Patents by Inventor Hidetsugu SOTOYA

Hidetsugu SOTOYA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation method for high-purity 4?-galactosyl-lactose composition
    Patent number: 10221204
    Abstract: A composition which has high 4?-GL purity and can be used as a reference standard for various analyses can be obtained by a more convenient method than one conventionally used. A method for preparing a high-purity 4?-GL composition includes the steps of: (A) subjecting a 4?-GL-containing galacto-oligosaccharide to activated carbon column chromatography, and performing stepwise elution with plural organic solvent aqueous solutions, wherein the organic solvent aqueous solutions are used such that the concentration of the organic solvent in the organic solvent aqueous solution is higher than the concentration of the organic solvent in the immediately preceding organic solvent aqueous solution with respect to a series of elutions; and (B) adding an organic solvent to the final fraction eluted in step (A), and crystallizing the 4?-GL.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: March 5, 2019
    Assignee: Kabushiki Kaisha Yakult Honsha
    Inventors: Tetsuya Yamada, Hiroshi Hatano, Kazumasa Kimura, Hidetsugu Sotoya, Yoko Mori
  • PREPARATION METHOD FOR HIGH-PURITY 4'-GALACTOSYL-LACTOSE COMPOSITION
    Publication number: 20170044200
    Abstract: A composition which has high 4?-GL purity and can be used as a reference standard for various analyses can be obtained by a more convenient method than one conventionally used. A method for preparing a high-purity 4?-GL composition includes the steps of: (A) subjecting a 4?-GL-containing galacto-oligosaccharide to activated carbon column chromatography, and performing stepwise elution with plural organic solvent aqueous solutions, wherein the organic solvent aqueous solutions are used such that the concentration of the organic solvent in the organic solvent aqueous solution is higher than the concentration of the organic solvent in the immediately preceding organic solvent aqueous solution with respect to a series of elutions; and (B) adding an organic solvent to the final fraction eluted in step (A), and crystallizing the 4?-GL.
    Type: Application
    Filed: April 27, 2015
    Publication date: February 16, 2017
    Applicant: KABUSHIKI KAISHA YAKULT HONSHA
    Inventors: Tetsuya YAMADA, Hiroshi HATANO, Kazumasa KIMURA, Hidetsugu SOTOYA, Yoko MORI