Abstract: The present invention relates to methods and neuronal cellular preparations allowing monitoring intracellular and transcellular molecular events on both short and long timescales in an ex vivo neuronal network of intact post-mitotic neurons. In particular, the invention relates to methods, kits, genetically engineered neuronal cells, preparations and uses thereof allowing the ex vivo monitoring of early neuronal disease-related changes in neuronal network behavior.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for organizing trained and untrained neural networks. In one aspect, a neural network device includes a collection of node assemblies interconnected by between-assembly links, each node assembly itself comprising a network of nodes interconnected by a plurality of within-assembly links, wherein each of the between-assembly links and the within-assembly links have an associated weight, each weight embodying a strength of connection between the nodes joined by the associated link, the nodes within each assembly being more likely to be connected to other nodes within that assembly than to be connected to nodes within others of the node assemblies.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for encoding and decoding information. In one aspect, methods of encoding information in an encoder include receiving a signal representing information using a collection of discrete digits, converting, by an encoder, the received signal into a time-based code, and outputting the time-based code. The time-based code is divided into time intervals. Each of the time intervals of the time-based code corresponds to a digit in the received signal. Each digit of a first state of the received signal is expressed as an event occurring at a first time within the corresponding time interval of the time-based code. Each digit of a second state of the received signal is expressed as an event occurring at a second time within the corresponding time intervals of the time-based code, the first time is distinguishable from the second time.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for encoding and decoding information. In one aspect, methods of encoding information in an encoder include the actions of receiving a signal representing information using a collection of discrete digits, converting, by an encoder, the received signal into a time-based code, and outputting the time-based code. The time-based code is divided into time intervals. Each of the time intervals of the time-based code corresponds to a digit in the received signal. Each digit of a first state of the received signal is expressed as a event occurring at a first time within the corresponding time interval of the time-based code. Each digit of a second state of the received signal is expressed as a event occurring at a second time within the corresponding time intervals of the time-based code, the first time is distinguishable from the second time.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for encoding and decoding information. In one aspect, methods of encoding information in an encoder include the actions of receiving a signal representing information using a collection of discrete digits, converting, by an encoder, the received signal into a time-based code, and outputting the time-based code. The time-based code is divided into time intervals. Each of the time intervals of the time-based code corresponds to a digit in the received signal. Each digit of a first state of the received signal is expressed as a event occurring at a first time within the corresponding time interval of the time-based code. Each digit of a second state of the received signal is expressed as a event occurring at a second time within the corresponding time intervals of the time-based code, the first time is distinguishable from the second time.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for encoding and decoding information. In one aspect, methods of encoding information in an encoder include the actions of receiving a signal representing information using a collection of discrete digits, converting, by an encoder, the received signal into a time-based code, and outputting the time-based code. The time-based code is divided into time intervals. Each of the time intervals of the time-based code corresponds to a digit in the received signal. Each digit of a first state of the received signal is expressed as a event occurring at a first time within the corresponding time interval of the time-based code. Each digit of a second state of the received signal is expressed as a event occurring at a second time within the corresponding time intervals of the time-based code, the first time is distinguishable from the second time.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for encoding and decoding information. In one aspect, methods of encoding information in an encoder include the actions of receiving a signal representing information using a collection of discrete digits, converting, by an encoder, the received signal into a time-based code, and outputting the time-based code. The time-based code is divided into time intervals. Each of the time intervals of the time-based code corresponds to a digit in the received signal. Each digit of a first state of the received signal is expressed as a event occurring at a first time within the corresponding time interval of the time-based code. Each digit of a second state of the received signal is expressed as a event occurring at a second time within the corresponding time intervals of the time-based code, the first time is distinguishable from the second time.

Abstract: A technical method for evaluation, publication and distillation of information, such as scientific articles and other similar work, said method, process and system comprising at least the following technical process steps (1) an interactive online reviewing process of said information before it is published; (2) a publication process of said information if accepted; (3) an evaluation process of said information once published; (4) a distillation process of said published information in a tier filtering system based on said evaluation process.

Abstract: A process and apparatus that enable continual self-adaptation of dynamic transmission devices (saSTDs), allow “smart” filtering of information for transmission from one element to another within a network of interacting elements, such as a “neural network”. An adaptation algorithm (MapSA) incorporated in STDs allows multiple parameters of STDs (which determine its filtering properties) to continuously adapt simultaneously and interdependently. In this manner, complex correlations can be established between the parameters in all STDs within a network of interacting elements. The process according to the invention therefore establishes unique patterns of connection parameters within the network which in turn dictates a novel sequence of information processing steps by the network.