Patents by Inventor Herbert B. Hechtman

Herbert B. Hechtman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Natural IGM antibodies and inhibitors thereof
    Patent number: 9914751
    Abstract: The invention provides natural IgM antibody inhibitors that may be used to treat various inflammatory diseases or disorders.
    Type: Grant
    Filed: July 23, 2015
    Date of Patent: March 13, 2018
    Assignees: Children's Medical Center Corporation, President and Fellows of Harvard College, The Brigham and Women's Hospital, Inc.
    Inventors: Michael C. Carroll, Francis D. Moore, Jr., Herbert B. Hechtman
  • Natural IGM Antibodies and Inhibitors Thereof
    Publication number: 20170342109
    Abstract: The invention provides natural IgM antibody inhibitors that may be used to treat various inflammatory diseases or disorders.
    Type: Application
    Filed: May 8, 2017
    Publication date: November 30, 2017
    Inventors: Michael C. Carroll, Francis D. Moore, JR., Herbert B. Hechtman
  • Natural IgM antibodies and inhibitors thereof
    Patent number: 9657060
    Abstract: The invention provides natural IgM antibody inhibitors that may be used to treat various inflammatory diseases or disorders.
    Type: Grant
    Filed: April 9, 2013
    Date of Patent: May 23, 2017
    Assignees: Children's Medical Center Corporation, President and Fellows of Harvard College, The Brigham and Women's Hospital, Inc.
    Inventors: Michael C. Carroll, Francis D. Moore, Herbert B. Hechtman
  • NATURAL IGM ANTIBODIES AND INHIBITORS THEREOF
    Publication number: 20160280740
    Abstract: The invention provides natural IgM antibody inhibitors that may be used to treat various inflammatory diseases or disorders.
    Type: Application
    Filed: July 23, 2015
    Publication date: September 29, 2016
    Inventors: Michael C. Carroll, Francis D. Moore, JR., Herbert B. Hechtman
  • Natural IgM Antibodies
    Publication number: 20100136684
    Abstract: The invention provides natural IgM antibodies that may be used to induce inflammatory diseases or disorders such as ischemia-reperfusion injury to create animal models of such inflammatory diseases or disorders.
    Type: Application
    Filed: August 28, 2009
    Publication date: June 3, 2010
    Inventors: Michael C. Carroll, Francis D. Moore, JR., Herbert B. Hechtman
  • Natural IGM Antibodies and Inhibitors Thereof
    Publication number: 20090176966
    Abstract: The invention provides natural IgM antibody inhibitors that may be used to treat various inflammatory diseases or disorders.
    Type: Application
    Filed: October 28, 2008
    Publication date: July 9, 2009
    Inventors: Michael C. Carroll, Francis D. Moore, JR., Herbert B. Hechtman
  • Natural IgM antibodies and inhibitors thereof
    Patent number: 7442783
    Abstract: The invention provides natural IgM antibody inhibitors that may be used to treat various inflammatory diseases or disorders.
    Type: Grant
    Filed: March 1, 2005
    Date of Patent: October 28, 2008
    Assignees: The CBR Institute for Biomedical Research, Inc., President and Fellows of Harvard College, The Brigham and Women's Hospital, Inc.
    Inventors: Michael C. Carroll, Francis D. Moore, Jr., Herbert B. Hechtman
  • Methods and compositions for inhibiting immunoglobulin-mediated reperfusion injury
    Publication number: 20040131607
    Abstract: Methods and compositions for treating or preventing immunoglobulin-mediated reperfusion or ischemic injury, in a subject, are provided. Methods for identifying inhibitors of an interaction between a pathogenic immunoglobulin and ischemic antigen or a component of the complement pathway are provided.
    Type: Application
    Filed: October 6, 2003
    Publication date: July 8, 2004
    Inventors: Michael C. Carroll, Francis D Moore Jr, Herbert B. Hechtman
  • Topical formulations and methods for treating hemorrhoidal pain and sphincter and smooth muscle spasm in the gastrointestinal tract
    Patent number: 5595753
    Abstract: A topical treatment for hemorrhoidal pain and for spasms of the sphincters and muscles located in the gastrointestinal (GI) tract is disclosed. The topical preparation includes the amino acid L-arginine in a pharmaceutically acceptable carrier substance, e.g., K-Y jelly, suppository, or ingestible formulation, and can be applied directly to the affected area. The topical preparation of the invention is effective for relieving the pain of hemorrhoids or for treating conditions resulting from spasms of sphincters of the GI tract including anal fissure, post operative rectal pain, hypertrophic pyloric stenosis, and pancreatitis, as well as conditions resulting from general spasm of the muscles of the GI tract.
    Type: Grant
    Filed: April 14, 1995
    Date of Patent: January 21, 1997
    Assignee: President and Fellows of Harvard College
    Inventor: Herbert B. Hechtman
  • Apparatus for measuring papillary muscle contractility
    Patent number: 4318301
    Abstract: Apparatus for measuring papillary muscle contractility when subjected to electrical stimulus while immersed in a test bathing liquid includes a test chamber for maintaining the liquid at a controlled temperature and having a membrane for diffusion of oxygen into the liquid, arms for mounting a muscle specimen in the liquid, electrodes for providing an electrical stimulus, and a system for measuring the contractile response of the muscle when subjected to electrical stimulus.
    Type: Grant
    Filed: June 23, 1980
    Date of Patent: March 9, 1982
    Assignee: President and Fellows of Harvard College
    Inventors: Richard E. Justice, Gene A. Grindlinger, Herbert B. Hechtman