Patents by Inventor Hideaki Shimada

Hideaki Shimada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160272595
    Abstract: The present invention relates to quinazolinone and isoquinolinone derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: October 23, 2014
    Publication date: September 22, 2016
    Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Takeshi MURATA, Sousuke HARA, Satoshi NIIZUMA, Kihito HADA, Hatsuo KAWADA, Masahiro SAKAITANI, Hideaki SHIMADA, Yoshito NAKANISHI
  • Patent number: 9416686
    Abstract: A heat recovery steam generator has a plurality of heat exchangers, including superheaters 28, 30, an evaporator 32 and an economizer 34, disposed in a duct 27 along the flow direction of an exhaust gas 25 from a gas turbine 14, and generates steam by utilizing the exhaust gas 25 from the gas turbine 14. The heat recovery steam generator includes: auxiliary combustors 50, 52, each disposed upstream of one of the heat exchangers, for heating the exhaust gas by means of burners; and an air supply device for supplying air to the burners of the auxiliary combustor 52 from the outside of the duct.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: August 16, 2016
    Assignee: KABUSHIKI KAISHA TOSHIBA
    Inventors: Keiichi Nakamura, Hideaki Shimada
  • Publication number: 20150152047
    Abstract: The present invention relates to benzamide derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: April 24, 2013
    Publication date: June 4, 2015
    Inventors: Takeshi Murata, Satoshi Niizuma, Sousuke Hara, Hatsuo Kawada, Kihito Hada, Hideaki Shimada, Hiroshi Tanaka, Yoshito Nakanishi
  • Publication number: 20150141400
    Abstract: The present invention relates to quinazolinedione derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: April 24, 2013
    Publication date: May 21, 2015
    Inventors: Takeshi Murata, Hatsuo Kawada, Satoshi Niizuma, Sousuke Hara, Kihito Hada, Hideaki Shimada, Hiroshi Tanaka, Toshiyuki Mio
  • Publication number: 20140174053
    Abstract: According to the embodiment of the present invention, there are provided a first stage auxiliary burner configured to heat up the exhaust gas in the upstream side of the superheater, a second stage auxiliary burner configured to heat up the exhaust gas in the upstream side of the evaporator, a fuel supply system configured to distribute fuel so as to be supplied to the first stage auxiliary burner and the second stage auxiliary burner. Distribution of fuel charged to each of the first stage auxiliary burner and the second stage auxiliary burner is controlled in accordance with a predetermined distribution ratio of each charging quantity to whole charging quantity in all the range thereof.
    Type: Application
    Filed: March 26, 2012
    Publication date: June 26, 2014
    Applicant: KABUSHIKI KAISHA TOSHIBA
    Inventors: Keiichi Nakamura, Hideaki Shimada
  • Publication number: 20140130476
    Abstract: An auxiliary burner configured to heat exhaust gas on an upstream side of any one of heat exchangers, and a fuel supply system configured to supply fuel to the auxiliary burner. To avoid damage of a heat-transfer pipe by exhaust gas of high temperature, a reference value on which the restriction on the charging quantity to be supplied to the auxiliary burner is based is set, and the charging quantity of fuel to the auxiliary burner is restricted so as not to exceed a limit defined by the reference value.
    Type: Application
    Filed: March 26, 2012
    Publication date: May 15, 2014
    Applicant: KABUSHIKI KAISHA TOSHIBA
    Inventors: Keiichi Nakamura, Hideaki Shimada
  • Publication number: 20140090356
    Abstract: A heat recovery steam generator has a plurality of heat exchangers, including superheaters 28, 30, an evaporator 32 and an economizer 34, disposed in a duct 27 along the flow direction of an exhaust gas 25 from a gas turbine 14, and generates steam by utilizing the exhaust gas 25 from the gas turbine 14. The heat recovery steam generator includes: auxiliary combustors 50, 52, each disposed upstream of one of the heat exchangers, for heating the exhaust gas by means of burners; and an air supply device for supplying air to the burners of the auxiliary combustor 52 from the outside of the duct.
    Type: Application
    Filed: November 26, 2013
    Publication date: April 3, 2014
    Applicant: KABUSHIKI KAISHA TOSHIBA
    Inventors: Keiichi NAKAMURA, Hideaki Shimada
  • Publication number: 20130032129
    Abstract: The super-abrasive grain fixed type wire saw is equipped with two layers consisting of a brazing material layer (13) and a metal plating layer (16), the aforementioned brazing material layer (13) serving to temporarily fix super-abrasive grains (14), and the aforementioned metal plating layer (16) serving to hold the super-abrasive grains (14). The thickness of the brazing material layer (13) is 10% or less of the average grain diameter of the super-abrasive grains (14). The brazing material layer (13) is formed on the surface of a wire (10) in advance. The super-abrasive grains (14) are dispersed and adhered in a single layer onto the brazing material layer (13). Subsequently, the surface of the brazing material layer (13) is melted and solidified, resulting in a super-abrasive-grains-temporarily-adhered wire (12) such that super-abrasive grains (14) are joined to the adhesion surface of the brazing material layer (13). Thereafter, the super-abrasive-grains-temporarily-adhered wire (12) is metal-plated.
    Type: Application
    Filed: October 29, 2010
    Publication date: February 7, 2013
    Applicant: NAKAMURA CHOKO CO., LTD.,
    Inventors: Yasuhiko Otani, Tsutomu Tomiyoshi, Yoshihiro Hagihara, Kenji Kubo, Hiroaki Inoue, Toshihide Takagi, Hideaki Shimada, Masahito Fukumoto, Kazuhiro Shimono
  • Patent number: 7998693
    Abstract: The present invention provides a new additional identification of a gene related to cancer expression and a diagnostic kit using the same.
    Type: Grant
    Filed: January 5, 2006
    Date of Patent: August 16, 2011
    Assignee: National University Corporation Chiba University
    Inventors: Hideaki Shimada, Takeshi Tomonaga, Kazuyuki Matsushita, Takenori Ochiai, Fumio Nomura
  • Patent number: 7897562
    Abstract: An object of the present invention is to provide a novel means for stably and surely inducing cell apoptosis using the c-myc gene as a target. The present invention relates to an apoptosis-inducing agent containing a protein that interacts with an FBP protein or a polynucleotide encoding the protein as an active ingredient and a method for inducing apoptosis, which comprises a step of causing the apoptosis-inducing agent to come into contact with cells.
    Type: Grant
    Filed: January 25, 2008
    Date of Patent: March 1, 2011
    Assignee: National University Corporation Chiba University
    Inventors: Hideaki Shimada, Kazuyuki Matsushita, Takeshi Tomonaga, Fumio Nomura, Takenori Ochiai
  • Patent number: 7781180
    Abstract: Using the protein chip technology, biological samples such as sera are subjected to proteome analysis. Thus, a protein which is a human fibrinogen ?-E chain decomposition product and has a molecular weight of 5,900, a protein which is an apolipoprotein AII decomposition product and has a molecular weight of 7,800, and a protein which is an apolipoprotein AI decomposition product and has a molecular weight of 28,000, each showing an increase or a decrease with the habit of drinking, are newly found out. By detecting or quantifying these proteins, a liver disease in a subject such as one having a problem of drinking can be diagnosed at the early stage.
    Type: Grant
    Filed: March 4, 2009
    Date of Patent: August 24, 2010
    Assignee: Nitto Boseki Co., Ltd.
    Inventors: Fumio Nomura, Kazuyuki Sogawa, Takeshi Tomonaga, Takenori Ochiai, Hideaki Shimada, Tatsuya Ohashi, Katsuhiro Katayama
  • Publication number: 20100196928
    Abstract: The present invention provides a new additional identification of a gene related to cancer expression and a diagnostic kit using the same.
    Type: Application
    Filed: January 5, 2006
    Publication date: August 5, 2010
    Applicant: NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY
    Inventors: Hideaki Shimada, Takeshi Tomonaga, Kazuyuki Matsushita, Takenori Ochiai, Fumio Nomura
  • Publication number: 20090275059
    Abstract: Using the protein chip technology, biological samples such as sera are subjected to proteome analysis. Thus, a protein which is a human fibrinogen ?-E chain decomposition product and has a molecular weight of 5,900, a protein which is an apolipoprotein AII decomposition product and has a molecular weight of 7,800, and a protein which is an apolipoprotein AI decomposition product and has a molecular weight of 28,000, each showing an increase or a decrease with the habit of drinking, are newly found out. By detecting or quantifying these proteins, a liver disease in a subject such as one having a problem of drinking can be diagnosed at the early stage.
    Type: Application
    Filed: March 4, 2009
    Publication date: November 5, 2009
    Applicant: NITTO BOSEKI CO., LTD.
    Inventors: Fumio Nomura, Kazuyuki Sogawa, Takeshi Tomonaga, Takenori Ochiai, Hideaki Shimada, Tatsuya Ohashi, Katsuhiro Katayama
  • Patent number: 7517951
    Abstract: Using the protein chip technology, biological samples such as sera are subjected to proteome analysis. Thus, a protein which is a human fibrinogen ?-E chain decomposition product and has a molecular weight of 5,900, a protein which is an apolipoprotein AII decomposition product and has a molecular weight of 7,800, and a protein which is an apolipoprotein AI decomposition product and has a molecular weight of 28,000, each showing an increase or a decrease with the habit of drinking, are newly found out. By detecting or quantifying these proteins, a liver disease in a subject such as one having a problem of drinking can be diagnosed at the early stage.
    Type: Grant
    Filed: December 24, 2003
    Date of Patent: April 14, 2009
    Assignee: Nitto Boseki Co., Ltd.
    Inventors: Fumio Nomura, Kazuyuki Sogawa, Takeshi Tomonaga, Takenori Ochiai, Hideaki Shimada, Tatsuya Ohashi, Katsuhiro Katayama
  • Publication number: 20080227705
    Abstract: An object of the present invention is to provide a novel means for stably and surely inducing cell apoptosis using the c-myc gene as a target. The present invention relates to an apoptosis-inducing agent containing a protein that interacts with an FBP protein or a polynucleotide encoding the protein as an active ingredient and a method for inducing apoptosis, which comprises a step of causing the apoptosis-inducing agent to come into contact with cells.
    Type: Application
    Filed: January 25, 2008
    Publication date: September 18, 2008
    Applicant: Japan Science and Technology Agency
    Inventors: Hideaki Shimada, Kazuyuki Matsushita, Takeshi Tomonaga, Fumio Nomura, Takenori Ochiai
  • Publication number: 20060199946
    Abstract: An object of the present invention is to provide a novel means for stably and surely inducing cell apoptosis using the c-myc gene as a target. The present invention relates to an apoptosis-inducing agent containing a protein that interacts with an FBP protein or a polynucleotide encoding the protein as an active ingredient and a method for inducing apoptosis, which comprises a step of causing the apoptosis-inducing agent to come into contact with cells.
    Type: Application
    Filed: March 30, 2004
    Publication date: September 7, 2006
    Inventors: Hideaki Shimada, Kazuyuki Matsushita, Takeshi Tomonaga, Fumio Nomura, Takenori Ochiai
  • Publication number: 20060116504
    Abstract: Using the protein chip technology, biological samples such as sera are subjected to proteome analysis. Thus, a protein which is a human fibrinogen ?-E chain decomposition product and has a molecular weight of 5,900, a protein which is an apolipoprotein AII decomposition product and has a molecular weight of 7,800, and a protein which is an apolipoprotein AI decomposition product and has a molecular weight of 28,000, each showing an increase or a decrease with the habit of drinking, are newly found out. By detecting or quantifying these proteins, a liver disease in a subject such as one having a problem of drinking can be diagnosed at the early stage.
    Type: Application
    Filed: December 24, 2003
    Publication date: June 1, 2006
    Applicant: Nitto Boseki Co., Ltd.
    Inventors: Fumio Nomura, Kazuyuki Sogawa, Takeshi Tomonaga, Takenori Ochiai, Hideaki Shimada, Tatsuya Oshashi, Katsuhiro Katayama
  • Patent number: 6553008
    Abstract: A multidirectional time-division multiplexing wireless data communications system can prevent erroneous data from being transmitted through a data communication line even when a bit error has occurred in transmission data. An error correcting redundant bit, obtained by performing an error correcting code operation on a low-speed continuous signal, is multiplexed to a specific vacant slot in a wireless frame. A burst signal, converted by a continuous/burst signal conversion circuit through an interleaving operation, is multiplexed to a predetermined time slot, and transmitted to a wireless area. The burst signal is received by the conversion circuit, and converted into a continuous signal through a de-interleaving operation. A division circuit divides an error correcting code to generate a syndrome. Based on the syndrome, an error position detection circuit specifies bit error position in data, and an addition circuit corrects errors.
    Type: Grant
    Filed: January 19, 1999
    Date of Patent: April 22, 2003
    Assignee: NEC Corporation
    Inventor: Hideaki Shimada
  • Patent number: 6435138
    Abstract: An exhaust heat recovery boiler in which an exhaust gas discharged from a gas turbine into a boiler duct to recover a heat of the exhaust gas and ammonia is injected to and mixed with the exhaust gas to reduce nitrogen oxide contained in the exhaust gas, the exhaust heat recovery boiler comprising: a boiler duct of a horizontal installation type having an inner hollow portion along which an exhaust gas flows from an upstream side to a downstream side; a superheater; an evaporator; a denitration reactor; and an economizer, which are disposed inside the boiler duct in this order from the upstream side to the downstream side of the exhaust gas flow therein. A drum is disposed outside the boiler duct and connected to the evaporator and a downcomer pipe extending from the drum into the boiler duct.
    Type: Grant
    Filed: June 28, 2001
    Date of Patent: August 20, 2002
    Assignee: Kabushiki Kaisha Toshiba
    Inventors: Hideaki Shimada, Norihide Egami, Takayuki Nagashima
  • Patent number: D570009
    Type: Grant
    Filed: October 25, 2007
    Date of Patent: May 27, 2008
    Assignee: PIAA Corporation
    Inventors: Gen Kani, Yukari Ishiwatari, Hideaki Shimada