Patents by Inventor Hideo Tsukada

Hideo Tsukada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11976619
    Abstract: A movable core is driven by a magnetic attraction force with a fixed core to move a valve body to inject fuel. A yoke accommodates the fixed core. A coil is in a coil chamber between the fixed core and the yoke. The coil chamber is filled with a filling resin member being electrically insulative. The fixed core has a core facing surface facing the movable core and includes a protruding portion that protrudes radially outer side and is in contact with the yoke to conduct the magnetic flux. A resin molding flow channel is formed in the protruding portion to cause molten resin serving as the filling resin member to flow into the coil chamber. A length of the protruding portion along a cylinder center line is set to be shorter toward a radially outer side.
    Type: Grant
    Filed: July 15, 2021
    Date of Patent: May 7, 2024
    Assignee: DENSO CORPORATION
    Inventors: Hideo Tsukada, Kouichi Mochizuki
  • Publication number: 20240060996
    Abstract: The present invention relates to a method for assessing mitochondrial function in a tissue or organ other than the kidney in a test subject, including: a step of calculating a ratio (BUN/CRE) of blood urea nitrogen (BUN) concentration to blood creatinine (CRE) concentration in a test subject; and a step of estimating mitochondrial activity in a tissue or organ other than the kidney in the test subject using the calculated ratio (BUN/CRE).
    Type: Application
    Filed: December 17, 2021
    Publication date: February 22, 2024
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventors: Hiroyuki OHBA, Hideo TSUKADA
  • Publication number: 20230364273
    Abstract: The present invention relates to an agent for detecting an interaction between tissues and organs, the agent containing a compound represented by General Formula (1-0) as an active component. [In General Formula (1-0), R represents —O(CH2)n—, —O(CH2)nOC2H4—, —CH2O(CH2)n—, or —CH2O(CH2)nOC2H4—, n represents an integer of 1 to 5, and Q1 represents F or —OCH3].
    Type: Application
    Filed: October 28, 2021
    Publication date: November 16, 2023
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventors: Hiroyuki OHBA, Hideo TSUKADA
  • Publication number: 20230256120
    Abstract: The present invention relates to a method for diagnosing a pancreatic function, including: a step of administering a diagnostic agent for a pancreatic function which contains a compound represented by General Formula (1-0) as an active component to a subject; a step of detecting the compound (1-0) accumulated in the pancreas; and a step of quantitatively analyzing an amount of compound (1-0) accumulated in the pancreas. [In General Formula (1-0), R represents —O(CH2)n—, —O(CH2)nOC2H4—, —CH2O(CH2)n—, or —CH2O(CH2)nOC2H4—, n represents an integer of 1 to 5, and Q1 represents F or —OCH3].
    Type: Application
    Filed: July 13, 2021
    Publication date: August 17, 2023
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventors: Hiroyuki OHBA, Hideo TSUKADA
  • Publication number: 20230124555
    Abstract: A plurality of injection holes include at least one flat injection hole while an outlet opening of the at least one flat injection hole has a long axis and a short axis, and the at least one flat injection hole includes at least one specific flat injection hole. The specific flat injection hole has an injection hole axis that connects between a center of an inlet opening and a center of the outlet opening, and the long axis of the outlet opening is perpendicular to a plane which includes the injection hole axis and is parallel with the valve axis. An inner wall of the outlet opening has two planar portions which are opposed to each other while the long axis is interposed between the planar portions.
    Type: Application
    Filed: December 19, 2022
    Publication date: April 20, 2023
    Inventors: Hideo TSUKADA, Kiyotaka YOSHIMARU
  • Publication number: 20220401590
    Abstract: The present invention relates to a compound represented by the following General Formula (1) or a salt thereof. In General Formula (1), R1, R2, R3 and R4 each independently represent a hydrogen atom, a linear or branched alkyl group which may have a substituent or the like. R1 and R2 may be bonded to each other to form a ring. R3 and R4 may be bonded to each other to form a ring. R1 and/or R2 may be bonded to a 6-membered ring to which —NR1R2 is bonded to form a ring. R3 and/or R4 may be bonded to a 6-membered ring to which —NR3R4 is bonded to form a ring. R5 represents —11CH3, a linear or branched alkyl group which may have a substituent or the like. R6 represents —F, —18F or the like. X, Y and Z each independently represent a carbon atom, an oxygen atom or the like. n is 0 or 1.
    Type: Application
    Filed: November 4, 2020
    Publication date: December 22, 2022
    Applicants: SHIZUOKA PREFECTURAL UNIVERSITY CORPORATION, MEDICAL CORPORATION KINSHUKAI, HAMAMATSU PHOTONICS K.K.
    Inventors: Kenichiro TODOROKI, Yoshitaka HAMASHIMA, Hiromichi EGAMI, Satoshi NAKAGAWA, Toshihiro SAKAI, Osamu INOUE, Shingo NISHIYAMA, Masakatsu KANAZAWA, Hideo TSUKADA
  • Publication number: 20210340943
    Abstract: A movable core is driven by a magnetic attraction force with a fixed core to move a valve body to inject fuel. A yoke accommodates the fixed core. A coil is in a coil chamber between the fixed core and the yoke. The coil chamber is filled with a filling resin member being electrically insulative. The fixed core has a core facing surface facing the movable core and includes a protruding portion that protrudes radially outer side and is in contact with the yoke to conduct the magnetic flux. A resin molding flow channel is formed in the protruding portion to cause molten resin serving as the filling resin member to flow into the coil chamber. A length of the protruding portion along a cylinder center line is set to be shorter toward a radially outer side.
    Type: Application
    Filed: July 15, 2021
    Publication date: November 4, 2021
    Inventors: Hideo TSUKADA, Kouichi MOCHIZUKI
  • Patent number: 9914424
    Abstract: An inflator (3) includes an inflator main body (10) which is has a tubular shape and has a plurality of gas injection holes (11) on a circumferential surface, and a steel-made collar member (20) which has a gas jet reception part (28) that is disposed so as to face a gas injection holes formation area (R) of the inflator main body (10) across a space.
    Type: Grant
    Filed: August 2, 2016
    Date of Patent: March 13, 2018
    Assignees: HONDA MOTOR CO., LTD., TAKATA CORPORATION
    Inventors: Daiei Tonooka, Norihisa Okada, Hideo Tsukada, Akira Tsujie
  • Patent number: 9872928
    Abstract: The present invention provides a diagnostic agent for a therapeutic effect on cancer, containing a compound represented by formula (1-0). (In formula (1-0), R represents —O(CH2)n—, —O(CH2)nOC2H4—, —CH2O(CH2)n—, or —CH2O(CH2)nOC2H4—, n represents an integer of 1 to 5, and Q1 represents F or —OCH3.
    Type: Grant
    Filed: September 18, 2014
    Date of Patent: January 23, 2018
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Hideo Tsukada, Masakatsu Kanazawa, Norihiro Harada, Shingo Nishiyama
  • Patent number: 9610369
    Abstract: The present invention provides a compound represented by formula (I), wherein in formula (I), R1 represents CH3, F, (CH2)n—F, NH—(CH2)n—F, O—(CH2)n—F or S—(CH2)n—F, and n represents an integer of 1 to 3.
    Type: Grant
    Filed: April 2, 2014
    Date of Patent: April 4, 2017
    Assignees: HAMAMATSU PHOTONICS K.K., NARD INSTITUTE, LTD.
    Inventors: Hideo Tsukada, Shingo Nishiyama, Takeru Kitashoji, Tatsuhiro Kobashi, Yumi Nakamasu, Hidekazu Nakao
  • Patent number: 9598399
    Abstract: Provided is a compound represented by formula (1-0): wherein in formula (1-0), R represents —O(CH2)n—, —O(CH2)nOC2H4—, —CH2O(CH2)n— or —CH2O(CH2)nOC2H4—; n represents an integer from 1 to 5; and Q1 represents F or —OCH3.
    Type: Grant
    Filed: August 22, 2013
    Date of Patent: March 21, 2017
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Shingo Nishiyama, Norihiro Harada, Hideo Tsukada
  • Publication number: 20170036640
    Abstract: An inflator (3) includes an inflator main body (10) which is has a tubular shape and has a plurality of gas injection holes (11) on a circumferential surface, and a steel-made collar member (20) which has a gas jet reception part (28) that is disposed so as to face a gas injection holes formation area (R) of the inflator main body (10) across a space.
    Type: Application
    Filed: August 2, 2016
    Publication date: February 9, 2017
    Applicants: HONDA MOTOR CO., LTD., TAKATA CORPORATION
    Inventors: Daiei Tonooka, Norihisa Okada, Hideo Tsukada, Akira Tsujie
  • Publication number: 20160256578
    Abstract: The present invention provides a diagnostic agent for a therapeutic effect on cancer, containing a compound represented by formula (1-0). (In formula (1-0), R represents —O(CH2)n—, —O(CH2)nOC2H4—, —CH2O(CH2)n—, or —CH2O(CH2)nOC2H4—, n represents an integer of 1 to 5, and Q1 represents F or —OCH3.
    Type: Application
    Filed: September 18, 2014
    Publication date: September 8, 2016
    Applicant: Hamamatsu Photonics K.K.
    Inventors: Hideo TSUKADA, Masakatsu KANAZAWA, Norihiro HARADA, Shingo NISHIYAMA
  • Patent number: 9388122
    Abstract: It is intended to provide a radioactive tyrosine derivative represented by the formula (I) or a pharmaceutically acceptable salt thereof: wherein R1 represents a group selected from the group consisting of —11CH3, —11CH2CH3, —CH218F, and —CH2CH2CH218F.
    Type: Grant
    Filed: May 25, 2005
    Date of Patent: July 12, 2016
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Kengo Sato, Hideo Tsukada
  • Publication number: 20160051711
    Abstract: The present invention provides a compound represented by formula (I), wherein in formula (I), R1 represents CH3, F, (CH2)n—F, NH—(CH2)n—F, O—(CH2)n—F or S—(CH2)n—F, and n represents an integer of 1 to 3.
    Type: Application
    Filed: April 2, 2014
    Publication date: February 25, 2016
    Inventors: Hideo TSUKADA, Shingo NISHIYAMA, Takeru KITASHOJI, Tatsuhiro KOBASHI, Yumi NAKAMASU, Hidekazu NAKAO
  • Publication number: 20150225368
    Abstract: Provided is a compound represented by formula (1-0): wherein in formula (1-0), R represents —O(CH2)n—, —O(CH2)nOC2H4—, —CH2O(CH2)n— or —CH2O(CH2)nOC2H4—; n represents an integer from 1 to 5; and Q1 represents F or —OCH3.
    Type: Application
    Filed: August 22, 2013
    Publication date: August 13, 2015
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventors: Shingo Nishiyama, Norihiro Harada, Hideo Tsukada
  • Patent number: 8288604
    Abstract: A method of rapid methylation of an aromatic compound or an alkenyl compound, which is capable of obtaining an aromatic compound or an alkenyl compound labeled with a methyl group or a fluoromethyl group under a mild condition rapidly in high yield using an organic boron compound whose toxicity is not so high as a substrate. A kit for preparing a PET tracer and a method of producing a PET tracer can be practiced using the rapid methylation method. In an aprotic polar solvent, methyl iodide or X—CH2F (wherein X is a functional group which can be easily released as an anion), and an organic boron compound in which an aromatic ring or an alkenyl group is attached to boron are subjected to cross-coupling in the presence of a palladium(0) complex, a phosphine ligand, and a base.
    Type: Grant
    Filed: August 24, 2007
    Date of Patent: October 16, 2012
    Assignees: Gifu University, Riken, Hamamatsu Photonics K.K.
    Inventors: Masaaki Suzuki, Hisashi Doi, Hideo Tsukada
  • Publication number: 20110312914
    Abstract: The present invention provides a carbon monoxide removal agent that can be easily administered to a patient by injection or orally. The carbon monoxide removal agent of the present invention contains, as an active ingredient, an inclusion complex in which a cyclodextrin dimer represented by chemical formula (1) below includes a water-soluble metalloporphyrin. (In the formula, m represents either of number 1 or 2 and n represents any of number 1, 2, or 3.
    Type: Application
    Filed: August 25, 2011
    Publication date: December 22, 2011
    Applicants: TOKAI UNIVERSITY EDUCATIONAL SYSTEM, THE DOSHISHA
    Inventors: Koji KANO, Hiroaki KITAGISHI, Shigeru NEGI, Akiko KIRIYAMA, Akino HONBO, Akira KAWAGUCHI, Hideo TSUKADA
  • Publication number: 20110064662
    Abstract: Disclosed is a kit for use in the production of a molecular probe for PET drug screening for the purpose of producing a compound containing a short-lived radionuclide for PET applications. Specifically disclosed is a kit comprising a compound represented by the formula (I), (II) or (III) or a salt thereof. In the formulae, X1, X2, X3, X4, X5 and X6 are as defined in the description.
    Type: Application
    Filed: October 24, 2008
    Publication date: March 17, 2011
    Applicants: RIKEN, HAMAMATSU PHOTONICS K.K.
    Inventors: Hisashi Doi, Masaaki Suzuki, Hideo Tsukada
  • Publication number: 20100249477
    Abstract: It is intended to provide a method of rapid methylation of an aromatic compound or an alkenyl compound, which is capable of obtaining an aromatic compound or an alkenyl compound labeled with a methyl group or a fluoromethyl group under a mild condition rapidly in high yield using an organic boron compound whose toxicity is not so high as a substrate; a kit for preparing a PET tracer to be used in the same, and a method of producing a PET tracer using the same. In an aprotic polar solvent, methyl iodide or X—CH2F (wherein X is a functional group which can be easily released as an anion), an organic boron compound in which an aromatic ring or an alkenyl group is attached to boron are subjected to cross-coupling in the presence of a palladium(0) complex, a phosphine ligand, and a base.
    Type: Application
    Filed: August 24, 2007
    Publication date: September 30, 2010
    Applicants: GIFU UNIVERSITY, RIKEN, HAMAMATSU PHOTONICS K.K.
    Inventors: Masaaki Suzuki, Hisashi Doi, Hideo Tsukada