Patents by Inventor Heui Il Kang
Heui Il Kang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9018349Abstract: The present invention relates to a novel process for preparing the aza cyclohexapeptide compound 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N2-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-pneumocandin B0 (caspofungin) represented by the following formula 1, which can improve the problem due to a pungent odor and toxicity during the process and can prepare caspofungin as a final product at high yield compared to conventional processes, and to novel intermediates which are used in the preparation process:Type: GrantFiled: January 12, 2011Date of Patent: April 28, 2015Assignee: CKD Bio Corp.Inventors: Heui-Il Kang, Yun-Beom Ham, Su-Hyun Kyong, Heung-Mo Kang, Tae-Hee Han, Doo-Jin Kang
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Publication number: 20130261286Abstract: The present invention relates to a novel process for preparing the aza cyclohexapeptide compound 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N2-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-pneumocandin B0 (caspofungin) represented by the following formula 1, which can improve the problem due to a pungent odor and toxicity during the process and can prepare caspofungin as a final product at high yield compared to conventional processes, and to novel intermediates which are used in the preparation process:Type: ApplicationFiled: January 12, 2011Publication date: October 3, 2013Applicant: CKD BIO CORP.Inventors: Heui-Il Kang, Yun-Beom Ham, Su-Hyun Kyong, Heung-Mo Kang, Tae-Hee Han, Doo-Jin Kang
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Patent number: 8513277Abstract: The present invention provides novel pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.Type: GrantFiled: November 15, 2011Date of Patent: August 20, 2013Assignee: Yuhan CorporationInventors: Jae-Gyu Kim, Byung-Nak Ahn, Hyouk-Woo Lee, Suk-Won Yoon, Young-Ae Yoon, Dong-Hoon Kim, Se-Hoon Keum, Young-Ah Shin, Heui Il Kang, Sun-Young Jang
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Patent number: 8148529Abstract: The present invention provides novel pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.Type: GrantFiled: September 3, 2005Date of Patent: April 3, 2012Assignee: Yuhan CorporationInventors: Jae-Gyu Kim, Byung-Nak Ahn, Hyouk-Woo Lee, Suk-Won Yoon, Young-Ae Yoon, Dong-Hoon Kim, Se-Hoon Keum, Young-Ah Shin, Heui Il Kang, Ryong Choi, Sun-Young Jang, legal representative
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Publication number: 20120065224Abstract: The present invention provides novel pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.Type: ApplicationFiled: November 15, 2011Publication date: March 15, 2012Applicant: YUHAN CORPORATIONInventors: Jae-Gyu KIM, Byung-Nak AHN, Hyouk-Woo LEE, Suk-Won YOON, Young-Ae YOON, Dong-Hoon KIM, Se-Hoon KEUM, Young-Ah SHIN, Heui-Il KANG, Ryong CHOI, Sun-Young JANG
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Patent number: 7662832Abstract: The present invention provides novel pyrrolo[2,3-c]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[2,3-c]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.Type: GrantFiled: September 3, 2005Date of Patent: February 16, 2010Assignee: Yuhan CorporationInventors: Jae-Gyu Kim, Byung-Nak Ahn, Hyouk-Woo Lee, Suk-Won Yoon, Young-Ae Yoon, Dong-Hoon Kim, Chan-Sun Park, Seok-Hee Han, Myung-Hun Cha, Heui-Il Kang, Sun-Young Jang
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Patent number: 7645450Abstract: Humanized antibodies specifically binding to hTNF-? are prepared from a mouse monoclonal antibody by the CDR (complementarity determining region) grafting method, and they show an antigen binding affinity similar to the original mouse monoclonal antibody and significantly low immunogenicity. Therefore, the humanized antibodies can be effectively used for treating a hTNF-?-related disease such as rheumatoid arthritis, Crohn's disease, psoriatic arthritis, psoriasis, septicemia, asthma, Wegener's granulomatosis, inflammation, and ankylosing spondylitis.Type: GrantFiled: December 29, 2005Date of Patent: January 12, 2010Assignee: Yuhan CorporationInventors: Tae Hyoung Yoo, Moo Young Song, Chang Seok Kim, Sang Koo Park, Kang In Na, Byung Kyu Lee, Heui Il Kang
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Patent number: 7642269Abstract: The present invention provides novel pyrrolo[3,2-b]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[3,2-b]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.Type: GrantFiled: September 3, 2005Date of Patent: January 5, 2010Assignee: Yuhan CorporationInventors: Jae-Gyu Kim, Byung-Nak Ahn, Hyouk-Woo Lee, Suk-Won Yoon, Young-Ae Yoon, Choong-Hyun Lee, Myung-Hun Cha, Heui-Il Kang, Sun-Young Jang
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Patent number: 7541366Abstract: The present invention provides novel pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.Type: GrantFiled: September 3, 2005Date of Patent: June 2, 2009Assignee: YUHAN CorporationInventors: Jae-Gyu Kim, Byung-Nak Ahn, Hyouk-Woo Lee, Suk-Won Yoon, Young-Ae Yoon, Hyun-Ho Choi, Heui-Il Kang
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Publication number: 20090005409Abstract: The present invention provides novel pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.Type: ApplicationFiled: September 3, 2005Publication date: January 1, 2009Applicant: YUHAN CORPORATIONInventors: Jae-Gyu Kim, Byung-Nak Ahn, Hyouk-Woo Lee, Suk-Won Yoon, Young-Ae Yoon, Dong-Hoon Kim, Se-Hoon Keum, Young-Ah Shin, Heui Il Kang, Ryong Choi, Sun-Young Jang
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Patent number: 7435414Abstract: A humanized antibody of the present invention shows similar antigen-binding affinity to a mouse monoclonal antibody and significantly low immunogenecity. Therefore, the humanized antibody of the present invention can be effectively used for treating chronic hepatitis B and preventing HBV infection of a patient received liver transplantation and vertical transmission from a mother infected with HBV to a fetus.Type: GrantFiled: April 7, 2005Date of Patent: October 14, 2008Assignee: Yuhan CorporationInventors: Heui Il Kang, Byung Kyu Lee, Se Cheol Park, Moo Young Song, Tae Hyoung Yoo, Jae Sun Lee, Chang Seok Kim, Sang Koo Park, Kang In Na
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Publication number: 20080008703Abstract: Humanized antibodies specifically binding to hTNF-? are prepared from a mouse monoclonal antibody by the CDR (complementarity determining region) grafting method, and they show an antigen binding affinity similar to the original mouse monoclonal antibody and significantly low immunogenicity. Therefore, the humanized antibodies can be effectively used for treating a hTNF-?-related disease such as rheumatoid arthritis, Crohn's disease, psoriatic arthritis, psoriasis, septicemia, asthma, Wegener's granulomatosis, inflammation, and ankylosing spondylitis.Type: ApplicationFiled: December 29, 2005Publication date: January 10, 2008Inventors: Tae Hyoung Yoo, Moo Young Song, Chang Seok Kim, Sang Koo Park, Kang In Na, Byung Kyu Lee, Heui Il Kang
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Publication number: 20070249658Abstract: The present invention provides novel pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.Type: ApplicationFiled: September 3, 2005Publication date: October 25, 2007Applicant: YUHAN CORPORATIONInventors: Jae-Gyu Kim, Byung-Nak Ahn, Hyouk-Woo Lee, Suk-Won Yoon, Young-Ae Yoon, Hyun-Ho Choi, Heui-Il Kang
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Publication number: 20070219230Abstract: The present invention provides novel pyrrolo[2,3-c]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[2,3-c]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.Type: ApplicationFiled: September 3, 2005Publication date: September 20, 2007Inventors: Jae-Gyu Kim, Byung-Nak Ahn, Hyouk-Woo Lee, Suk-Won Yoon, Young-Ae Yoon, Dong-Hoon Kim, Chan-Sun Park, Seok-Hee Han, Myung-Hun Cha, Heui-Il Kang
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Publication number: 20070213358Abstract: The present invention provides novel pyrrolo[3,2-b]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[3,2-b]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.Type: ApplicationFiled: September 3, 2005Publication date: September 13, 2007Applicant: YUHAN CORPORATIONInventors: Jae-Gyu Kim, Byung-Nak Ahn, Hyouk-Woo Lee, Suk-Won Yoon, Young-Ae Yoon, Choong-Hyun Lee, Myung-Hun Cha, Heui-Il Kang, Sun-Young Jang
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Patent number: 7109320Abstract: An antibody variable region of a monoclonal antibody specifically binding to human tumor necrosis factor-? contains at least one of a heavy chain variable region and a light chain variable region having specific complementarity determining regions therein. A nucleic acid molecule encoding the same, a recombinant vector containing the nucleic acid molecule, and a cell transformed with the recombinant vector are also provided.Type: GrantFiled: November 16, 2004Date of Patent: September 19, 2006Assignee: Yuhan CorporationInventors: Heui Il Kang, In Young Ko, Moo Young Song, Chang Seok Kim, Sang Koo Park, Jae Sun Lee, Tae Hyoung Yoo, Kang In Na