Abstract: A preparation includes an image sensor, a package, and a transparent plate. The image sensor has an imaging area on a front surface. The package is electrically connected to the image sensor. The transparent plate opposes the front surface of the image sensor with a mounting medium interposed therebetween. On the surface of the transparent plate, first and second grooves are formed. The image sensor is disposed between the first and second grooves.

Abstract: An image acquisition device according to the present disclosure includes a lighting system and an irradiation direction decision section. In a module, a subject and an imaging element are integrally formed. The lighting system sequentially irradiates the subject with illumination light in a plurality of different irradiation directions based on the subject such that the illumination light transmitted through the subject is incident on the imaging element. The module acquires a plurality of images according to the plurality of different irradiation directions. Before the plurality of images are acquired according to the plurality of different irradiation directions, the irradiation direction decision section decides the plurality of different irradiation directions based on a difference between a first preliminary image and a second preliminary image.

Abstract: An image generating system according to an aspect of the present disclosure includes an image obtaining device, an image generating circuit, and an image processing circuit. The image obtaining device includes an illuminating system that irradiates an object included in a module in which the object and an imaging element are integrated together, with light sequentially from a plurality of different radiation directions. The image obtaining device obtains a plurality of images corresponding to the plurality of different radiation directions. The image generating circuit generates a high-resolution image of the object having a higher resolution than each of the plurality of images by combining the plurality of images together. The image processing circuit detects noise resulting from a foreign object located farther from an imaging surface of the imaging element than the object and removes the noise.

Abstract: An imaging device includes a solid-state image element and an encapsulation section. The solid-state image element has an imaging region. In the imaging region, the solid-state image element receives light which is transmitted through an imaging target placed on the imaging region. The encapsulation section is placed on a surface, on which the imaging region is formed, so as to enclose the imaging target. The solid-state image element is peelable from the encapsulation section to enable the solid-state image element to be reused.

Abstract: An exemplary image forming apparatus includes: an illumination system which sequentially emits illuminating light beams from multiple different irradiation directions; an image sensor which captures a plurality of different images in the multiple different irradiation directions, respectively; an image processing section which forms a high-resolution image; and a memory which stores data about the ratio of light rays that have been incident on a photoelectric conversion section of each pixel of the image sensor to light rays that have passed through the upper surface of a plurality of subpixels included in the pixel with respect to each of the multiple irradiation directions. The image processing section forms the high-resolution image based on the data that has been retrieved from the memory by extracting, as a vector, a set of pixel values associated with the multiple irradiation directions from pixel values that form each of the plurality of images.

Abstract: An exemplary image forming apparatus according to the present disclosure includes: a light source which irradiates an object with light and of which the orientation and position are fixed; a tilting mechanism which tilts the object at multiple tilt angles; an image sensor which is arranged at a position where the light that has been transmitted through the object is incident, gets tilted along with the object by the tilting mechanism, and captures a plurality of images at the multiple tilt angles; and an image processing section which forms a high-resolution image of the object, having a higher resolution than any of the plurality of images, by synthesizing the plurality of images together.

Abstract: A pathological diagnosis support apparatus outputs a diagnostic region that is to be used as a target for diagnosis in a specimen image representing a specimen that is a target for pathological diagnosis, and includes: a target obtainment unit which obtains the specimen image and specimen information related to a scheme for preparing the specimen; a criterion obtainment unit which obtains a criterion corresponding to the specimen information from a database associating, for each of a plurality of specimens, specimen information related to a scheme for preparing each of the plurality of specimens with a criterion indicating a condition of a positive rate which is to be satisfied by the diagnostic region in a specimen image; and an output unit which outputs, as the diagnostic region, each of one or more regions in the specimen image having the positive rate determined to satisfy a condition indicated by the criterion obtained by the criterion obtainment unit.

Abstract: An image measurement apparatus includes: an image acquiring unit that acquires a sample image that is an image obtained by capturing an image of a sample; a standard color space converting unit that converts the sample image into a standard sample image that is an image in a standard color space; a color distribution normalizing unit that converts the standard sample image into a normalized sample image by converting pixel values of pixels in the standard sample image to cause a color distribution vector indicating a color distribution of the standard sample image to match a predetermined standard color distribution vector indicating a standard color distribution; and a positive rate acquiring unit that detects positive pixels by performing threshold processing on pixel values of pixels in the normalized sample image, and acquires a positive rate indicating a proportion of the detected positive pixels.

Abstract: An image processing apparatus for estimating a position in an image which an operator who observes the image is likely to observe as the candidate of a next position is provided. The image processing apparatus includes a next observation estimating unit that estimates a position selected from among a plurality of positions using a parameter indicating an operation history and information regarding an estimation result at least at a current time on the basis of a probability value obtained from a predetermined probability distribution and a displayed image generating unit that generates an image to be displayed so that at least the candidate of the next position is visually recognizable.

Abstract: An image processing apparatus including: an examination image obtaining unit obtaining an examination image of an examination subject; a shift-invariant feature quantity calculating unit calculating, for each pixel, a shift-invariant feature quantity represented by predetermined base vectors, from the examination image obtained by the examination image obtaining unit; a selecting unit selecting, on the examination image, a pixel having a matching degree lower than or equal to a predetermined threshold, between (i) a relative positional relationship of classes in normal images each of which does not include a lesion site and (ii) a relative positional relationship of the classes to which shift-invariant feature quantities respectively belong in the examination image, the classes being obtained by clustering the shift-invariant feature quantities: calculated from pixels included in the normal images; and represented by the predetermined base vectors; and an output unit outputting a result of the selection perfo

Abstract: A diagnostic support apparatus includes a base vector matching unit configured to match test image base vectors used for a base representation of a test image feature quantity of a test image and normal image base vectors used for a base representation of a normal image feature quantity of a normal image, a lesion determination unit configured to determine that the test image includes an image of a lesion site when a difference between a test image base coefficient and a normal image base coefficient is greater than a threshold, the test image base coefficient being a coefficient with which the test feature quantity is transformed to the base representation, and the normal image base coefficient being a coefficient with which the normal feature quantity is transformed to the base representation, and a determination result output unit configured to output a result of the determination by the lesion determination unit.

Abstract: The diagnostic support apparatus includes a feature quantity calculation unit vectorizing a test image into shift-invariant feature quantities, a base representation unit transforming the shift-invariant feature quantities of the test image into a linear combination of base vectors with first coefficients, the base vectors being calculated from a plurality of vectors representing shift-invariant feature quantities of a plurality of normal structural images including no lesion site, a lesion determination unit determining that the test image includes a lesion site when a difference between the first coefficients and second coefficients is greater than a determination threshold value, the second coefficients being used to transform shift-invariant feature quantities calculated from one of the normal structural images into a linear combination of the base vectors, and an output unit outputting a result of the determination by the lesion determination unit.

Abstract: An image processing apparatus includes a divider that generates a plurality pieces of third image information on the basis of a plurality of pieces of first image information and a plurality of pieces of second image information, a determiner that determines, on the basis of information regarding a sample, a filter to be used for the plurality of pieces of third image information, and a processor that deconvolutes each of the plurality of pieces of third image information using the determined filter. An image sensor that has received first resulting light emitted from a sample that has received first light emitted from a first angle outputs the plurality of pieces of first image information. The image sensor that has received second resulting light emitted from the sample that has received second light emitted from a second angle outputs the plurality of pieces of second image information.

Abstract: A preparation element set including an image sensor including a sensor surface, a sensor back surface, and a board; a package including a front surface, a back surface, and terminals on the back surface, the front surface touching or facing the sensor back surface; and a transparent plate facing the sensor surface with a subject placed therebetween, wherein the board includes a board surface and a board back surface, a distance between the board surface and the sensor surface is less than a distance between the board back surface and the sensor surface, a distance between the board surface and the sensor back surface is more than a distance between the board back surface and the sensor back surface, conductive holes pierce the board from the board surface to the board back surface, and conductors on the board surface are electrically connected to terminals by using the conductive holes.

Abstract: An image forming apparatus includes an imager that is electrically connected to an image sensor disposed at a position where light that has passed through a sample slice is incident on the image sensor, and an illumination system that emits illumination light successively in different illumination directions relative to a sample slice to illuminate the sample slice with the illumination light and that emits a first light having a peak in a first wavelength range and a second light having a peak in a second wavelength range. The image forming apparatus obtains a plurality of first-color images with the image sensor while the sample slice is being illuminated with the first light serving as the illumination light successively in the different illumination directions. The image forming apparatus obtains at least one second-color image with the image sensor while the sample slice is being illuminated with the second light in at least one of the different illumination directions.

Abstract: An image measurement device including: light sources that irradiate light beams having different peak wavelengths; a staining method obtaining unit which obtains information indicating a staining method of an inspection specimen; an image obtaining unit which: selects a combination of light sources according to the staining method, based on illumination information; and capture inspection images of the inspection specimen with light beams from the selected light sources, and capture reference images of a reference specimen with light beams from the respective light sources; a calculating unit which calculates a positivity based on the inspection images; and an evaluation unit which associates the staining method of the reference specimen with the combination of light sources to generate the illumination information based on a total value of coefficients in a linear sum of the ortho-normalization base vectors of a spectral distribution of light sources calculated based on the reference images.

Abstract: A medical image compression device includes: a compression target obtaining unit obtaining a target medical image to be compressed and diagnostic finding information for the target image; a clinical condition range obtaining unit dividing the target image into regions for the respective clinical conditions based on the diagnostic finding information; a pixel value prediction unit, for an arbitrary pixel, referring to a prediction knowledge database, and calculating a prediction probability of a value of a prediction target pixel based on the clinical condition of the prediction target pixel and the appearance distribution of the value of the prediction target pixel; a coding unit coding the value of the prediction target pixel based on the prediction probability of the pixel value; and an output unit outputting a code of the prediction target pixel after being coded by the coding unit.

Abstract: An exemplary image forming apparatus according to the present disclosure includes: a light source which irradiates an object with light and of which the orientation and position are fixed; a tilting mechanism which tilts the object at multiple tilt angles; an image sensor which is arranged at a position where the light that has been transmitted through the object is incident, gets tilted along with the object by the tilting mechanism, and captures a plurality of images at the multiple tilt angles; and an image processing section which forms a high-resolution image of the object, having a higher resolution than any of the plurality of images, by synthesizing the plurality of images together.

Abstract: An exemplary image forming apparatus includes: an illumination system which sequentially emits illuminating light beams from multiple different irradiation directions; an image sensor which captures a plurality of different images in the multiple different irradiation directions, respectively; an image processing section which forms a high-resolution image; and a memory which stores data about the ratio of light rays that have been incident on a photoelectric conversion section of each pixel of the image sensor to light rays that have passed through the upper surface of a plurality of subpixels included in the pixel with respect to each of the multiple irradiation directions. The image processing section forms the high-resolution image based on the data that has been retrieved from the memory by extracting, as a vector, a set of pixel values associated with the multiple irradiation directions from pixel values that form each of the plurality of images.

Abstract: A pathological diagnosis support apparatus which outputs a diagnostic region that is to be used as a target for diagnosis in a specimen image representing a specimen that is a target for pathological diagnosis, and includes: a target obtainment unit which obtains the specimen image and specimen information related to a scheme for preparing the specimen; a criterion obtainment unit which obtains a criterion corresponding to the specimen information from a database associating, for each of specimens, specimen information related to a scheme for preparing the specimen with a criterion indicating a condition of a positive rate which is to be satisfied by the diagnostic region in a specimen image; and an output unit which outputs, as the diagnostic region, each of one or more regions in the specimen image having the positive rate determined to satisfy a condition indicated by the criterion obtained by the criterion obtainment unit.