Patents by Inventor Hirohiko Tsuzuki

Hirohiko Tsuzuki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050146723
    Abstract: An object of the present invention is to suppress the noise width of a reference cell during measurement and the base line fluctuation. The present invention provides a method for measuring a change in surface plasmon resonance, which comprises: using a surface plasmon resonance measurement device comprising a flow channel system having a cell formed on a metal film and a light-detecting means for detecting the state of surface plasmon resonance by measuring the intensity of a light beam totally reflected on the meal film; and exchanging the liquid contained in the above flow channel system, wherein the above method is characterized in that a change in surface plasmon resonance is measured in a state where the flow of the liquid has been stopped, after the liquid contained in the above flow channel system has been exchanged.
    Type: Application
    Filed: December 1, 2004
    Publication date: July 7, 2005
    Inventors: Koji Kuruma, Hirohiko Tsuzuki
  • Publication number: 20050042745
    Abstract: An object of the present invention is to construct a culture device optimized for culturing animal cells. The present invention provides a device for culturing cells which comprises at least one water-containing polymer gel film for adhering animal cells onto at least one surface of the film, and has a structure capable of supplying different liquids to both sides of the film.
    Type: Application
    Filed: July 15, 2004
    Publication date: February 24, 2005
    Inventors: Hirohiko Tsuzuki, Satoru Toda, Yasunori Ichikawa, Tetsuo Kurahashi, Fumiko Shiraishi
  • Publication number: 20050004469
    Abstract: The ultrasonic scatterer of the invention comprises gas-containing particles having an average particle size of 0.01 ?m to 10 ?m, the ultrasonic imaging method of the invention comprises transmitting an ultrasonic wave continuing for ten cycles or more; transmitting an ultrasonic wave continuing for four cycles or more and less than ten cycles after a predetermined period passes, and the ultrasonic imaging apparatus of the invention comprises transmitting means for sending a driving signal to the ultrasonic probe so as to transmit, to a subject, an ultrasonic wave continuing for four cycles or more and less than ten cycles after a predetermined period passes subsequently to transmitting, to the subject, of an ultrasonic wave continuing for ten cycles or more.
    Type: Application
    Filed: July 16, 2004
    Publication date: January 6, 2005
    Inventor: Hirohiko Tsuzuki
  • Patent number: 6793626
    Abstract: The ultrasonic scatterer of the invention comprises gas-containing particles having an average particle size of 0.01 &mgr;m to 10 &mgr;m, the ultrasonic imaging method of the invention comprises transmitting an ultrasonic wave continuing for ten cycles or more; transmitting an ultrasonic wave continuing for four cycles or more and less than ten cycles after a predetermined period passes, and the ultrasonic imaging apparatus of the invention comprises transmitting means for sending a driving signal to the ultrasonic probe so as to transmit, to a subject, an ultrasonic wave continuing for four cycles or more and less than ten cycles after a predetermined period passes subsequently to transmitting, to the subject, of an ultrasonic wave continuing for ten cycles or more.
    Type: Grant
    Filed: January 17, 2002
    Date of Patent: September 21, 2004
    Assignee: Fuji Photo Film Co., Ltd.
    Inventor: Hirohiko Tsuzuki
  • Publication number: 20040157328
    Abstract: A carrier for cell culture comprising a water-containing polymer gel containing chitosan, wherein the water-containing polymer gel is coated with collagen and/or alginic acid, and a carrier for cell culture, which comprises a gel layer containing chitosan and an inorganic layer adjacently provided to the gel layer.
    Type: Application
    Filed: October 24, 2003
    Publication date: August 12, 2004
    Applicant: FUJI PHOTO FILM CO., LTD.
    Inventors: Hirohiko Tsuzuki, Satoru Toda, Makoto Kato
  • Publication number: 20040137619
    Abstract: A method for detaching a carrier for cell culture, such as a carrier comprising a calcium alginate layer and a cell adhesion gel layer and the like, from cultured cells formed on a surface of said carrier, which comprises the step of bringing the carrier for cell culture into contact with a compound represented by the following formula (I):
    Type: Application
    Filed: October 23, 2003
    Publication date: July 15, 2004
    Applicant: FUJI PHOTO FILM CO., LTD.
    Inventors: Hirohiko Tsuzuki, Kazuhiro Aikawa, Akiko Matsuura
  • Patent number: 6761691
    Abstract: An ultrasonic diagnostic apparatus by which an image having superior space resolution is obtained. The apparatus includes: first means for transmitting an ultrasonic wave, which is continued for at least two cycles, to an object to be inspected, and for detecting an echo signal which is produced by reflection of the transmitted ultrasonic wave from tissue of the object to be inspected to thereby obtain a detection signal; second means for delaying the detection signal by such a time duration corresponding to one cycle of the transmitted ultrasonic wave to thereby obtain a delayed detection signal; and third means for obtaining image information related to the tissue of the object to be inspected based upon a difference between the detection signal and the delayed detection signal.
    Type: Grant
    Filed: July 19, 2001
    Date of Patent: July 13, 2004
    Assignee: Fuji Photo Film Co., Ltd.
    Inventor: Hirohiko Tsuzuki
  • Publication number: 20040072338
    Abstract: A carrier for cell culture comprising a carrier having a cationic group and polypeptide-modified portions formed on a surface of the carrier in a sea-island structure, and a carrier for cell culture comprising a water-containing gel comprising alginic acid, wherein a surface of the carrier is coated with collagen, and wherein the collagen is bound to a surface of the water-containing gel by means of chitosan.
    Type: Application
    Filed: July 7, 2003
    Publication date: April 15, 2004
    Applicant: FUJI PHOTO FILM CO., LTD.
    Inventors: Hirohiko Tsuzuki, Kazuhiro Aikawa, Makoto Kato, Akiko Matsuura
  • Publication number: 20030228693
    Abstract: A carrier for cell culture comprising an alginic acid gel layer laminated with a gel layer containing a cell adhesion substance, wherein the gel layer containing a cell adhesion substance has a dry thickness of less than 0.3 &mgr;m. The carrier for cell culture enables reproducible and convenient cell layer lamination without inhibiting growth and proliferation of cells upon solubilization of the carrier for preparation of a cell sheet.
    Type: Application
    Filed: March 11, 2003
    Publication date: December 11, 2003
    Applicant: FUJI PHOTO FILM CO., LTD.
    Inventors: Hirohiko Tsuzuki, Akiko Matsuura
  • Publication number: 20030148402
    Abstract: A method for conducting a receptor-ligand association reaction includes the steps of forcibly feeding a reaction solution containing a ligand labeled with a labeling substance from one side of a biochemical analysis unit formed with a plurality of absorptive regions spaced apart from each other and containing receptors toward the other side thereof so as to cut through the absorptive regions of the biochemical analysis unit and forcibly feeding the reaction solution from the other side of the biochemical analysis unit toward the one side thereof via at least one check valve, thereby selectively associating the ligand contained in the reaction solution with the receptors contained in the absorptive regions. According to this method, it is possible to efficiently associate a ligand with receptors fixed in the absorptive regions of the biochemical analysis unit and produce biochemical analysis data having an excellent quantitative characteristic with good repeatability.
    Type: Application
    Filed: January 27, 2003
    Publication date: August 7, 2003
    Applicant: FUJI PHOTO FILM CO., LTD.
    Inventors: Yoshikazu Amano, Hirohiko Tsuzuki
  • Publication number: 20030007895
    Abstract: A biochemical analysis unit includes a substrate made of a material capable of attenuating radiation energy and light energy and formed with a plurality of holes spaced apart from each other, a plurality of absorptive layers being formed on inner surfaces of the holes. According to the thus constituted biochemical analysis unit, it is possible to prevent noise caused by the scattering of electron beams (&bgr; rays) released from a radioactive labeling substance from being generated in biochemical analysis data even in the case of forming spot-like regions selectively containing a radioactive labeling substance in the biochemical analysis unit, superposing the biochemical analysis unit and a stimulable phosphor layer, exposing the stimulable phosphor layer to the radioactive labeling substance, irradiating the stimulable phosphor layer with a stimulating ray to excite the stimulable phosphor, and photoelectrically detecting the stimulated emission released from the stimulable phosphor layer.
    Type: Application
    Filed: June 18, 2002
    Publication date: January 9, 2003
    Applicant: FUJI PHOTO FILM CO., LTD.
    Inventor: Hirohiko Tsuzuki
  • Publication number: 20030003601
    Abstract: A biochemical analysis unit is obtained, which comprises a base plate having spot-shaped regions and has identification information, specific binding substances having been fixed respectively to the spot-shaped regions. A labeled organism-originating substance having identification information is subjected to specific binding to the specific binding substances. A label signal corresponding to a position of the spot-shaped region having thus been labeled selectively is read out to form data for a biochemical analysis. The identification information of the biochemical analysis unit and the identification information of the organism-originating substance are acquired and fed into an analysis apparatus, such that the correspondence relationship between the two pieces of the identification information is clear.
    Type: Application
    Filed: July 1, 2002
    Publication date: January 2, 2003
    Applicant: FUJI PHOTO FILM CO., LTD.
    Inventors: Masato Some, Katsuaki Muraishi, Hitoshi Shimizu, Nobuhiko Ogura, Tohru Tsuchiya, Hirohiko Tsuzuki
  • Publication number: 20020197729
    Abstract: A biochemical analysis unit includes a plurality of absorptive regions two-dimensionally formed so as to be spaced apart from each other by weaving a plurality of light shielding strips made of a material capable of attenuating radiation energy and a plurality of absorptive strips made of an absorptive material so that the light shielding strip is present between neighboring absorptive regions.
    Type: Application
    Filed: June 11, 2002
    Publication date: December 26, 2002
    Applicant: FUJI PHOTO FILM CO., LTD.
    Inventor: Hirohiko Tsuzuki
  • Publication number: 20020129656
    Abstract: The ultrasonic scatterer of the invention comprises gas-containing particles having an average particle size of 0.01 &mgr;m 10 &mgr;m, the ultrasonic imaging method of the invention comprises transmitting an ultrasonic wave continuing for ten cycles or more; transmitting an ultrasonic wave continuing for four cycles or more and less than ten cycles after a predetermined period passes, and the ultrasonic imaging apparatus of the invention comprises transmitting means for sending a driving signal to the ultrasonic probe so as to transmit, to a subject, an ultrasonic wave continuing for four cycles or more and less than ten cycles after a predetermined period passes subsequently to transmitting, to the subject, of an ultrasonic wave continuing for ten cycles or more.
    Type: Application
    Filed: January 17, 2002
    Publication date: September 19, 2002
    Inventor: Hirohiko Tsuzuki
  • Publication number: 20020045821
    Abstract: An ultrasonic diagnostic apparatus bywhich an image having superior space resolution is obtained. The apparatus includes: first means for transmitting an ultrasonic wave, which is continued for at least two cycles, to an object to be inspected, and for detecting an echo signal which is produced by reflection of the transmitted ultrasonic wave from tissue of the object to be inspected to thereby obtain a detection signal; second means for delaying the detection signal by such a time duration corresponding to one cycle of the transmitted ultrasonic wave to thereby obtain a delayed detection signal; and third means for obtaining image information related to the tissue of the object to be inspected based upon a difference between the detection signal and the delayed detection signal.
    Type: Application
    Filed: July 19, 2001
    Publication date: April 18, 2002
    Inventor: Hirohiko Tsuzuki
  • Patent number: 6274301
    Abstract: A photothermographic recording element having improved image tone and improved tone stability during storage is provided wherein at least one of constituent layers comprises (a) polymeric microparticulates containing a dyestuff, (b) microcapsules containing a dyestuff, and/or (c) an organic or inorganic pigment.
    Type: Grant
    Filed: October 16, 1998
    Date of Patent: August 14, 2001
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Hisashi Okamura, Hirohiko Tsuzuki, Itsuo Fujiwara, Yoshiharu Yabuki
  • Patent number: 6093529
    Abstract: An imaging material is provided in the form of a photothermographic or thermographic image forming layer containing an organic silver salt on one surface of a support and further comprising a polyvalent metal ion and a phthalic acid compound on the image forming layer-bearing surface of the support. The imaging material has improved shelf stability before and after image formation and the ease of handling and produces high-quality blue black tone images.
    Type: Grant
    Filed: April 16, 1998
    Date of Patent: July 25, 2000
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Hirohiko Tsuzuki, Hisashi Okamura, Itsuo Fujiwara, Yoshiharu Yabuki, Masaki Noro
  • Patent number: 6068968
    Abstract: A photothermographic material containing photosensitive silver halide grains, in which a cyanine dye containing at least one of an alkylthio group, an arylthio group, and a substituent group having a thioether bond is included, thereby the photographic material exhibiting low fogging, high sensitivity, and improved stability.
    Type: Grant
    Filed: March 3, 1998
    Date of Patent: May 30, 2000
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Hirohiko Tsuzuki, Yoshio Inagaki
  • Patent number: 6027870
    Abstract: An infrared-sensitive photothermographic material comprising light-sensitive silver halide grains and a sensitizing dye having a particular structural formula.
    Type: Grant
    Filed: April 15, 1997
    Date of Patent: February 22, 2000
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Hirohiko Tsuzuki, Yoshio Inagaki
  • Patent number: 5998125
    Abstract: A photothermographic material comprising at least one layer containing photosensitive silver halide grains on a support further contains a mono-, tri- or penta-methine cyanine dye having a thienyl or arylthio substituent. The material shows low fog, high sensitivity, and improved age stability.
    Type: Grant
    Filed: October 15, 1997
    Date of Patent: December 7, 1999
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Yoshio Inagaki, Hirohiko Tsuzuki