Patents by Inventor Hirofumi Maeda
Hirofumi Maeda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240150793Abstract: A vector that includes a nucleic acid sequence encoding protelomerase, a pair of nucleic acid sequences recognized by the protelomerase, and a nucleic acid sequence located between the pair of nucleic acid sequences and encoding a protein.Type: ApplicationFiled: March 17, 2022Publication date: May 9, 2024Inventors: Teruyuki NISHI, Hirofumi MAEDA, Mitsuaki KITANO
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Patent number: 11962433Abstract: A switch device includes a plurality of communication ports; a switch unit configured to relay a frame, which has been transmitted from a function unit and to which information including an ID of a VLAN is added, to another function unit via a communication port; and a duplication unit configured to, when the diagnosis device is connected to another switch device, duplicate the frame to be relayed via a designated communication port among the plurality of communication ports, and generate a duplicate frame for diagnosis that is a frame obtained by adding, to a duplicate frame obtained through the duplication, specific information indicating that the duplicate frame for diagnosis should be transmitted to the diagnosis device. The switch unit outputs the duplicate frame for diagnosis generated by the duplication unit from a communication port corresponding to the other switch device.Type: GrantFiled: February 2, 2021Date of Patent: April 16, 2024Assignees: SUMITOMO ELECTRIC INDUSTRIES, LTD., SUMITOMO WIRING SYSTEMS, LTD., AUTONETWORKS TECHNOLOGIES, LTD., TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Akihito Iwata, Tatsuya Izumi, Hirofumi Urayama, Tadashi Matsumoto, Darmawan Go, Hideki Maeda, Takeshi Hagihara, Masashi Amesara, Hisashi Furukawa, Shu Ishizuka, Hideki Goto
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Publication number: 20230144068Abstract: A method for preparing a modified vector and a method for modifying a vector, the methods including: binding a functional group (A) in a linker compound to a functional group in a vector, wherein the functional group (A) is capable of binding to the functional group, the linker compound includes the functional group (A) and a functional group (B), and the functional group (B) is capable of binding to a ligand compound; and binding a functional group (C) in the ligand compound to the functional group (B), wherein the functional group (C) is capable of binding to the functional group (B) and the ligand compound includes the functional group (C).Type: ApplicationFiled: February 18, 2021Publication date: May 11, 2023Applicant: KANEKA CORPORATIONInventors: Hirofumi MAEDA, Takahide SASAKI, Mitsuaki KITANO
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Publication number: 20220162259Abstract: A peptide complex including: a peptide; and a cell-membrane-permeability-imparting group introduced into the peptide, wherein the cell-membrane-permeability-imparting group includes a dendritic structure including four or more branches, and at least four branches of the four or more branches include basic functional groups at ends thereof.Type: ApplicationFiled: February 14, 2020Publication date: May 26, 2022Applicant: KANEKA CORPORATIONInventors: Keishi TAKATSU, Toshihiro SHIKAKURA, Yuka MATSUDA, Tatsuya MOUTAI, Hirofumi MAEDA, Hiroshi KITA, Mitsuaki KITANO
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Patent number: 11248226Abstract: A method for producing a ribosome display complex includes obtaining a ribosome complex including an unmodified polypeptide chain, an mRNA molecule and a ribosome by initiating translation of the mRNA molecule in a cell-free peptide synthesis system including the ribosome, and modifying the unmodified polypeptide chain by reacting a side chain reactive functional group in the unmodified polypeptide chain with a modifying reagent to produce a ribosome display complex including a modified polypeptide chain, the mRNA molecule and the ribosome. The unmodified polypeptide chain includes at least one reactive amino acid residue selected from the group consisting of a cysteine residue, a lysine residue, a histidine residue and a tryptophan residue. The at least one reactive amino acid residue includes the side chain reactive functional group, and the mRNA molecule includes a base sequence encoding an amino acid sequence of the polypeptide chain.Type: GrantFiled: December 7, 2018Date of Patent: February 15, 2022Assignee: KANEKA CORPORATIONInventors: Hiroshi Kita, Toshihiro Shikakura, Hirofumi Maeda, Keishi Takatsu
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Patent number: 11248555Abstract: As a control method for internal combustion engine, a part of a low-medium revolution speed/low-medium load region of an internal combustion engine is set as a lean combustion region, homogeneous combustion is performed in an operating region within the lean combustion region where a load is relatively low, by injecting fuel at least once between an intake stroke and the first half of a compression stroke to form a homogeneous air-fuel mixture in a combustion chamber, and stratified combustion is performed in an operating region within the lean combustion region where the load is relatively high, by injecting the fuel at least once, respectively, between the intake stroke and the first half of the compression stroke as well as in the second half of the compression stroke to form a stratified air-fuel mixture in the combustion chamber.Type: GrantFiled: May 24, 2017Date of Patent: February 15, 2022Assignee: NISSAN MOTOR CO., LTD.Inventors: Hirofumi Maeda, Masaharu Kassai
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Patent number: 10890155Abstract: In a control method for internal combustion engine for forming a stratified air-fuel mixture in a combustion chamber and performing stratified combustion by injecting fuel at least once each time between an intake stroke and the first half of a compression stroke and in the second half of the compression stroke, spark ignition is started by flowing a relatively large discharge current into the ignition plug when flow energy around the ignition plug is increased by energy of a fuel spray injected in the second half of the compression stroke and, thereafter, the discharge current is made relatively smaller and discharged for a predetermined period.Type: GrantFiled: May 24, 2017Date of Patent: January 12, 2021Assignee: NISSAN MOTOR CO., LTD.Inventors: Hirofumi Maeda, Masaharu Kassai
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Publication number: 20200200116Abstract: As a control method for internal combustion engine, a part of a low-medium revolution speed/low-medium load region of an internal combustion engine is set as a lean combustion region, homogeneous combustion is performed in an operating region within the lean combustion region where a load is relatively low, by injecting fuel at least once between an intake stroke and the first half of a compression stroke to form a homogeneous air-fuel mixture in a combustion chamber, and stratified combustion is performed in an operating region within the lean combustion region where the load is relatively high, by injecting the fuel at least once, respectively, between the intake stroke and the first half of the compression stroke as well as in the second half of the compression stroke to form a stratified air-fuel mixture in the combustion chamber.Type: ApplicationFiled: May 24, 2017Publication date: June 25, 2020Applicant: NISSAN MOTOR CO., LTD.Inventors: Hirofumi MAEDA, Masaharu KASSAI
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Publication number: 20200173417Abstract: In a control method for internal combustion engine for forming a stratified air-fuel mixture in a combustion chamber and performing stratified combustion by injecting fuel at least once each time between an intake stroke and the first half of a compression stroke and in the second half of the compression stroke, spark ignition is started by flowing a relatively large discharge current into the ignition plug when flow energy around the ignition plug is increased by energy of a fuel spray injected in the second half of the compression stroke and, thereafter, the discharge current is made relatively smaller and discharged for a predetermined period.Type: ApplicationFiled: May 24, 2017Publication date: June 4, 2020Applicant: NISSAN MOTOR CO., LTD.Inventors: Hirofumi MAEDA, Masaharu KASSAI
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Publication number: 20190169600Abstract: A method for producing a ribosome display complex includes obtaining a ribosome complex including an unmodified polypeptide chain, an mRNA molecule and a ribosome by initiating translation of the mRNA molecule in a cell-free peptide synthesis system including the ribosome, and modifying the unmodified polypeptide chain by reacting a side chain reactive functional group in the unmodified polypeptide chain with a modifying reagent to produce a ribosome display complex including a modified polypeptide chain, the mRNA molecule and the ribosome. The unmodified polypeptide chain includes at least one reactive amino acid residue selected from the group consisting of a cysteine residue, a lysine residue, a histidine residue and a tryptophan residue. The at least one reactive amino acid residue includes the side chain reactive functional group, and the mRNA molecule includes a base sequence encoding an amino acid sequence of the polypeptide chain.Type: ApplicationFiled: December 7, 2018Publication date: June 6, 2019Applicant: KANEKA CORPORATIONInventors: Hiroshi Kita, Toshihiro Shikakura, Hirofumi Maeda, Keishi Takatsu
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Patent number: 9957033Abstract: A fence 30A is installed on an inner surface 21a of a door 20A on the side which faces a landing gear bay 15, the fence 30A rising inwardly of the airframe from the inner surface 21a. When the door 20A opens outwardly of an airframe due to a pressure difference between the side of an outer surface 21c of the door 20A and the side of an inner surface 21a facing inner part of the landing gear bay 15 during a flight of an aircraft 10, the fence 30A closes a gap between the door 20A and an opening 15a of the landing gear bay 15, and thereby prevents air from flowing into the landing gear bay 15 through the gap.Type: GrantFiled: January 14, 2013Date of Patent: May 1, 2018Assignee: MITSUBISHI AIRCRAFT CORPORATIONInventors: Ichiro Maeda, Hirofumi Maeda
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Patent number: 9951742Abstract: An ignition device for an internal combustion engine (1) includes a superpose voltage generation circuit (47) that, after the initiation of a discharge with the application of a discharge voltage by a secondary coil, applies a superpose voltage between electrodes of an ignition plug (29) in the same direction as the discharge voltage to continue a discharge current, and performs a superposed discharge in a superposed discharge activation range of high exhaust recirculation rate. Upon shift from the superposed discharge activation range of high exhaust recirculation rate to a superposed discharge deactivation range of low exhaust recirculation rate, the deactivation of the superposed discharge is delayed by a delay time ?T. Although the exhaust gas recirculation rate becomes temporarily increased with decrease in intake air after the closing of an exhaust gas recirculation control valve, the superposed discharge is continued for the delay time ?T so as to avoid misfiring.Type: GrantFiled: December 16, 2013Date of Patent: April 24, 2018Assignee: NISSAN MOTOR CO., LTD.Inventors: Taisuke Shiraishi, Tatsuya Yaguchi, Hirofumi Maeda
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Publication number: 20170226159Abstract: A method for producing a purified peptide from a supported crude peptide having a support and a first peptide chain bonded to the support at the C-terminus. The method includes: introducing a linker and a hydrophilic unit to an amino group of the first peptide chain of the supported crude peptide; cleaving a bond between the first peptide chain and the support before or after at least one of the linker and the hydrophilic unit is introduced to the amino group of the first peptide chain such that a support-free hydrophilized peptide is obtained; treating the support-free hydrophilized peptide by liquid chromatography; and cleaving a bond between the linker and the first peptide chain in the support-free hydrophilized peptide by chemical treatment after the liquid chromatography treatment such that a peptide including the first peptide chain is obtained.Type: ApplicationFiled: September 25, 2015Publication date: August 10, 2017Applicants: KANEKA CORPORATION, AnaSpec, Inc.Inventors: Keishi TAKATSU, Hirofumi MAEDA, Akio FUJII, Fengying LI, Xoapbing WANG
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Publication number: 20160341172Abstract: An ignition device for an internal combustion engine (1) includes a superpose voltage generation circuit (47) that, after the initiation of a discharge with the application of a discharge voltage by a secondary coil, applies a superpose voltage between electrodes of an ignition plug (29) in the same direction as the discharge voltage to continue a discharge current, and performs a superposed discharge in a superposed discharge activation range of high exhaust recirculation rate. Upon shift from the superposed discharge activation range of high exhaust recirculation rate to a superposed discharge deactivation range of low exhaust recirculation rate, the deactivation of the superposed discharge is delayed by a delay time ?T. Although the exhaust gas recirculation rate becomes temporarily increased with decrease in intake air after the closing of an exhaust gas recirculation control valve, the superposed discharge is continued for the delay time ?T so as to avoid misfiring.Type: ApplicationFiled: December 16, 2013Publication date: November 24, 2016Applicant: NISSAN MOTOR CO., LTD.Inventors: Taisuke Shiraishi, Tatsuya Yaguchi, Hirofumi Maeda
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Publication number: 20120264687Abstract: An object of the invention is to provide a pharmaceutical composition that contains erythropoietin as the active ingredient and has, when administered in humans and/or animals, a hematopoietic effect that lasts for not less than seven days. The invention provides a pharmaceutical composition containing, in an amount equal to not less than 50% of the total erythropoietin, erythropoietin to which two or more water-soluble long-chain molecules are added. The invention also provides a pharmaceutical composition containing erythropoietin to which a water-soluble long-chain molecule is added, wherein the water-soluble long-chain molecule has a molecular weight of not less than 30 kDa. The invention further provides a pharmaceutical composition containing erythropoietin to which a water-soluble long-chain molecule is added, wherein the water-soluble long-chain molecule has a branched chain.Type: ApplicationFiled: September 15, 2010Publication date: October 18, 2012Applicant: Kaneka CorporationInventors: Nobutaka Tani, Toshihide Fujii, Hiroyuki Watanabe, Hirofumi Maeda
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Patent number: 8264624Abstract: Provided is a digitizer function-equipped liquid crystal display device capable of preventing the wire shadows of a loop antenna from being projected on a liquid crystal panel and capable of being applied to a large size liquid crystal panel. It is also possible to provide an information processing electronic device and a game device provided with the digitizer function-equipped liquid crystal display device.Type: GrantFiled: May 19, 2008Date of Patent: September 11, 2012Assignee: Kabushiki Kaisha SegaInventors: Toshiyuki Kaji, Gou Hirose, Takayuki Ohnishi, Hirofumi Maeda
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Patent number: 8252919Abstract: The present invention relates to a method for producing a 2?-hydroxy-protected nucleoside derivative by reacting a ribonucleoside with an acylating or a carbamoylating reagent in the presence of a metal complex consisting of a copper compound and an optically active ligand. By the method according to the present invention, a 2?-hydroxy-protected ribonucleoside derivative, which is an important intermediate for producing an oligonucleoside, can be easily produced with good regioselectivity from a nucleoside derivative of which 2?,3?-hydroxy groups are not protected.Type: GrantFiled: February 26, 2009Date of Patent: August 28, 2012Assignee: Kaneka CorporationInventors: Hirofumi Maeda, Akio Fujii, Masaru Mitsuda
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Patent number: 8013193Abstract: Disclosed is a method for producing an alcohol from a lactone or a carboxylic acid ester, which enables to produce an alcohol from a lactone or a carboxylic acid ester under relatively mild conditions with high yield and high catalytic efficiency. This method also enables to produce an optically active alcohol from an optically active lactone or an optically active carboxylic acid ester. Specifically disclosed is a method for producing an alcohol by hydrogen reducing a lactone or a carboxylic acid ester in the presence of a catalyst containing ruthenium and a phosphine compound represented by the following general formula (1): wherein R1 represents a spacer; R2, R3, R4, R5, R6 and R7 independently represent a hydrogen atom, an alkyl group having 1-12 carbon atoms, an aryl group or a heterocyclic group; and R8, R9, R10, R11, R12 and R13 independently represent an alkyl group having 1-12 carbon atoms, an aryl group or a heterocyclic group.Type: GrantFiled: April 2, 2008Date of Patent: September 6, 2011Assignees: Kaneka Corporation, Takasago International CorporationInventors: Hirofumi Maeda, Kenji Inoue, Takaji Matsumoto, Izuru Nagasaki, Ryoji Noyori, Susumu Saito
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Publication number: 20110009609Abstract: The present invention relates to a method for producing a 2?-hydroxy-protected nucleoside derivative by reacting a ribonucleoside with an acylating reagent in the presence of a metal complex consisting of a copper compound and an optically active ligand. By the method according to the present invention, a 2?-hydroxy-protected ribonucleoside derivative, which is an important intermediate for producing an oligonucleoside, can be easily produced with good regioselectivity from a nucleoside derivative of which 2?,3?-hydroxy groups are not protected.Type: ApplicationFiled: February 26, 2009Publication date: January 13, 2011Inventors: Hirofumi Maeda, Akio Fujii, Masaru Mitsuda
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Publication number: 20100171891Abstract: Provided is a digitizer function-equipped liquid crystal display device capable of preventing the wire shadows of a loop antenna from being projected on a liquid crystal panel and capable of being applied to a large size liquid crystal panel. It is also possible to provide an information processing electronic device and a game device provided with the digitizer function-equipped liquid crystal display device.Type: ApplicationFiled: May 19, 2008Publication date: July 8, 2010Applicant: KABUSHIKI KAISHA SEGA DOING BUSINESS AS SEGA CORPInventors: Toshiyuki Kaji, Gou Hirose, Takayuki Ohnishi, Hirofumi Maeda