Patents by Inventor Himanshu Jayant Sant
Himanshu Jayant Sant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230333103Abstract: Detecting a pathogen may include introducing a nonmagnetic metal into the sample where the nonmagnetic metal includes an antibody that is specific to the pathogen to form a complex of the nonmagnetic metal and the pathogen, removing the nonmagnetic metal that is not complexed with the pathogen from the sample, and detecting the presence of the nonmagnetic metal in the sample where the presence of the nonmagnetic metal indicates the presence of the pathogen.Type: ApplicationFiled: June 20, 2023Publication date: October 19, 2023Inventors: Ugochukwu Chinedu Nze, Himanshu Jayant Sant, Bruce Kent Gale, Michael Beeman, Christopher J. Lambert
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Publication number: 20230000772Abstract: An opioid independent surgical anesthetic composition includes an injectable dosage form of a hydrogel having a plurality of solid lipid matrix particles entrapped therein. The solid lipid matrix particles include a lipophilic local anesthetic drug and a lipid glyceride (e.g., saturated triglyceride or lipid blend of various lipid glycerides). Methods for creating a long-acting local anesthetic product can include creating a bulk solid of a lipid matrix product by heating a lipid solvent above its melting point, dissolving a lipophilic local anesthetic drug therein, reducing a temperature of the resultant drug-lipid solution to below the melting point of the lipid solvent, and heat annealing the lipid matrix to remove or reduce presence of any unstable polymorphs in the lipid matrix. The methods can further include crushing the bulk solid of the lipid matrix product to form solid lipid matrix particles and entrapping the solid lipid matrix particles within a hydrogel.Type: ApplicationFiled: March 1, 2022Publication date: January 5, 2023Inventors: Brett Davis, Andrew M. Simpson, Jayant P. Agarwal, Jill E. Shea, Himanshu Jayant Sant, Bruce K. Gale
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Patent number: 10842494Abstract: A nerve repair conduit configured to be secured on first and second portions of a selected nerve. The nerve repair conduit includes a polymeric body having a proximal end, a distal end, an exterior surface and an interior surface defining an interior lumen. In addition, the nerve conduit includes at least one drug reservoir to hold agent(s) that may facilitate nerve regeneration. The drugs diffuse from the drug reservoir(s) into the nerve repair conduit through an outlet (such as a hole or a semipermeable membrane) in proximity to the first and second portions of a selected nerve. The nerve repair conduit may be configured to deliver the agent(s) at a rate having substantially zero-order kinetics and/or at a constant rate over a selected period of time.Type: GrantFiled: August 3, 2018Date of Patent: November 24, 2020Assignee: University of Utah Research FoundationInventors: Jayant P. Agarwal, Bruce Kent Gale, Himanshu Jayant Sant, Pratima Labroo, Jill Shea
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Patent number: 10772633Abstract: A nerve repair conduit configured to be secured on first and second portions of a selected nerve. The nerve repair conduit includes a polymeric body having a proximal end, a distal end, an exterior surface and an interior surface defining an interior lumen. In addition, the nerve conduit includes at least one drug reservoir to hold agent(s) that may, for example, facilitate nerve regeneration. The drugs diffuse from the drug reservoir(s) into the nerve repair conduit through an outlet (e.g., a semipermeable membrane) in proximity to the first and second portions of a selected nerve. The nerve repair conduit may be configured to deliver the agent(s) at a rate having substantially zero-order kinetics and/or at a constant rate over a selected period of time (e.g., at least 1 week).Type: GrantFiled: April 2, 2018Date of Patent: September 15, 2020Assignee: University of Utah Research FoundationInventors: Jayant P. Agarwal, Bruce Kent Gale, Himanshu Jayant Sant, Keng-Min Lin
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Publication number: 20200278349Abstract: Detecting a pathogen may include introducing a nonmagnetic metal into the sample where the nonmagnetic metal includes an antibody that is specific to the pathogen to form a complex of the nonmagnetic metal and the pathogen, removing the nonmagnetic metal that is not complexed with the pathogen from the sample, and detecting the presence of the nonmagnetic metal in the sample where the presence of the nonmagnetic metal indicates the presence of the pathogen.Type: ApplicationFiled: February 28, 2020Publication date: September 3, 2020Inventors: Ugochukwu Chinedu Nze, Himanshu Jayant Sant, Bruce Kent Gale, Michael Beeman, Christopher J. Lambert
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Publication number: 20200271555Abstract: Sample preparation can include obtaining a sample in the form of a liquid mixture and forcing the liquid mixture through a cavitation chamber at an optimal pressure for separating pathogens from particles in the mixture without fragmenting at least 30% of the pathogens. Apparatuses used for sample preparation methods can include a fluid circuit, a cavitation chamber incorporated into the fluid circuit and having a channel with first, second, and third cross-sectional areas, the second cross-sectional area being downstream of and smaller than the first cross-sectional with respect to fluid flow through the fluid circuit and the third cross-sectional area being larger than and downstream of the second cross-sectional area with respect to fluid flow through the fluid circuit. The apparatus can include a pump in fluid communication with the cavitation chamber and a pressure sensor positioned upstream of the cavitation chamber.Type: ApplicationFiled: February 27, 2020Publication date: August 27, 2020Inventors: Ugochukwu Chinedu Nze, Himanshu Jayant Sant, Bruce Kent Gale, Christopher J. Lambert, Dhruv Patel, Michael Beeman
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Publication number: 20190038290Abstract: A nerve repair conduit configured to be secured on first and second portions of a selected nerve. The nerve repair conduit includes a polymeric body having a proximal end, a distal end, an exterior surface and an interior surface defining an interior lumen. In addition, the nerve conduit includes at least one drug reservoir to hold agent(s) that may facilitate nerve regeneration. The drugs diffuse from the drug reservoir(s) into the nerve repair conduit through an outlet (such as a hole or a semipermeable membrane) in proximity to the first and second portions of a selected nerve. The nerve repair conduit may be configured to deliver the agent(s) at a rate having substantially zero-order kinetics and/or at a constant rate over a selected period of time.Type: ApplicationFiled: August 3, 2018Publication date: February 7, 2019Inventors: Jayant P. Agarwal, Bruce Kent Gale, Himanshu Jayant Sant, Pratima Labroo, Jill Shea
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Publication number: 20190029686Abstract: A nerve repair conduit configured to be secured on first and second portions of a selected nerve. The nerve repair conduit includes a polymeric body having a proximal end, a distal end, an exterior surface and an interior surface defining an interior lumen. In addition, the nerve conduit includes at least one drug reservoir to hold agent(s) that may, for example, facilitate nerve regeneration. The drugs diffuse from the drug reservoir(s) into the nerve repair conduit through an outlet (e.g., a semipermeable membrane) in proximity to the first and second portions of a selected nerve. The nerve repair conduit may be configured to deliver the agent(s) at a rate having substantially zero-order kinetics and/or at a constant rate over a selected period of time (e.g., at least 1 week).Type: ApplicationFiled: April 2, 2018Publication date: January 31, 2019Inventors: Jayant P. Agarwal, Bruce Kent Gale, Himanshu Jayant Sant, Keng-Min Lin
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Patent number: 9931121Abstract: A nerve repair conduit configured to be secured on first and second portions of a selected nerve. The nerve repair conduit includes a polymeric body having a proximal end, a distal end, an exterior surface and an interior surface defining an interior lumen. In addition, the nerve conduit includes at least one drug reservoir to hold agent(s) that may, for example, facilitate nerve regeneration. The drugs diffuse from the drug reservoir(s) into the nerve repair conduit through an outlet (e.g., a semipermeable membrane) in proximity to the first and second portions of a selected nerve. The nerve repair conduit may be configured to deliver the agent(s) at a rate having substantially zero-order kinetics and/or at a constant rate over a selected period of time (e.g., at least 1 week).Type: GrantFiled: October 16, 2012Date of Patent: April 3, 2018Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATIONInventors: Jayant P. Agarwal, Bruce Kent Gale, Himanshu Jayant Sant, Keng-Min Lin
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Publication number: 20170059567Abstract: Methods of electrochemically detecting or quantifying an analyte by coupling a plurality of redox-active agents (e.g., guanine-rich oligonucleotides) to the analyte are disclosed. More particularly, this application discloses affinity-based methods for isolating one or more analytes from a sample and subsequently detecting or determining the concentration of the one or more analytes. Detecting or determining the concentration of one or more analytes may involve measuring the extent of oxidation of guanine nucleobases that have been or are coupled to the analyte.Type: ApplicationFiled: October 7, 2014Publication date: March 2, 2017Inventors: Himanshu Jayant Sant, Bruce K. Gale, Harikrishnan Jayamohan, Christopher J. Lambert, John Minson
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Publication number: 20140336681Abstract: A nerve repair conduit configured to be secured on first and second portions of a selected nerve. The nerve repair conduit includes a polymeric body having a proximal end, a distal end, an exterior surface and an interior surface defining an interior lumen. In addition, the nerve conduit includes at least one drug reservoir to hold agent(s) that may, for example, facilitate nerve regeneration. The drugs diffuse from the drug reservoir(s) into the nerve repair conduit through an outlet (e.g., a semipermeable membrane) in proximity to the first and second portions of a selected nerve. The nerve repair conduit may be configured to deliver the agent(s) at a rate having substantially zero-order kinetics and/or at a constant rate over a selected period of time (e.g., at least 1 week).Type: ApplicationFiled: October 16, 2012Publication date: November 13, 2014Inventors: Jayant P. Agarwal, Bruce Kent Gale, Himanshu Jayant Sant, Keng-Min Lin
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Publication number: 20090220923Abstract: An apparatus that includes an input having a surface area configured for altering its surface topology characteristic in accordance with a given function of an electronic device for providing a haptic operative input corresponding to said given function. There is a mechanism for altering surface topology of the surface area, and the mechanism does not comprise a piezoelectric motor.Type: ApplicationFiled: December 12, 2008Publication date: September 3, 2009Inventors: Ethan Smith, Himanshu Jayant Sant