Patents by Inventor Hilmar Bischoff

Hilmar Bischoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 7H-dibenzo[b,g][1,5]dioxocin-5-one derivatives and use thereof
    Publication number: 20060247303
    Abstract: The present invention relates to substituted 7H-dibenzo[b,g][1,5]dioxocin-5-one-derivatives, to processes for their preparation and to their use in medicaments, in particular as inhibitors of the cholesterol ester transfer protein (CETP) for the treatment and/or prevention of cardiovascular disorders, in particular hypolipoproteinaemia, dyslipidaemias, hypertriglyceridaemias, hyperlipidaemias and arteriosclerosis.
    Type: Application
    Filed: October 21, 2003
    Publication date: November 2, 2006
    Applicant: BAYER HEALTHCARE AG
    Inventors: Hilmar Bischoff, Frank-Thorsten Hafner, Carsten Schmeck, Joachim Telser, Alexandros Vakalopoulos, Gabriele Wirtz, Marcus Bauser, David Bruckner, Martina Wuttke
  • Heterocycles 3
    Patent number: 7115602
    Abstract: The invention relates to 7-(4-tert butyl-cyclohexyl)-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases.
    Type: Grant
    Filed: May 30, 2002
    Date of Patent: October 3, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Cristina Alonso-Alija, Heike Gielen, Martin Hendrix, Maria Niewöhner, Dagmar Schauss, Hilmar Bischoff, Nils Burkhardt, Volker Geiss, Karl-Heinz Schlemmer, Nigel J. Cuthbert, Mary F. Fitzgerald, Graham Sturton, Ulrich Niewöhner
  • Novel combination for treating sexual dysfunction
    Publication number: 20060189624
    Abstract: Disclosed is a combination preparation for the treatment of sexual dysfunction in men or women containing at least one active ingredient A and one active ingredient B as pharmaceutically active ingredients, whereby the active ingredient A is a PDE inhibitor, preferably a cGMP PDE inhibitor and the active ingredient B a lipid-reducing agent. Both the active ingredients A and B can be administered simultaneously or at alternate intervals, that is, as a functional unit or separated from each other.
    Type: Application
    Filed: February 3, 2006
    Publication date: August 24, 2006
    Applicant: Bayer Aktiengesellschaft
    Inventors: Erwin Bischoff, Hilmar Bischoff, Francois Giuliano
  • 5-Ethyl-imidazotriazinones
    Patent number: 7087605
    Abstract: The invention relates to novel 5-Ethyl-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases.
    Type: Grant
    Filed: May 21, 2002
    Date of Patent: August 8, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Cristina Alonso-Alija, Heike Gielen, Martin Hendrix, Maria Theresia Niewohner, legal representative, Dagmar Schauss, Hilmar Bischoff, Nils Burkhardt, Volker Geiss, Karl-Heinz Schlemmer, Nigel J. Cuthbert, Mary F. Fitzgerald, Richard Graham Sturton, Martin Michels, Ulrich Niewohner, deceased
  • Use of microsomal triglyceride transfer protein (MTP) inhibitors for reducing the number of postprandial triglyceride-rich lipoprotein particles (PPTRL)
    Publication number: 20060166999
    Abstract: The invention relates to the use of inhibitors of the microsomal triglyceride transfer protein (MTP) for reducing the number of postprandial triglyceride-rich lipoprotein particles (ppTRL) or for reducing their decomposition products i.e. the cholesterol-rich ‘small remnant particle’ (remnants). Said particles are associated with apolipoprotein B-48 (ApoB-48) and are designated as ‘ppTRL’ in the further course of events.
    Type: Application
    Filed: March 24, 2006
    Publication date: July 27, 2006
    Applicant: Bayer Aktiengesellschaft
    Inventors: Rudi Grutzmann, Ulrich Muller, Hilmar Bischoff, Siegfried Zaiss
  • 5-ethylimidarotriazones
    Patent number: 7074790
    Abstract: The invention relates to novel 5-ethyl-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases.
    Type: Grant
    Filed: May 5, 2003
    Date of Patent: July 11, 2006
    Inventors: Cristina Alonso-Alija, Heike Gielen-Haertwig, Martin Michels, Dagmar Karthaus, Hilmar Bischoff, Nils Burkhardt, Volker Geiss, Karl-Heinz Schlemmer, Nigel Cuthbert, Mary F. Fitzgerald, Graham Sturton, Maria Theresia Niewöhner, legal representative, Ulrich Niewöhner, deceased
  • Indolin phenylsulfonamide derivatives
    Publication number: 20060100230
    Abstract: The invention relates to novel substituted indolin phenylsulfonamide derivatives, to a method for the production thereof and to the use thereof in medicaments, especially as potent PPAR-delta activating compounds for the prophylaxis and/or treatment of cardiovascular diseases, especially dyslipidaemia and coronary heart diseases.
    Type: Application
    Filed: June 30, 2003
    Publication date: May 11, 2006
    Inventors: Hilmar Bischoff, Elke Dittrich-Wengenroth, Martina Wuttke, Heike Heckroth, Wolfgang Thielemann, Michael Woltering, Michael Otteneder
  • 4-heteroaryl-tetrahydroquinolines and their use as inhibitors of the cholesterin-ester transfer protein
    Publication number: 20060069112
    Abstract: Hetero-tetrahydroquinolines can be prepared either by condensing correspondingly substituted hetero-tetrahydroquinoline aldehydes with the desired substituent or by reducing the corresponding keto-substituted hetero-tetrahydroquinolines, followed by introduction of the desired substituent by customary methods. The hetero-tetrahydroquinolines are suitable for use as active compounds in medicaments, in particular in medicaments for treating artheriosclerosis and dyslipidaemias.
    Type: Application
    Filed: October 25, 2005
    Publication date: March 30, 2006
    Applicant: Bayer Aktiengesellschaft
    Inventors: Jürgen Stoltefuß, Michael Lörges, Gunter Schmidt, Arndt Brandes, Carsten Schmeck, Klaus-Dieter Bremm, Hilmar Bischoff, Delf Schmidt
  • Benzofuran derivatives
    Patent number: 7015246
    Abstract: The invention relates to novel benzofuran derivatives, to processes for preparing them and to their uses in medicaments.
    Type: Grant
    Filed: October 10, 2002
    Date of Patent: March 21, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Carsten Schmeck, Ulrich Müller, Gunter Schmidt, Josef Pernerstorfer, Hilmar Bischoff, Axel Kretschmer, Verena Vöhringer, Christiane Faeste, Helmut Haning, Markus Hauswald, Delf Schmidt, Martin Zoche, Heiner Apeler, Willi Jonghaus, Peter Reinemer
  • 5-ethylimidarotriazones
    Publication number: 20060040942
    Abstract: The invention relates to novel 5-ethyl-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases.
    Type: Application
    Filed: May 5, 2003
    Publication date: February 23, 2006
    Applicant: Bayer Healthcare AG
    Inventors: Cristina Alonso-Alija, Heike Gielen-Haertwig, Martin Michels, Dagmar Karthaus, Hilmar Bischoff, Nils Burkhardt, Volker Geiss, Karl-Heinz Schlemmer, Nigel Cuthbert, Mary Fitzgerald, Graham Sturton, Ulrich Niewohner, Maria Niewohner
  • 7-Aminoimidazotriazones
    Publication number: 20060040941
    Abstract: The invention relates to novel 7-amino-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases.
    Type: Application
    Filed: April 22, 2003
    Publication date: February 23, 2006
    Applicant: Bayer HealthCare AG
    Inventors: Cristina Alonso-Alija, Heike Gielen-Haertwig, Martin Michels, Dagmar Karthaus, Hilmar Bischoff, Nils Burkhardt, Volker Geiss, Karl-Heinz Schlemmer, Nigel Cuthbert, Mary Fitzgerald, Graham Sturton, Ulrich Niewohner, Maria Niewohner
  • 5-ethyl-imidazo (5,1-F) (1,2,4,) triazin-4 (3h)-ones as phosphodiesterase inhibitors
    Publication number: 20050272732
    Abstract: The invention relates to novel 5-ethyl-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases.
    Type: Application
    Filed: April 22, 2003
    Publication date: December 8, 2005
    Applicant: Bayer Healthcare AG
    Inventors: Cristina Alonso-Alija, Heike Gielen-Haertwig, Martin Michels, Dagmar Karthaus, Hilmar Bischoff, Nils Burkhardt, Volker Geiss, Karl-Heinz Schlemmer, Nigel Cuthbert, Mary Fitzgerald, Graham Sturton, Ulrich Niewohner, Maria Niewohner
  • 4-heteroaryl-tetrahydroquinolines and their use as inhibitors of the cholesterin-ester transfer protein
    Patent number: 6958346
    Abstract: Hetero-tetrahydroquinolines can be prepared either by condensing correspondingly substituted hetero-tetrahydroquinoline aldehydes with the desired substituent or by reducing the corresponding keto-substituted hetero-tetrahydroquinolines, followed by introduction of the desired substituent by customary methods. The hetero-tetrahydroquinolines are suitable for use as active compounds in medicaments, in particular in medicaments for treating artheriosclerosis and dyslipidaemias.
    Type: Grant
    Filed: October 31, 2001
    Date of Patent: October 25, 2005
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jürgen Stoltefuss, Michael Lögers, Gunter Schmidt, Arndt Brandes, Carsten Schmeck, Klaus-Dieter Bremm, Hilmar Bischoff, Delf Schmidt
  • Tetrahydroisoquinoline derivatives
    Publication number: 20050234096
    Abstract: The invention relates to novel substituted tetrahydroisoquinoline derivatives, methods for the production thereof and the use thereof in medicaments, especially as potent PPAR-delta activating compounds for the prophylaxis and/or treatment of cardiovascular diseases, especially dislipidaemia, coronary heart disease and arteriosclerosis.
    Type: Application
    Filed: May 5, 2003
    Publication date: October 20, 2005
    Inventors: Hilmar Bischoff, Elke Dittrich-Wengenroth, Verena Vohringer, Heike Heckroth, Andrea Vaupel, Michael Woltering, Michael Otteneder
  • Acetic acid derivatives
    Publication number: 20050154061
    Abstract: The present invention relates to novel substituted acetic acid derivatives, to processes for their preparation and to their use in medicaments, in particular as potent PPAR-delta-activating compounds for the prophylaxis and/or treatment of cardiovascular disorders, in particular dyslipidaemias and coronary heart diseases.
    Type: Application
    Filed: October 9, 2002
    Publication date: July 14, 2005
    Applicant: Bayer Aktiengesellschaft
    Inventors: Hilmar Bischoff, Elke Dittrich-Wengenroth, Heike Heckroth, Andrea Vaupel, Michael Woltering, Stefan Weigand
  • 4-Phenyltetrahydrochinoline utilized as an inhibitor of the cholesterol ester transfer protein
    Patent number: 6897317
    Abstract: The tetrahydroquinolines can be prepared by condensing appropriately substituted tetrahydroquinoline aldehydes with suitable substances and subsequently varying the substituents present by customary methods. The tetrahydroquinolines are suitable as active compounds in medicaments, in particular in medicaments for the treatment of arteriosclerosis and dyslipidaemias.
    Type: Grant
    Filed: March 31, 2003
    Date of Patent: May 24, 2005
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gunter Schmidt, Jürgen Stoltefuss, Michael Lögers, Arndt Brandes, Carsten Schmeck, Klaus-Dieter Bremm, Hilmar Bischoff, Delf Schmidt
  • Novel heterocycles 3
    Publication number: 20050065153
    Abstract: The invention relates to 7-(4-tert butyl-cyclohexyl)-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases.
    Type: Application
    Filed: October 12, 2004
    Publication date: March 24, 2005
    Applicant: Bayer Aktiengesellschaft
    Inventors: Cristina Alonso-Alija, Heike Gielen, Martin Hendrix, Ulrich Niewohner, Dagmar Schauss, Hilmar Bischoff, Nils Burkhardt, Volker Geiss, Karl-Heinz Schlemmer, Nigel Cuthbert, Mary Fitzgerald, Graham Sturton, Maria Niewohner
  • 3-'Hydroxy-(-4-trifluoromethylphenyl)-methyl-7-spirocyclobutyl-5,6,7 8-tetrahydroquinolin-5-ol derivatives and the use of the same as cholesterol ester transfer protein (cetp) inhibitors
    Publication number: 20050043341
    Abstract: The application relates to substituted tetrahydroquinoline derivatives, processes for their preparation and their use in medicaments.
    Type: Application
    Filed: September 18, 2002
    Publication date: February 24, 2005
    Inventors: Heike Gielen, Siegfried Goldmann, Jorg Keldenich, Holger Paulsen, Carsten Schmeck, Stephan Siegel, Hilmar Bischoff, Martin Raabe, Delf Schmidt, Christiane Faeste
  • Cycloalkano-indole and -azaindole derivatives
    Patent number: 6858622
    Abstract: Cycloalkano-indole and -azaindole derivatives are prepared by reaction of appropriately substituted carboxylic acids with amines. The cycloalkano-indole and -azaindole derivatives are suitable as active compounds for medicaments, preferably antiatherosclerotic medicaments.
    Type: Grant
    Filed: July 18, 2002
    Date of Patent: February 22, 2005
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ulrich Müller, Richard Connell, Siegfried Goldmann, Rudi Grützmann, Martin Beuck, Hilmar Bischoff, Dirk Denzer, Anke Domdey-Bette, Stefan Wohlfeil
  • Indole derivatives
    Publication number: 20050032874
    Abstract: The invention relates to new indole derivatives, processes for their preparation, and their use in medicaments.
    Type: Application
    Filed: December 23, 2003
    Publication date: February 10, 2005
    Applicant: Bayer Aktiengesellschaft
    Inventors: Helmut Haning, Michael Woltering, Gunter Schmidt, Hilmar Bischoff, Axel Kretschmer, Verena Vohringer, Christiane Faeste