Patents by Inventor Hideo Terayama

Hideo Terayama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6683070
    Abstract: The aqueous suspension can be prepared by incorporating, in an aqueous suspension of a hardly soluble drug, a water-soluble polymer within the concentration range from the concentration at which the surface tension of the aqueous suspension of the drug begins to decrease up to the concentration at which the reduction in surface tension ceases. The resulting aqueous suspension shows ready redispersibility and will not undergo aggregation of dispersed particles or caking. Because of its good redispersibility, the suspension is useful as a parenteral preparation, eye drops, nasal drops, a preparation for oral administration, a lotion or the like.
    Type: Grant
    Filed: July 8, 2002
    Date of Patent: January 27, 2004
    Assignee: Senju Pharmaceutical Co., Ltd.
    Inventors: Shin-ichi Yasueda, Keiichi Matsuhisa, Hideo Terayama, Katsuhiro Inada
  • Publication number: 20030008010
    Abstract: The aqueous suspension can be prepared by incorporating, in an aqueous suspension of a hardly soluble drug, a water-soluble polymer within the concentration range from the concentration at which the surface tension of the aqueous suspension of the drug begins to decrease up to the concentration at which the reduction in surface tension ceases. The resulting aqueous suspension shows ready redispersibility and will not undergo aggregation of dispersed particles or caking. Because of its good redispersibility, the suspension is useful as a parenteral preparation, eye drops, nasal drops, a preparation for oral administration, a lotion or the like.
    Type: Application
    Filed: July 8, 2002
    Publication date: January 9, 2003
    Inventors: Shin-Ichi Yasueda, Keiichi Matsuhisa, Hideo Terayama, Katsuhiro Inada
  • Patent number: 6448296
    Abstract: The aqueous suspension can be prepared by incorporating, in an aqueous suspension of a hardly soluble drug, a water-soluble polymer within the concentration range from the concentration at which the surface tension of the aqueous suspension of the drug begins to decrease up to the concentration at which the reduction in surface tension ceases. The resulting aqueous suspension shows ready redispersibility and will not undergo aggregation of dispersed particles or caking. Because of its good redispersibility, the suspension is useful as a parenteral preparation, eye drops, nasal drops, a preparation for oral administration, a lotion or the like.
    Type: Grant
    Filed: June 5, 2001
    Date of Patent: September 10, 2002
    Assignee: Senju Pharmaceutical Co., Ltd.
    Inventors: Shin-ichi Yasueda, Keiichi Matsuhisa, Hideo Terayama, Katsuhiro Inada
  • Publication number: 20010036966
    Abstract: The aqueous suspension can be prepared by incorporating, in an aqueous suspension of a hardly soluble drug, a water-soluble polymer within the concentration range from the concentration at which the surface tension of the aqueous suspension of the drug begins to decrease up to the concentration at which the reduction in surface tension ceases. The resulting aqueous suspension shows ready redispersibility and will not undergo aggregation of dispersed particles or caking. Because of its good redispersibility, the suspension is useful as a parenteral preparation, eye drops, nasal drops, a preparation for oral administration, a lotion or the like.
    Type: Application
    Filed: June 5, 2001
    Publication date: November 1, 2001
    Inventors: Shin-Ichi Yasueda, Keiichi Matsuhisa, Hideo Terayama, Katsuhiro Inada
  • Patent number: 6274634
    Abstract: The aqueous suspension can be prepared by incorporating, in an aqueous suspension of a hardly soluble drug, a water-soluble polymer within the concentration range from the concentration at which the surface tension of the aqueous suspension of the drug begins to decrease up to the concentration at which the reduction in surface tension ceases. The resulting aqueous suspension shows ready redispersibility and will not undergo aggregation of dispersed particles or caking. Because of its good redispersibility, the suspension is useful as a parenteral preparation, eye drops, nasal drops, a preparation for oral administration, a lotion or the like.
    Type: Grant
    Filed: November 10, 1999
    Date of Patent: August 14, 2001
    Assignee: Senju Pharmaceutical Co., Ltd.
    Inventors: Shin-ichi Yasueda, Keiichi Matsuhisa, Hideo Terayama, Katsuhiro Inada
  • Patent number: 5916550
    Abstract: The conventional aqueous suspension of loteprednol etabonate is not easily amenable to production pH control and entails a pH depression on long-term storage, thus irritating the eye or the nasal mucosa on instillation.When a C2-7 aliphatic amino acid is added to an aqueous suspension of loteprednol etabonate for topical ophthalmic use, the suspension does not undergo pH depression even on prolonged storage, with the result that no irritable response is elicited in the eye or nasal mucosa.
    Type: Grant
    Filed: March 5, 1998
    Date of Patent: June 29, 1999
    Assignee: Senju Pharmaceutical Co., Ltd.
    Inventors: Katsuhiro Inada, Hideo Terayama
  • Patent number: 4822823
    Abstract: This invention relates to an aqueous preparation comprising a compound (A) represented by the formula: ##STR1## and at least one of cyclodextrins selected from .alpha.-cyclodextrin and dimethyl-.beta.-cyclodextrin; and a method of preparation thereof.According to the aqueous preparation of this invention, coexistence with at least one medicament selected from .alpha.-cyclodextrin and dimethyl-.beta.-cyclodextrin allows to enhance the solubility to water of compound (A) essential in this invention to such a concentration that makes an expected curative effect available and to inpart a desired stability to it. As a consequence, the aforesaid compound (A) can be utilized as a medicament for an aqueous preparation having anti-allergy action.
    Type: Grant
    Filed: February 3, 1987
    Date of Patent: April 18, 1989
    Assignee: Senju Pharmaceutical Co., Ltd.
    Inventors: Yujiro Yamamoto, Hideo Terayama, Yasushi Morita
  • Patent number: 4820837
    Abstract: The compounds represented by the general formula ##STR1## wherein R is an alkyl group having 1-10 carbon atoms are novel compounds which have not been reported in the literature. Since they have excellent affinities for tissues with particular high corneal permeability and show anticataract activity at low concentration, the compounds are of value as prophylactic and therapeutic agents for cataracts.
    Type: Grant
    Filed: June 30, 1987
    Date of Patent: April 11, 1989
    Assignee: Senju Pharmaceutical Co., Ltd.
    Inventors: Hideo Terayama, Jun Inoue
  • Patent number: 4780465
    Abstract: A stable isotonic aqueous solution of the compound 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxoquinoline -3-carboxylic acid, or a pharmaceutically-acceptable salt thereof, having a pH of 3 to 6.5 and isotonized with a polyalcohol or boric acid is disclosed.
    Type: Grant
    Filed: May 20, 1987
    Date of Patent: October 25, 1988
    Assignee: Hokuriku Pharmaceutical Co., Ltd.
    Inventors: Kazumi Ogata, Hideo Terayama, Satoshi Takei
  • Patent number: 4728509
    Abstract: In the aqueous liquid preparation of this invention, which comprises a compound of the formula; ##STR1## wherein R is an alkyl having 1-6 carbon atoms, and at least one species of the solubilizers selected from the group consisting of polyvinylpyrrolidone, cyclodextrin and caffeine, the solubility of the compound in water can be heightened and the aqueous liquid prepared thereby can afford a desired stability and mitigate eye-irritation or nose-irritation.
    Type: Grant
    Filed: August 5, 1986
    Date of Patent: March 1, 1988
    Assignees: Takeda Chemical Industries, Ltd., Senju Pharmaceutical Co., Ltd.
    Inventors: Hisayoshi Shimizu, Mitsuaki Oshima, Hideo Terayama