolato)oxovanadium (BMOV) in the prevention or amelioration of stress-induced metabolic derangement in a subject. More in particular, the invention relates to a physiologically acceptable organic and/or inorganic vanadium compound or complex for use in the amelioration of hyperglycemia in a subject suffering from stress such as elicited by a trauma, wherein the physiologically acceptable organic and/or inorganic vanadium compound or complex is administered to said subject before the trauma is inflicted to the subject.Type: ApplicationFiled: September 21, 2018Publication date: August 6, 2020Applicant: CFM Pharma Holding B.V.Inventors: Hendrik Jan Cornelis Meijerink, Josephus Johannes de Kimpe, Lekhram Changoer
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Publication number: 20200078372Abstract: The present invention relates to a method for maintaining normoglycemia in a mammal in need thereof, preferably a critically ill patient suffering from acute stress, and to a method for preventing or limiting renal ischemia-reperfusion (I/R) in a mammal, preferably in a critically ill patient suffering from acute stress.Type: ApplicationFiled: September 16, 2019Publication date: March 12, 2020Inventors: Hendrik Jan Cornelis MEIJERINK, Lekhram CHANGOER
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Publication number: 20180140553Abstract: The present invention relates to compositions and methods for the prophylaxis or treatment of deficiencies in essential amino acid absorption and metabolism and/or of a pathology or symptom associated there with. In particular the invention concerns the treatment and/or prevention of ADHD, ADD and autism spectrum disorders. The present inventors have developed a method for prophylaxis or treatment of such symptoms and/or pathologies associated with a deficiency in essential amino acid absorption and/or metabolism, which method, stated generally, relies on the administration of nicotinamide, typically in a long-acting formulation so as to overcome the deficiencies of existing formulations, which have proven unsuitable for effective treatment.Type: ApplicationFiled: September 28, 2017Publication date: May 24, 2018Applicant: APeT Holding B.V.Inventors: Hendrik Jan Cornelis Meijerink, Lekhram Changoer, Willem Blom, Marinella Regina Visser, Henderik Willem Frijlink, Anko Cornelus Eissens
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Publication number: 20180078503Abstract: The invention relates to floating drug delivery systems (FDDS) that provide solutions to the particular problems often encountered with floating drug delivery systems described in the art. On such generally recognized problem is the vulnerability of the systems, especially damage to the gas-filled compartment making it accessible to water so as to impair its buoyancy, ultimately resulting in insufficient gastric residence time. The invention, in an aspect, provides a self-repairing FDDS that maintains its floating capacity after damaging. The floating drug delivery systems of the invention, furthermore, allow for incorporation of high loads of active ingredients. The floating drug delivery systems can be designed in such a way that release of active ingredient from the system occurs entirely independent from the pH of the fluid surrounding the system.Type: ApplicationFiled: September 28, 2017Publication date: March 22, 2018Applicant: APeT Holding B.V.Inventors: Hendrik Jan Cornelis Meijerink, Lekhram Changoer, Willem Blom, Marinella Regina Visser, Henderik Willem Frijlink, Anko Cornelus Eissens
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Publication number: 20150202158Abstract: The invention relates to floating drug delivery systems(FDDS) that provide solutions to the particular problems often encountered with floating drug delivery systems described in the art. On such generally recognized problem is the vulnerability of the systems, especially damage to the gas-filled compartment making it accessible to water so as to impair its buoyancy, ultimately resulting in insufficient gastric residence time. The invention, in an aspect, provides a self-repairing FDDS that maintains its floating capacity after damaging. The floating drug delivery systems of the invention, furthermore,allow for incorporation of high loads of active ingredients. The floating drug delivery systems can be designed in such a way that release of active ingredient from the system occurs entirely independent from the pH of the fluid surrounding the system.Type: ApplicationFiled: July 15, 2013Publication date: July 23, 2015Applicant: APeT Holding B.V.Inventors: Hendrik Jan Cornelis Meijerink, Lekhram Changoer, Willem Blom, Marinella Regina Visser, Henderik Willem Frijlink, Anko Cornelus Eissens
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Publication number: 20140234409Abstract: The present invention relates to compositions and methods for the prophylaxis or treatment of deficiencies in essential amino acid absorption and metabolism and/or of a pathology or symptom associated there with. In particular the invention concerns the treatment and/or prevention of ADHD, ADD and autism spectrum disorders. The present inventors have developed a method for prophylaxis or treatment of such symptoms and/or pathologies associated with a deficiency in essential amino acid absorption and/or metabolism, which method, stated generally, relies on the administration of nicotinamide, typically in a long-acting formulation so as to overcome the deficiencies of existing formulations, which have proven unsuitable for effective treatment.Type: ApplicationFiled: July 16, 2012Publication date: August 21, 2014Inventors: Hendrik Jan Cornelis Meijerink, Lekhram Changoer, Willem Blom, Marinella Regina Visser, Henderik Willem Frijlink, Anko Cornelus Eissens
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Publication number: 20140072647Abstract: The present invention relates to a method for maintaining normoglycemia in a mammal in need thereof, preferably a critically ill patient suffering from acute stress, and to a method for preventing or limiting renal ischemia-reperfusion (I/R) in a mammal, preferably in a critically ill patient suffering from acute stress.Type: ApplicationFiled: March 6, 2012Publication date: March 13, 2014Inventors: Hendrik Jan Cornelis Meijerink, Lekhram Changoer
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Publication number: 20080274206Abstract: The present invention relates to stabilised liquid oxygen releasing composition comprising a component (a) selected from the salts consisting of cations An+ and anions derived from halogen oxides according to the general formula [OmX]? wherein A is a metal selected from Groups 1 or 2 of the Periodic System of the Elements, X is a halogen atom, m=1-4, n=1 or 2, a component (b) selected from the group of oxygen donors, a component (c) selected from the group of oxygen donor stabilising agents and a component (d) selected from the group of liquid binders. The stabilised liquid oxygen releasing composition can be used in pharmaceutical compositions, cosmetic compositions and food applications, e.g. skin care products, dental care products, tooth whitening products including chewing gums.Type: ApplicationFiled: July 10, 2005Publication date: November 6, 2008Inventors: Changoer Lekhram, Willem Frederik Van Den Bosch, Hendrik Jan Cornelis Meijerink
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Publication number: 20080220088Abstract: The invention discloses the use of a liquid composition, capable of promoting the growth of tissue cells at the site of a wound, a process that promotes regeneration of tissue and wound healing. More particularly, the present invention relates to the use of a liquid composition comprising a component (a) selected from the salts consisting of cations An+ and anions derived from halogen oxides according to the general formula [OmX]?, a component (b) selected from the group of oxygen donors, and a component (d) selected from the group of liquid binders for the treatment of open wounds and burns.Type: ApplicationFiled: October 7, 2005Publication date: September 11, 2008Applicant: NGEN PHARMACEUTICALS N.V.Inventors: Changoer Lekhram, Willem Frederik Van Den Bosch, Hendrik Jan Cornelis Meijerink