Patents by Inventor Henry F. VanBrocklin

Henry F. VanBrocklin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PEPTIDOMIMETIC INHIBITORS OF PSMA
    Publication number: 20160215006
    Abstract: Compounds of the formulae, (I), wherein each variable is as defined herein are provided which are useful in (i) diagnostic methods for detecting and/or identifying cells presenting PSMA; (2) compositions comprising a compound of the invention together with a pharmaceutically acceptable carrier, excipient, and/or diluent; (3) methods for inhibiting or treating prostrate cancer; and (4) methods for blocking or destabilizing neovasculature of a tumor.
    Type: Application
    Filed: April 1, 2016
    Publication date: July 28, 2016
    Applicants: WASHINGTON STATE UNIVERSITY, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Clifford E. BERKMAN, Henry F. VANBROCKLIN
  • Peptidomimetic inhibitors of PSMA
    Patent number: 9328129
    Abstract: Compounds of the formulae, (I), wherein each variable is as defined herein are provided which are useful in (i) diagnostic methods for detecting and/or identifying cells presenting PSMA; (2) compositions comprising a compound of the invention together with a pharmaceutically acceptable carrier, excipient, and/or diluent; (3) methods for inhibiting or treating prostrate cancer; and (4) methods for blocking or destabilizing neovasculature of a tumor.
    Type: Grant
    Filed: November 10, 2011
    Date of Patent: May 3, 2016
    Assignees: Washington State University, The Regents of the University of California
    Inventors: Clifford E. Berkman, Henry F. Vanbrocklin
  • PEPTIDOMIMETIC INHIBITORS OF PSMA
    Publication number: 20140010758
    Abstract: Compounds of the formulae, (I), wherein each variable is as defined herein are provided which are useful in (i) diagnostic methods for detecting and/or identifying cells presenting PSMA; (2) compositions comprising a compound of the invention together with a pharmaceutically acceptable carrier, excipient, and/or diluent; (3) methods for inhibiting or treating prostrate cancer; and (4) methods for blocking or destabilizing neovasculature of a tumor.
    Type: Application
    Filed: November 10, 2011
    Publication date: January 9, 2014
    Applicants: THE REGEANTS OF THE UNIVERSITY OF CALIFORNIA, WASHINGTON STATE UNIVERSITY
    Inventors: Clifford E. Berkmam, Henry F. Vanbrocklin
  • Rotanone analogs: method of preparation and use
    Patent number: 8551448
    Abstract: The present invention provides rotenone analogs and methods of making and using them. Labeled with single photon and positron emitting isotopes, the rotenone analogs of the present invention are useful in, for example, clinical imaging applications as tracers to measure cardiac blood flow and detect regions of ischemia.
    Type: Grant
    Filed: November 18, 2008
    Date of Patent: October 8, 2013
    Assignee: The Regents of the University of California
    Inventors: Henry F. VanBrocklin, James P. O'Neil, Andrew R. Gibbs, Nandanan Erathodiyil
  • Rotanone Analogs: Method of Preparation and Use
    Publication number: 20090136424
    Abstract: The present invention provides rotenone analogs and methods of making and using them. Labeled with single photon and positron emitting isotopes, the rotenone analogs of the present invention are useful in, for example, clinical imaging applications as tracers to measure cardiac blood flow and detect regions of ischemia.
    Type: Application
    Filed: November 18, 2008
    Publication date: May 28, 2009
    Applicant: The Regents of the University of California
    Inventors: Henry F. VanBrocklin, James P. O'Neil, Andrew R. Gibbs, Nandanan Erathodiyil