Patents by Inventor Henryk M. Stepien

Henryk M. Stepien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biologically active thymones from the thymus
    Patent number: 4374828
    Abstract: A class of three substances has been isolated in highly purified form and in substantially pure form by utilizing thymus tissue as a source material. These three substances are designated thymone A, thymone B and thymone C. Thymones A and B are new peptides which yield approximately 13 and 14 individual amino acid moieties, respectively, on acid hydrolysis. Thymones A and B are chemically characterized by electrophoretic and chromatographic values which are appropriate for substances which are substantially pure. Thymone C was highly purified and its biological activity was reproducibly detected and measured. Thymones A, B and C stimulate the proliferation of lymphocytes. Thymone A stimulates the formation of cyclic adenosine monophosphate. Thymone B stimulates the formation of cyclic guanosine monophosphate.
    Type: Grant
    Filed: November 17, 1980
    Date of Patent: February 22, 1983
    Assignee: Board of Reagents, The University of Texas System
    Inventors: Karl Folkers, Teresa M. Kubiak, Henryk M. Stepien, Naoki Sakura