Patents by Inventor Hideharu SHICHI
Hideharu SHICHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230241713Abstract: An apparatus for emitting an incident laser beam that is a linearly polarized laser beam at a predetermined intensity, includes: an intensity changing optical element (polarization beam splitter) disposed on the optical path of the incident laser beam, for changing the intensity of an outgoing laser beam by allowing a transmission of a component of the incident laser beam polarized in a predetermined variable transmission direction and to rotate around the optical axis of the incident laser beam within a range of at least 90° with respect to a predetermined reference angle; and a polarization direction changing optical element (concave lens) disposed upstream the optical path of the incident laser beam with respect to the intensity changing optical element, and for changing the polarization direction of the incident laser beam and to emit the incident laser beam, the change direction being variable.Type: ApplicationFiled: February 26, 2021Publication date: August 3, 2023Applicant: SHIMADZU CORPORATIONInventor: Hideharu SHICHI
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Patent number: 11527393Abstract: A spectrum acquirer acquires a plurality of mass spectrums. A specific physical quantity calculator calculates a specific physical quantity reflecting an amount of ions with respect to each of the plurality of obtained mass spectrums. A spectrum sorter sorts the plurality of mass spectrums in order of the specific physical quantity calculated with respect to each mass spectrum. A display controller allows a display to display the plurality of sorted mass spectrums. A spectrum selector selects a plurality of mass spectrums having specific physical quantities in a designated range from the plurality of displayed mass spectrums. A post-selection spectrum integrator integrates the plurality of selected mass spectrums. The display controller allows the display to display the post-selection integrated mass spectrum.Type: GrantFiled: October 11, 2019Date of Patent: December 13, 2022Assignee: Shimadzu CorporationInventor: Hideharu Shichi
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Patent number: 11164732Abstract: The mass spectrometer includes an ionizer, a mass separator, a detection device, a storage, and a controller. The detection device includes a detector and an electron introducer. The electrons from the electron introducer are introduced into the detector. In addition to an analysis operation, the mass spectrometer performs an operation to determine a voltage applied to the detector. At this point, electrons are introduced from the electron introducer to the detector. In the case that a detection value from the detector is less than a threshold, the controller can determine that a defect such as aging is generated in the detector.Type: GrantFiled: March 6, 2019Date of Patent: November 2, 2021Assignee: SHIMADZU CORPORATIONInventor: Hideharu Shichi
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Patent number: 11139154Abstract: The invention provides a matrix observation device where a location to be irradiated with a laser beam that provides high efficiency of the ionization can be found from among sample spots arranged on a sample plate. The device is formed of: a stage 31 on which a sample plate 20 on which a sample is to be arranged is to be placed; a light source unit 40 that emits ultraviolet rays for observation with which the sample plate 20 is irradiated; and an image acquisition unit 50 for detecting light from the sample plate 20 so as to create an optical image, and the sample contains a matrix that absorbs the ultraviolet rays for observation.Type: GrantFiled: February 4, 2019Date of Patent: October 5, 2021Assignee: Shimadzu CorporationInventors: Kei Kodera, Hideharu Shichi
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Publication number: 20210257203Abstract: In a MALDI ion source (1), laser light from a laser light source (2) is reflected by a mirror (5), and then energy of the laser light is adjusted by a polarization beam splitter (6). Then, the laser light of which the energy has been adjusted is applied toward a sample. The polarization beam splitter (6) is rotated to adjust the energy of the laser light. Therefore, in the MALDI ion source (1), it is possible to adjust the energy of the laser light and apply the laser light to the sample only by providing the rotatable polarization beam splitter (6).Type: ApplicationFiled: January 25, 2019Publication date: August 19, 2021Applicant: SHIMADZU CORPORATIONInventor: Hideharu SHICHI
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Patent number: 10971349Abstract: An ion analyzer includes: a sample placement unit 2 on which a sample 1 is to be placed; an excitation beam irradiation unit 3 that irradiates the sample 1 placed on the sample placement unit 2 with an excitation beam in a direction perpendicular to a surface of the sample 1; a deflection unit 6 that makes at least some of ions generated from the sample 1 to fly in a direction deviating from an irradiation path of the excitation beam; and an analysis unit 8 disposed in a flight direction of ions deflected by the deflection unit 6, that separates and measures the ions in accordance with a predetermined physical quantity.Type: GrantFiled: November 18, 2016Date of Patent: April 6, 2021Assignee: Shimadzu CorporationInventors: Kei Kodera, Kosuke Hosoi, Hideharu Shichi
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Patent number: 10964516Abstract: A mass spectrometer includes an ion source that generates ions, an ion trap that captures the ions generated from the ion source, a detector that detects the ions ejected from the ion trap and a controller that controls a periodic voltage, which is added to form a capturing electric field in the ion trap and controls a time point at which the ions are generated from the ion source. The controller includes an ion generation time controller that allows the ions to be generated from the ion source at N (N is an integer equal to or larger than 2) phase time points while addition of the periodic voltage is continued, the N phase time points being set in one period of the periodic voltage and being respectively assigned to different periods of the periodic voltage.Type: GrantFiled: October 10, 2019Date of Patent: March 30, 2021Assignee: SHIMADZU CORPORATIONInventor: Hideharu Shichi
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Patent number: 10923337Abstract: An ion source of an ion trap mass spectrometer generates ions of a component in a sample. An ion trap captures the ions generated by the ion source. An ion detector detects ions ejected from the ion trap. A voltage application control part changes a voltage applied to the ion detector such that, after generation of ions by the ion source is started, ion detection capability of the ion detector during a time period when ions having a mass-to-charge ratio outside an analysis target range are ejected from the ion trap is lower as compared to ion detection capability of the ion detector during a time period when ions having a mass-to-charge ratio within the analysis target range are ejected from the ion trap.Type: GrantFiled: October 11, 2019Date of Patent: February 16, 2021Assignee: Shimadzu CorporationInventor: Hideharu Shichi
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Publication number: 20200251321Abstract: The invention provides a matrix observation device where a location to be irradiated with a laser beam that provides high efficiency of the ionization can be found from among sample spots arranged on a sample plate. The device is formed of: a stage 31 on which a sample plate 20 on which a sample is to be arranged is to be placed; a light source unit 40 that emits ultraviolet rays for observation with which the sample plate 20 is irradiated; and an image acquisition unit 50 for detecting light from the sample plate 20 so as to create an optical image, and the sample contains a matrix that absorbs the ultraviolet rays for observation.Type: ApplicationFiled: February 4, 2019Publication date: August 6, 2020Inventors: Kei KODERA, Hideharu SHICHI
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Publication number: 20200185208Abstract: An ion source of an ion trap mass spectrometer generates ions of a component in a sample. An ion trap captures the ions generated by the ion source. An ion detector detects ions ejected from the ion trap. A voltage application control part changes a voltage applied to the ion detector such that, after generation of ions by the ion source is started, ion detection capability of the ion detector during a time period when ions having a mass-to-charge ratio outside an analysis target range are ejected from the ion trap is lower as compared to ion detection capability of the ion detector during a time period when ions having a mass-to-charge ratio within the analysis target range are ejected from the ion trap.Type: ApplicationFiled: October 11, 2019Publication date: June 11, 2020Applicant: Shimadzu CorporationInventor: Hideharu SHICHI
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Publication number: 20200185206Abstract: A spectrum acquirer acquires a plurality of mass spectrums. A specific physical quantity calculator calculates a specific physical quantity reflecting an amount of ions with respect to each of the plurality of obtained mass spectrums. A spectrum sorter sorts the plurality of mass spectrums in order of the specific physical quantity calculated with respect to each mass spectrum. A display controller allows a display to display the plurality of sorted mass spectrums. A spectrum selector selects a plurality of mass spectrums having specific physical quantities in a designated range from the plurality of displayed mass spectrums. A post-selection spectrum integrator integrates the plurality of selected mass spectrums. The display controller allows the display to display the post-selection integrated mass spectrum.Type: ApplicationFiled: October 11, 2019Publication date: June 11, 2020Applicant: Shimadzu CorporationInventor: Hideharu Shichi
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Publication number: 20200161113Abstract: A mass spectrometer includes an ion source that generates ions, an ion trap that captures the ions generated from the ion source, a detector that detects the ions ejected from the ion trap and a controller that controls a periodic voltage, which is added to form a capturing electric field in the ion trap and controls a time point at which the ions are generated from the ion source. The controller includes an ion generation time controller that allows the ions to be generated from the ion source at N (N is an integer equal to or larger than 2) phase time points while addition of the periodic voltage is continued, the N phase time points being set in one period of the periodic voltage and being respectively assigned to different periods of the periodic voltage.Type: ApplicationFiled: October 10, 2019Publication date: May 21, 2020Applicant: SHIMADZU CORPORATIONInventor: Hideharu SHICHI
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Publication number: 20190362954Abstract: The mass spectrometer includes an ionizer, a mass separator, a detection device, a storage, and a controller. The detection device includes a detector and an electron introducer. The electrons from the electron introducer are introduced into the detector. In addition to an analysis operation, the mass spectrometer performs an operation to determine a voltage applied to the detector. At this point, electrons are introduced from the electron introducer to the detector. In the case that a detection value from the detector is less than a threshold, the controller can determine that a defect such as aging is generated in the detector.Type: ApplicationFiled: March 6, 2019Publication date: November 28, 2019Applicant: SHIMADZU CORPORATIONInventor: Hideharu SHICHI
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Publication number: 20190279857Abstract: An ion analyzer includes: a sample placement unit 2 on which a sample 1 is to be placed; an excitation beam irradiation unit 3 that irradiates the sample 1 placed on the sample placement unit 2 with an excitation beam in a direction perpendicular to a surface of the sample 1; a deflection unit 6 that makes at least some of ions generated from the sample 1 to fly in a direction deviating from an irradiation path of the excitation beam; and an analysis unit 8 disposed in a flight direction of ions deflected by the deflection unit 6, that separates and measures the ions in accordance with a predetermined physical quantity.Type: ApplicationFiled: November 18, 2016Publication date: September 12, 2019Inventors: Kei KODERA, Kosuke HOSOI, Hideharu SHICHI