Abstract: Array including a first and a second monolith of a structured catalyst for carrying out an endothermic reaction of a feed gas, wherein: a) the first and second monolith include a macroscopic structure of a first and second electrically conductive material; b) each of said first and second monoliths has a number of flow channels formed therein for conveying feed gas through the monoliths; c) the array includes at least a first and a second conductor electrically connected to said first and second monoliths, respectively, and to an electrical power supply, d) the first and second monolith are electrically connected by a monolith bridge; e) the array is configured to direct an electrical current to run from the first conductor through the first monolith to a second end, then through the bridge, and then through the second monolith to the second conductor.

Abstract: The invention relates to a method of manufacturing a composite component (21) having a varying electric resistivity along a longitudinal direction of the component. At least a first paste (10a) having a first composition, and at least a second paste (10b) having a second composition are prepared. The pastes are transferred into a supply chamber (35) of a processing equipment (31), such as an extruder. A green body (20) is shaped by forcing the pastes from the supply chamber through a die (32), and the green body is then sintered or oxidized to form the composite component. The pastes may comprise metal powder, ceramic powder, and binder. The varying electric resistivity may be due to variations in one or more of the following parameters: the volume ratio between the metal powder and the ceramic powder, the size of the ceramic particles, and the type of the ceramic material.

Abstract: The invention relates to a method of manufacturing an object (24) by joining a first component (25) and a second component (26). The first component comprises metal powder with a first alloy composition and a first soluble binder, and the second component comprises metal powder with a second alloy composition and a second soluble binder. They may further comprise ceramic powder. At least one of the surfaces to be joined is dissolved before they are brought in contact, or a mixture of metal powder with a third alloy composition and a dissolved third binder is arranged there between. The chemical differences between the first, second, and third alloy compositions are within predetermined limits. The components are sintered or oxidized together whereby it is possible to obtain an object wherein the transitions between the material phases from the joined components are close to inconspicuous when analysed with scanning electron microscopy.

Abstract: The invention relates to a heating system (200) for heating of a fluid. The heating system comprises a supply connection (201) in fluid communication with a supply of fluid to be heated. It further comprises a structured body (108) arranged for heating of the fluid during use of the heating system. The structured body comprises a macroscopic structure (21) of electrically conductive material, the macroscopic structure comprising at least one channel (22) through which the fluid can flow. The heating system further comprises at least two conductors (103,114) configured to electrically connect the structured body to at least one electrical power supply. The at least two conductors are electrically connected to the structured body at a first end (204) and at a second end (205), respectively, of a conductive path within the structured body. The structured body is configured to direct an electrical current to run along the conductive path from the first end to the second end thereof.

Abstract: The invention relates to a method of manufacturing a component (21) from metal-containing powder. A paste is prepared by mixing at least a powder (11) comprising metal, a binder (12) in an amount of 2 to 8 weight % of the paste (10), and liquid (13), such as water, in an amount of 5 to 25 weight % of the paste (10). The paste is transferred to an extruder (31), and the paste is extruded into a green body (20) by using an extrusion pressure (P) of more than 50 bar. Then the green body (20) is dried and sintered or oxidized to obtain the final component.

Abstract: The present disclosure provides methods for the treatment of irritable bowel syndrome (IBS) and/or functional dyspepsia. In particular, the present disclosure provides methods for the treatment of irritable bowel syndrome (IBS) and/or functional dyspepsia through administration of antibodies that bind to human Siglec-8 or compositions comprising said antibodies. The present disclosure also provides articles of manufacture or kits comprising antibodies that bind to human Siglec-8 for the treatment of irritable bowel syndrome (IBS) and/or functional dyspepsia.

Abstract: A magnetizer including a housing, a passage arranged inside the housing, and a permanent magnet assembly arranged outside the passage to provide a magnetic field passing through the passage. The housing defines an inlet to the passage and an outlet from the passage such that an object to be magnetised can be inserted into the passage via the inlet in the housing and removed via the outlet in the housing. The passage includes a uniform portion where opposing surfaces of the permanent magnet assembly are arranged a uniform distance apart along the length of the uniform portion and a diverging portion arranged between one end of the uniform portion of the passage and the outlet of the housing.

Abstract: The present disclosure provides methods and kits suitable for administering a composition comprising an antibody that binds to human Siglec-8, e.g., to a human individual in need thereof. In some embodiments, a corticosteroid is administered to the individual at least 6 hours, at least 12 hours, or 12-24 hours prior to the first dose of the composition comprising the anti-Siglec-8 antibody.

Abstract: The present disclosure provides methods for the treatment of mast cell gastritis, mast cell esophagitis, mast cell colitis, mast cell enteritis, mast cell duodenitis, and/or mast cell gastroenteritis. In particular, the present disclosure provides methods for the treatment of mast cell gastritis, mast cell esophagitis, mast cell colitis, mast cell enteritis, mast cell duodenitis, and/or mast cell gastroenteritis through administration of antibodies that bind to human Siglec-8 or compositions comprising said antibodies. The present disclosure also provides articles of manufacture or kits comprising antibodies that bind to human Siglec-8 for the treatment of mast cell gastritis, mast cell esophagitis, mast cell colitis, mast cell enteritis, mast cell duodenitis, and/or mast cell gastroenteritis.

Abstract: The present disclosure provides methods for the treatment of chronic urticaria. In particular, the present disclosure provides methods for the treatment of chronic urticaria through administration of antibodies that bind to human Siglec-8 or compositions comprising said antibodies. The present disclosure also provides articles of manufacture or kits comprising antibodies that bind to human Siglec-8 for the treatment of chronic urticaria.

Abstract: The present invention relates to a magnetic gear comprising a first magnetic rotor with a first shaft; and a second magnetic rotor with a second shaft; a support structure, with a first end shield and a second end shield connected by a stat or support element. A first bearing attached to the first end shield supports the first shaft and a second bearing supports the second shaft. The first and second magnetic rotors are displaced in axial direction from each other in an axial gap; and the first shaft and shaft are approximately aligned in opposite axial directions; and a plurality of magnetic flux conductors encircles the first and second magnetic rotors, thereby conducting magnetic flux from the first magnetic rotor to the second magnetic rotor. The magnetic gear comprises a dividing wall arranged in the axial gap between the first magnetic rotor and the magnetic second rotor, to separate a first chamber from a second chamber.

Abstract: A cartridge engageable with a medical device, the method of making a cartridge comprising an ordered arrangement of N electrical components each with different respective values of an electrical property, and an ordered arrangement of N conductors operably coupled to the ordered arrangement of the N electrical components. A medical device is arranged to receive a cartridge comprises for each of N conductors on the cartridge, at least a first respective contact arranged to electrically couple with the corresponding conductor when the cartridge is engaged with the medical device; the medical device also comprises an evaluation means operable to evaluate the different respective values of an electrical property of N electrical components on the cartridge, wherein the N electrical components form an ordered arrangement which is operably coupled to the N conductors on the cartridge, and a switching arrangement operable to selectively electrically couple a respective pair of contacts to said evaluation means.

Abstract: The present invention relates to a magnetic gear comprising a first magnetic rotor with a first shaft; and a second magnetic rotor with a second shaft; a support structure, with a first end shield and a second end shield connected by a stat or support element. A first bearing attached to the first end shield supports the first shaft and a second bearing supports the second shaft. The first and second magnetic rotors are displaced in axial direction from each other in an axial gap; and the first shaft and shaft are approximately aligned in opposite axial directions; and a plurality of magnetic flux conductors encircles the first and second magnetic rotors, thereby conducting magnetic flux from the first magnetic rotor to the second magnetic rotor. The magnetic gear comprises a dividing wall arranged in the axial gap between the first magnetic rotor and the magnetic second rotor, to separate a first chamber from a second chamber.

Abstract: The present invention relates to methods for the identification of a sentinel lymph node and to compounds and preparations used in said methods.

Abstract: A cartridge engageable with a medical device, the method of making a cartridge comprising an ordered arrangement of N electrical components each with different respective values of an electrical property, and an ordered arrangement of N conductors operably coupled to the ordered arrangement of the N electrical components. A medical device is arranged to receive a cartridge comprises for each of N conductors on the cartridge, at least a first respective contact arranged to electrically couple with the corresponding conductor when the cartridge is engaged with the medical device; the medical device also comprises an evaluation means operable to evaluate the different respective values of an electrical property of N electrical components on the cartridge, wherein the N electrical components form an ordered arrangement which is operably coupled to the N conductors on the cartridge, and a switching arrangement operable to selectively electrically couple a respective pair of contacts to said evaluation means.

Abstract: The present invention relates to methods for the identification of a sentinel lymph node and to compounds and preparations used in said methods.

Abstract: A cartridge is engageable with a medical device, the cartridge comprising an ordered arrangement of N electrical components (540) each with different respective values of an electrical property, and an ordered arrangement of N conductors (522, 524, 526) operably coupled to the ordered arrangement of the N electrical components.

Abstract: The invention relates to a triggered ultrasound imaging method for imaging of the myocardium, minimizing the risk of eliciting cardiac arrhythmia. Particularly, the invention is directed to a method of assessing cardiac perfusion. Destruction pulses are triggered such that they fall within the refractory period of the heart, while imaging pulses are triggered at any given time of the ECG cycle, preferably during end-systole.

Abstract: A computer-implemented method evaluates credit exposure of a portfolio of financial instruments. A deal object is established for each instrument. The deal object comprises a representation of the instrument and a valuation function for representing how the value of the instrument is related to underlying market variables. Risk factor model are established with each model representing a market variable which may affect the value of the instruments. A deal parabolic function is established representing each deal object valuation function by operation of the deal object valuation function on each risk factor model to which it is sensitive. The coefficients of each deal parabolic function established at a same instant from the deal objects represented in the portfolio are summed in order to build a portfolio parabolic function approximating the overall portfolio value for that instant.

Abstract: The invention provides a method for treating cancer in a human comprising administering to the human a dose of a pharmaceutical composition comprising (i) a pharmaceutically acceptable carrier and (ii) an adenoviral vector comprising a nucleic acid sequence encoding TNF-? operably linked to a promoter, wherein the dose comprises about 1×107 to about 4×1012 particle units (pu) of replication-deficient adenoviral vector, at least once in a therapeutic period comprising up to 10 weeks, whereby the cancer in human is treated. The invention further provides a method of treating a human for multiple tumors, wherein the method comprises contacting a first tumor with a dose of the pharmaceutical composition at least once in a therapeutic period comprising up to about 10 weeks, whereby the human is treated for the first tumor and one or more additional tumors.