Patents by Inventor Herbert H. Wotiz

Herbert H. Wotiz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Specific monoclonal antibodies against a defined epitope of progesterone receptor and methods for their use
    Patent number: 5439796
    Abstract: The present invention provides unique prepared immunogens, site-specific monoclonal antibodies against an epitope of progesterone receptor protein, and an immunoassay to determine the functional integrity of the progesterone receptors in a cellular sample. Collectively or individually the component parts of the invention provide the ability not only to identify accurately the presence of progesterone receptor but also the capability of determining whether the progesterone receptor exists in a clinically normal or abnormal state.
    Type: Grant
    Filed: July 23, 1993
    Date of Patent: August 8, 1995
    Assignee: Trustees of Boston University
    Inventors: Adbulmaged M. Traish, Herbert H. Wotiz
  • Specific antibodies against the DNA-binding domain of and immunoassays to determine the presence and functional status of estrogen receptor proteins
    Patent number: 5389517
    Abstract: The present invention provides unique prepared immunogens, site-specific polyclonal antisera and monoclonal antibodies against the DNA-binding domain of estrogen receptor protein, and immunoassay to determine the functional status of estrogen receptors in a cellular sample. Collectively or individually the component parts of the invention provide the ability not only to identify accurately the presence of human estrogen receptor but also the capability of determining whether the estrogen receptor exists in a functional or non-functional state.
    Type: Grant
    Filed: June 18, 1993
    Date of Patent: February 14, 1995
    Assignee: Trustees of Boston University
    Inventors: Herbert H. Wotiz, Abdulmaged M. Traish
  • Specific antibodies against the DNA-binding domain of and immunoassays to determine the presence and functional status of estrogen receptor proteins
    Patent number: 5312752
    Abstract: The present invention provides unique prepared immunogens, site-specific polyclonal antisera and monoclonal antibodies against the DNA-binding domain of estrogen receptor protein, and immunoassay to determine the functional status of estrogen receptors in a cellular sample. Collectively or individually the component parts of the invention provide the ability not only to identify accurately the presence of human estrogen receptor but also the capability of determining whether the estrogen receptor exists in a functional or non-functional state.
    Type: Grant
    Filed: November 1, 1991
    Date of Patent: May 17, 1994
    Assignee: Trustees of Boston University
    Inventors: Herbert H. Wotiz, Abdulmaged M. Traish
  • Specific monoclonal antibodies against a defined epitope of progesterone receptor and methods for their use
    Patent number: 5283190
    Abstract: The present invention provides unique prepared immunogens, site-specific monoclonal antibodies against an epitope of progesterone receptor protein, and an immunoassay to determine the functional integrity of the progesterone receptors in a cellular sample. Collectively or individually the component parts of the invention provide the ability not only to identify accurately the presence of progesterone receptor but also the capability of determining whether the progesterone receptor exists in a clinically normal or abnormal state.
    Type: Grant
    Filed: September 19, 1991
    Date of Patent: February 1, 1994
    Inventors: Adbulmaged M. Traish, Herbert H. Wotiz