Abstract: Provided are a method of producing canine iPS cells, comprising (a) the step of bringing into contact with each other a canine somatic cell and a nuclear reprogramming factor, and (b) the step of culturing the cell in a medium containing at least one substance selected from the group consisting of a mitogen-activated protein kinase kinase inhibitor, an activin receptor-like kinase inhibitor, a glycogen synthase kinase inhibitor, a L-type calcium channel agonist and a DNA methylation inhibitor, and a leukemia inhibitory factor, and canine iPS cells that can be obtained by the method.

Abstract: Provided are a method of producing canine iPS cells, comprising (a) the step of bringing into contact with each other a canine somatic cell and a nuclear reprogramming factor, and (b) the step of culturing the cell in a medium containing at least one substance selected from the group consisting of a mitogen-activated protein kinase kinase inhibitor, an activin receptor-like kinase inhibitor, a glycogen synthase kinase inhibitor, a L-type calcium channel agonist and a DNA methylation inhibitor, and a leukemia inhibitory factor, and canine iPS cells that can be obtained by the method.

Abstract: This laser beam processing apparatus includes a fiber laser oscillator, a laser beam branching unit, a laser beam injecting unit, a fiber transmission system, a laser beam irradiating unit, and a processing table. Based on a fiber laser beam, which is oscillation-outputted from the fiber laser oscillator, the laser beam branching unit executes simultaneous multi-branching from the fiber laser beam into a plurality of branched laser beams. The laser beam injecting unit injects the branched laser beams respectively into optical fibers for transmission and the laser beam irradiating units condense and apply the branched laser beams from the optical fibers for transmission respectively to processing points.

Abstract: This laser beam processing apparatus includes a fiber laser oscillator, a laser beam branching unit, a laser beam injecting unit, a fiber transmission system, a laser beam irradiating unit, and a processing table. Based on a fiber laser beam, which is oscillation-outputted from the fiber laser oscillator, the laser beam branching unit executes simultaneous multi-branching from the fiber laser beam into a plurality of branched laser beams. The laser beam injecting unit injects the branched laser beams respectively into optical fibers for transmission and the laser beam irradiating units condense and apply the branched laser beams from the optical fibers for transmission respectively to processing points.

Abstract: This laser beam processing apparatus includes a fiber laser oscillator, a laser beam branching unit, a laser beam injecting unit, a fiber transmission system, a laser beam irradiating unit, and a processing table. Based on a fiber laser beam, which is oscillation-outputted from the fiber laser oscillator, the laser beam branching unit executes simultaneous multi-branching from the fiber laser beam into a plurality of branched laser beams. The laser beam injecting unit injects the branched laser beams respectively into optical fibers for transmission and the laser beam irradiating units condense and apply the branched laser beams from the optical fibers for transmission respectively to processing points.

Abstract: A fiber laser beam processing apparatus is configured by a fiber laser oscillator, a laser power source unit, a laser beam injecting unit, a fiber transmission system, a laser beam irradiating unit, a processing table, etc. A portion of a fiber laser beam oscillated and outputted by the fiber laser oscillator is received by a photo diode for monitoring the power through a beam splitter. An output signal of the photo diode is sent to a laser power source unit. The power source unit receives the output signal of the photo diode as a feedback signal and controls a driving current or an excitation current to be supplied to a laser diode of a pumping unit such that the laser output of the fiber laser beam equals a set value.

Abstract: The fiber laser beam processing apparatus includes a fiber laser oscillator, a laser power source unit, a laser injecting unit, a fiber transmission system, a laser beam irradiating unit, a processing table, etc. The fiber laser oscillator includes an optical fiber for oscillation, an electric optical pumping unit that applies an excitation beam for optical pumping onto an end face of the optical fiber for oscillation, and a pair of optical resonator mirrors optically facing each other through the optical fiber for oscillation. The optical fiber for oscillation includes a core extending on the central axis thereof, a clad surrounding the core, an air layer surrounding the clad, and a support surrounding and supporting the air layer.

Abstract: An end cap is formed as a substantially cylindrical body having substantially the same diameter as an external diameter of a retaining unit of an oscillation fiber; a base end surface is integrally fusion-welded or fusion-bonded to one end surface of the oscillation fiber; and a leading end surface is obliquely cut relative to the light axis. A returning oscillating beam reflected by an optical resonator mirror is converged and made incident on a core end surface of the oscillation fiber 22 located at a focus position of an optical lens. However, since the core end surface is integrally bonded with the end cap and is not exposed to the atmosphere, the core end surface is not burned or deteriorated by the light energy of the oscillating beam.

Abstract: One end of an optical fiber for oscillation is held in a holding groove having a V-shaped section, which holding groove is formed on the upper face of a lower block. On an upper block, a slit is formed in the place that is counter to the holding groove of the lower block. A sapphire rod can be inserted from above into the slit, and is guided vertically in a slidable manner in the slit. The sapphire rod is brought in contact with the upper face of the optical fiber for oscillation, and is supported to be slidable over both side inner wall surfaces at the lower end of the slit. An extent of screwing of bolt is changed to adjust a spring pressure of a compressive coil spring, that is, a press force against the optical fiber for oscillation.

Abstract: An end cap is formed as a substantially cylindrical body having substantially the same diameter as an external diameter of a retaining unit of an oscillation fiber; a base end surface is integrally fusion-welded or fusion-bonded to one end surface of the oscillation fiber; and a leading end surface is obliquely cut relative to the light axis. A returning oscillating beam reflected by an optical resonator mirror is converged and made incident on a core end surface of the oscillation fiber 22 located at a focus position of an optical lens. However, since the core end surface is integrally bonded with the end cap and is not exposed to the atmosphere, the core end surface is not burned or deteriorated by the light energy of the oscillating beam.

Abstract: The fiber laser beam processing apparatus includes a fiber laser oscillator, a laser power source unit, a laser injecting unit, a fiber transmission system, a laser beam irradiating unit, a processing table, etc. The fiber laser oscillator includes an optical fiber for oscillation, an electric optical pumping unit that applies an excitation beam for optical pumping onto an end face of the optical fiber for oscillation, and a pair of optical resonator mirrors optically facing each other through the optical fiber for oscillation. The optical fiber for oscillation includes a core extending on the central axis thereof, a clad surrounding the core, an air layer surrounding the clad, and a support surrounding and supporting the air layer.

Abstract: This laser beam processing apparatus includes a fiber laser oscillator, a laser beam branching unit, a laser beam injecting unit, a fiber transmission system, a laser beam irradiating unit, a processing table, etc. Based on a fiber laser beam oscillation-outputted from the fiber laser oscillator, the laser beam branching unit executes simultaneous multi-branching from the fiber laser beam into a plurality of branched laser beams. The laser beam injecting unit injects the branched laser beams respectively into optical fibers for transmission and the laser beam irradiating units condense and apply the branched laser beams from the optical fibers for transmission respectively to processing points.

Abstract: A fiber laser beam processing apparatus is configured by a fiber laser oscillator, a laser power source unit, a laser beam injecting unit, a fiber transmission system, a laser beam irradiating unit, a processing table, etc. A portion of a fiber laser beam oscillated and outputted by the fiber laser oscillator is received by a photo diode for monitoring the power through a beam splitter. An output signal of the photo diode is sent to a laser power source unit. The power source unit receives the output signal of the photo diode as a feedback signal and controls a driving current or an excitation current to be supplied to a laser diode of a pumping unit such that the laser output of the fiber laser beam equals a set value.