Abstract: A multilayered tube is provided comprising an inner layer of a tube comprising a first polymer, a second layer of a tube comprising a braided layer comprising a metal or a second polymer, and a third layer of a tube comprising a polymer, which can be either the first, second, or still another third polymer. The braided tube layer provides mechanical strength and rigidity to the multilayered tube without adversely affecting the desired chemical or other properties of the inner and outer layers of the tube. A catheter is provided comprising such a multilayered tube. A method is provided for using a catheter for medical diagnostic or analysis, wherein the catheter comprises such a multilayered tube. A liquid chromatography system is provided comprising tubing which comprises such a multilayered tube.

Abstract: A multilayered tube is provided comprising an inner layer of a tube comprising a first polymer, and a second layer of a tube comprising a second polymer. A catheter is provided comprising a multilayered tube comprising an inner layer of a tube comprising a first polymer, and a second layer of a tube comprising a second polymer. A method is provided for using a catheter for medical diagnostic or analysis, wherein the catheter comprises a multilayered tube comprising an inner layer of a tube comprising a first polymer, and a second layer of a tube comprising a second polymer. A liquid chromatography system is provided comprising tubing which comprises a multilayered tube comprising an inner layer of a tube comprising a first polymer, and a second layer of a tube comprising a second polymer.

Abstract: This invention is a medical device. It is a multipolar catheter assembly optionally in combination with a guidewire. Each of the catheter and the guidewire may be sheathed and have multiple electrodes at their distal ends. Because of their size and flexibility, the catheter and the guidewire may be used at virtually any point within the vasculature particularly, however, within the cardiac arteries or veins, perhaps in conjunction with external electrocardiogram leads, to map the body's electrical activity. When used in the heart, they may be used to determine the source of a cardiac arrythmia. The intimate presence of the guidewire or catheter body in the cardiac vasculature allows the response time to changes in cardiac electrical activity is very quick. The invention is also a method for mapping the electrical activity of the heart by use of one or more of these inventive guidewires or catheters in the cardiac arteries or veins.