Abstract: An oral composition of Benzazepin-1-acetic acid derivatives is provided comprising: a) an active compound in an amount of between 10 and 65% of the total weight of the formulation; b) at least 10% w/w an alkaline compound or a mixture of alkaline compounds; c) optionally comprising auxiliary materials an amount of between 1% and 45% of the total weight of the formulation The invention also provides an oral composition comprising sodium carbonate with a specific particle size and/or surface area as alkaline compound.

Abstract: An immediate release pharmaceutical formulation of a poorly water-soluble biologically active substance with enhanced bio-availability, the formulation being a homogeneous and thermostable solid solution, and the solid solution including as percentages of the total weight of the formulation: a) 10 to 50% of the active substance; b) 20 to 70% of a non-ionic hydrophilic surfactant which is liquid between 15 and 30° C.; c) 5 to 70% of a pharmaceutically acceptable organic polymer or polymer mixture which is liquid above 60° C. and solid below 30° C., and d) optionally, 1 to 10% of a disintegrating agent; as well as active substances formulated into such form, and methods for producing such formulations.