Patents by Inventor Herbert Bradfield Cunningham

Herbert Bradfield Cunningham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of use of one step immunochromatographic device for A antigen
    Patent number: 7666614
    Abstract: A method to determine the presence or absence of Streptococcus Group A antigen in a sample, comprising the following steps: extracting the antigen from the sample in an assay chamber with two or less extraction reagents, wherein the two reagents may be added to the assay chamber in no particular sequence; introducing a lateral flow immunochromatographic assay device into the extraction reagents containing the extracted antigen without further addition of reagents or manipulation of the sample; forming an antigen-indicator labeling reagent complex; and determining the presence or absence of the antigen in the sample by the presence or absence of a signal formed by the binding of the antigen-indicator labeling reagent complex to an indicator capture reagent specific for said antigen-indicator labeling reagent complex.
    Type: Grant
    Filed: March 2, 2006
    Date of Patent: February 23, 2010
    Assignee: Genzyme Corporation
    Inventors: Shu-Ching Cheng, Ching Huang, Ming-Shian Wu, Michael J. Willrodt, Herbert Bradfield Cunningham, Eugene Fan
  • Methods of use of one step immunochromatographic device for Streptococcus A antigen
    Patent number: 6979576
    Abstract: A method to determine the presence or absence of Streptococcus Group A antigen in a sample, comprising the following steps: extracting the antigen from the sample in an assay chamber with two or less extraction reagents, wherein the two reagents may be added to the assay chamber in no particular sequence; introducing a lateral flow immunochromatographic assay device into the extraction reagents containing the extracted antigen without further addition of reagents or manipulation of the sample; forming an antigen-indicator labeling reagent complex; and determining the presence or absence of the antigen in the sample by the presence or absence of a signal formed by the binding of the antigen-indicator labeling reagent complex to an indicator capture reagent specific for said antigen-indicator labeling reagent complex.
    Type: Grant
    Filed: July 25, 1997
    Date of Patent: December 27, 2005
    Inventors: Shu-Ching Cheng, Ching Huang, Ming-Shian Wu, Michael J. Willrodt, Herbert Bradfield Cunningham, Eugene Fan
  • Hybrid one-step immunochromatographic device and method of use
    Patent number: 6194221
    Abstract: This invention relates to a lateral flow immunochromatographic assay device with an increased range of sensitivity without an increase in the clearance time or the occurrence of false positive results. The indicator reagent for the analyte is located in both a separate labeling reagent region and a discrete zone of the analyte detection region.
    Type: Grant
    Filed: November 3, 1997
    Date of Patent: February 27, 2001
    Assignee: Wyntek Diagnostics, Inc.
    Inventors: Leslie Rehg, Ching Huang, Michael J. Willrodt, Herbert Bradfield Cunningham, Eugene Fan