Patents by Inventor Henk Pieters

Henk Pieters has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating breast cancer using antibody binding to MMP-14
    Patent number: 9051377
    Abstract: Proteins that bind to matrix metalloproteinase 14 and methods of using such proteins are described.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: June 9, 2015
    Assignee: Dyax Corp.
    Inventors: Laetitia Devy, Henk Pieters, Robert C. Ladner, Rene Hoet, Daniel T. Dransfield, Clive R. Wood, Maria Henderikx
  • METALLOPROTEINASE BINDING PROTEINS
    Publication number: 20120107231
    Abstract: Proteins that bind to matrix metalloproteinase 14 and methods of using such proteins are described.
    Type: Application
    Filed: December 22, 2011
    Publication date: May 3, 2012
    Applicant: DYAX CORP.
    Inventors: Laetitia Devy, Henk Pieters, Robert C. Ladner, Rene Hoet, Daniel T. Dransfield, Clive R. Wood, Maria Henderikx
  • Metalloproteinase binding proteins
    Patent number: 8106168
    Abstract: Proteins that bind to matrix metalloproteinase 14 and methods of using such proteins are described.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: January 31, 2012
    Assignee: Dyax Corp.
    Inventors: Laetitia Devy, Henk Pieters, Robert C. Ladner, Rene Hoet, Daniel T. Dransfield, Clive R. Wood, Maria Henderikx
  • TIE COMPLEX BINDING PROTEINS
    Publication number: 20110059105
    Abstract: Tie1 and Tie2 are receptor tyrosine kinase proteins that include a transmembrane domain. Tie1 and Tie2 are present on endothelial cells. This disclosure describes agents, such as antibodies, that bind to Tie1, Tie2, and Ang, including ones that inhibit endothelial cell activity.
    Type: Application
    Filed: June 28, 2010
    Publication date: March 10, 2011
    Applicant: DYAX CORP.
    Inventors: Clive R. Wood, Daniel T. Dransfield, Henk Pieters, Rene Hoet, Simon E. Hufton
  • Antibodies to Tie1 ectodomain
    Patent number: 7871610
    Abstract: Tie1 and Tie2 are receptor tyrosine kinase proteins that include a transmembrane domain. Tie1 and Tie2 are present on endothelial cells. This disclosure describes agents, such as antibodies, that bind to Tie1, Tie2, and Ang, including ones that inhibit endothelial cell activity.
    Type: Grant
    Filed: February 2, 2005
    Date of Patent: January 18, 2011
    Assignee: Dyax Corp.
    Inventors: Clive R. Wood, Daniel T. Dransfield, Henk Pieters, Rene Hoet, Simon E. Hufton
  • Metalloproteinase Binding Proteins
    Publication number: 20100266490
    Abstract: Proteins that bind to matrix metalloproteinase 14 and methods of using such proteins are described.
    Type: Application
    Filed: May 7, 2010
    Publication date: October 21, 2010
    Applicant: DYAX CORP.
    Inventors: Laetitia Devy, Henk Pieters, Robert C. Ladner, Rene Hoet, Daniel T. Dransfield, Clive R. Wood, Maria Henderikx
  • Method of inhibition of vascular development using an antibody
    Publication number: 20100196361
    Abstract: Tie1 and Tie2 are receptor tyrosine kinase proteins that include a transmembrane domain. Tie1 and Tie2 are present on endothelial cells. This disclosure describes agents, such as antibodies, that bind to Tie1, Tie2, and Ang, including ones that inhibit endothelial cell activity and angiogenesis. The agents can be used to treat angiogenesis-associated disorders.
    Type: Application
    Filed: December 17, 2008
    Publication date: August 5, 2010
    Applicant: DYAX CORP.
    Inventors: Clive R. Wood, Daniel T. Dransfield, Henk Pieters, Rene Hoet, Simon E. Hufton
  • Antibodies that bind MMP-14
    Patent number: 7745587
    Abstract: Proteins that bind to matrix metalloproteinase 14 and methods of using such proteins are described.
    Type: Grant
    Filed: December 29, 2006
    Date of Patent: June 29, 2010
    Assignee: Dyax Corp.
    Inventors: Laetitia Devy, Henk Pieters, Robert C. Ladner, Rene Hoet, Daniel T. Dransfield, Clive R. Wood, Maria Henderikx
  • Method of inhibition of vascular development using an antibody
    Patent number: 7485297
    Abstract: Tie1 and Tie2 are receptor tyrosine kinase proteins that include a transmembrane domain. Tie1 and Tie2 are present on endothelial cells. This disclosure describes agents, such as antibodies, that bind to Tie1, Tie2, and Ang, including ones that inhibit endothelial cell activity and angiogenesis. The agents can be used to treat angiogenesis-associated disorders.
    Type: Grant
    Filed: August 9, 2005
    Date of Patent: February 3, 2009
    Assignee: Dyax Corp.
    Inventors: Clive R. Wood, Daniel T. Dransfield, Henk Pieters, Rene Hoet, Simon E. Hufton
  • TIE1-BINDING LIGANDS
    Publication number: 20080254021
    Abstract: Tie1 is a receptor tyrosine kinase protein that includes a transmembrane domain. Tie1 is present on endothelial cells. This disclosure described antibodies that bind to Tie1, including ones that inhibit endothelial cell activity.
    Type: Application
    Filed: January 25, 2008
    Publication date: October 16, 2008
    Applicant: DYAX CORP.
    Inventors: Simon E. Hufton, Rene Hoet, Henk Pieters
  • Tie1-binding ligands
    Patent number: 7348001
    Abstract: Tie1 is a receptor tyrosine kinase protein that includes a transmembrane domain. Tie1 is present on endothelial cells. This disclosure described antibodies that bind to Tie1, including ones that inhibit endothelial cell activity.
    Type: Grant
    Filed: August 12, 2004
    Date of Patent: March 25, 2008
    Assignee: Dyax Corp.
    Inventors: Simon E. Hufton, Rene Hoet, Henk Pieters
  • Metalloproteinase binding proteins
    Publication number: 20070217997
    Abstract: Proteins that bind to matrix metalloproteinase 14 and methods of using such proteins are described.
    Type: Application
    Filed: December 29, 2006
    Publication date: September 20, 2007
    Inventors: Laetitia Devy, Henk Pieters, Robert Ladner, Rene Hoet, Daniel Dransfield, Clive Wood
  • Tie complex binding proteins
    Publication number: 20060057138
    Abstract: Tie1 and Tie2 are receptor tyrosine kinase proteins that include a transmembrane domain. Tie1 and Tie2 are present on endothelial cells. This disclosure describes agents, such as antibodies, that bind to Tie1, Tie2, and Ang, including ones that inhibit endothelial cell activity and angiogenesis. The agents can be used to treat angiogenesis-associated disorders.
    Type: Application
    Filed: August 9, 2005
    Publication date: March 16, 2006
    Inventors: Clive Wood, Daniel Dransfield, Henk Pieters, Rene Hoet, Simon Hufton
  • Tie complex binding proteins
    Publication number: 20060024297
    Abstract: Tie1 and Tie2 are receptor tyrosine kinase proteins that include a transmembrane domain. Tie1 and Tie2 are present on endothelial cells. This disclosure describes agents, such as antibodies, that bind to Tie1, Tie2, and Ang, including ones that inhibit endothelial cell activity.
    Type: Application
    Filed: February 2, 2005
    Publication date: February 2, 2006
    Inventors: Clive Wood, Daniel Dransfield, Henk Pieters, Rene Hoet, Simon Hufton
  • Tie1-binding ligands
    Publication number: 20050136053
    Abstract: Tie1 is a receptor tyrosine kinase protein that includes a transmembrane domain. Tie1 is present on endothelial cells. This disclosure described antibodies that bind to Tie1, including ones that inhibit endothelial cell activity.
    Type: Application
    Filed: August 12, 2004
    Publication date: June 23, 2005
    Inventors: Simon Hufton, Rene Hoet, Henk Pieters
  • Method and apparatus for washing magnetically responsive particles
    Publication number: 20030170686
    Abstract: The invention features apparati and methods for washing magnetically responsive particles such as paramagnetic beads. One exemplary apparatus includes a flow chamber having an inlet and an outlet; and at least a first magnetic field inducer. The apparatus is configured such that a first magnetic field can be selectively applied in the flow chamber. The apparatus can also apply a flow of fluid to the chamber in coordination with the selective application of the magnetic field.
    Type: Application
    Filed: December 6, 2002
    Publication date: September 11, 2003
    Inventors: Rene Hoet, Henricus Renerus Jacobus Mattheus Hoogenboom, Henk Pieters, Robert C. Ladner, Shannon Hogan, Kristin Rookey