Patents by Inventor Hendrik M. Van Rossum

Hendrik M. Van Rossum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Applications of CRISPRi in high throughput metabolic engineering
    Patent number: 11130955
    Abstract: Methods, compositions, and kits for high throughput DNA assembly reactions in vitro. Modular CRISPR DNA constructs comprising modular insert DNA parts flanked by cloning tag segments comprising pre-validated CRISPR protospacer/protospacer adjacent motif sequence combinations. High throughput methods of CRISPRi and CRISPRa.
    Type: Grant
    Filed: August 15, 2019
    Date of Patent: September 28, 2021
    Assignee: Zymergen Inc.
    Inventors: Brian Chaikind, Hendrik M. Van Rossum, Aaron Miller, Paul Perkovich, Shawn Szyjka, Kedar Patel
  • APPLICATIONS OF CRISPRi IN HIGH THROUGHPUT METABOLIC ENGINEERING
    Publication number: 20200056191
    Abstract: The disclosure describes methods, compositions, and kits for high throughput DNA assembly reactions in vitro. The disclosure further describes modular CRISPR DNA constructs comprising modular insert DNA parts flanked by cloning tag segments comprising pre-validated CRISPR protospacer/protospacer adjacent motif sequence combinations. High throughput methods of CRISPRi and CRISPRa are also disclosed.
    Type: Application
    Filed: August 15, 2019
    Publication date: February 20, 2020
    Inventors: Brian Chaikind, Hendrik M. Van Rossum, Aaron Miller, Paul Perkovich, Shawn Szyjka, Kedar Patel