Abstract: Provided is a substance capable of effectively suppressing cancer metastasis or a pharmaceutical composition that effectively acts on an inflammatory disease. The pharmaceutical composition is a pharmaceutical composition containing, as an active ingredient, an antibody or an antibody fragment thereof having antigen-binding activity for an S100A8/A9 heterodimer, and blocks interaction between S100A8/A9 and a group of receptors therefor, to thereby strongly suppress cancer metastasis both in vitro and in vivo, or alleviate inflammation. That is, the anti-S100A8/A9 antibody or the antibody fragment thereof can strongly suppress cancer metastasis or alleviate inflammation, by virtue of its blocking action on the interaction between S100A8/A9 and the group of receptors therefor.

Abstract: A substrate fixing device includes a baseplate, an electrostatic attraction member, and an electrode pin. The baseplate includes a metallic member in which a through hole is famed. The electrostatic attraction member is over a surface of the baseplate and includes an attraction electrode. The electrode pin is inserted through the through hole to be connected to the attraction electrode. A recess communicating with the through hole is formed in the surface of the metallic member with the through hole being within the recess in a plan view from a direction perpendicular to the surface of the metallic member.

Abstract: A robot system (1) includes the robot (10), a motion sensor (11), a surrounding environment sensor (12, 13), an operation apparatus (21), a learning control section (41), and a relay apparatus (30). The robot (10) performs work based on an operation command. The operation apparatus (21) detects and outputs an operator-operating force applied by the operator. The learning control section (41) outputs a calculation operating force. The relay apparatus (30) outputs the operation command based on the operator-operating force and the calculation operating force. The learning control section (41) estimates and outputs the calculation operating force by using a model constructed by performing the machine learning of the operator-operating force, the surrounding environment data, the operation data, and the operation command based on the operation data and the surrounding environment data outputted by the sensors (11 to 13), and the operation command outputted by the relay apparatus (30).

Abstract: A controller of a robot system performs first control of controlling a robot arm in accordance with an operation with an operator to thereby cause an end effector to apply a treatment to an object and of recording trajectory data and second control of controlling the robot arm based on the trajectory data recorded in the first control to thereby move the end effector such that the end effector reproduces a moving trajectory and applies a treatment to the object. In the second control, in controlling the robot arm based on the trajectory data, the controller controls a pressing force of the end effector against the object.

Abstract: A robot system includes a manipulating force detector configured to detect a manipulating force given to an operation end by an operator, a reaction-force detector configured to detect a reaction force given to a work end or a workpiece held by the work end, a system controller configured to generate an operating command of a master arm and generate an operating command of a slave arm based on the manipulating force and the reaction force, a master-side control part configured to control the master arm, and a slave-side control part configured to control the slave arm. The system controller has an exaggerated expresser configured to exaggeratedly present an operating feel to the operator who operates the operation end in a reaction-force sudden change state that is a state in which the reaction force changes rapidly with time.

Abstract: A fixing device includes a tubular body that forms a nip with a pressure member to fix a recording material onto a recording medium, a heater inside the tubular body and facing a heated region of the tubular body in a first direction, and a heat conductive member that has a thermal conductivity larger in a second direction crossing the first direction and parallel to an axial direction of the tubular body than in the first direction. The heat conductive member includes an end portion and a central portion along the second direction, and the end portion has a higher density than the central portion.

Abstract: A master-slave system includes: a master unit including an operation end, an operation detector that detects operational information inputted by a force being applied to the operation end, and a force applier that gives a force to the operation end; a slave unit including an action part, and an operation part that moves the action part; and a control device. The control device outputs, according to a regulating condition and the operational information, a command for causing the operation part to operate the action part to carry out operation reflecting the regulating condition. The control device outputs, according to the regulating condition, a command for causing the force applier to give a force to the operation end against the input to the operation end that commands the given movement of the action part.

Abstract: An electronic circuit including: a circuit board; a temperature detection element mounted on the circuit board to detect an ambient temperature; and a circuit element mounted on the circuit board and generating heat in conjunction with circuit operation. The circuit board has a conductive pattern with a heat transfer property that is electrically connected to any terminal of the circuit element and transfers the heat generated by the circuit element. The conductive pattern with a heat transfer property is formed in an area outside a range within a predetermined distance from the temperature detection element. In the case where the temperature detection element is electrically connected to the conductive pattern with a heat transfer property, the connection is made via a linear wiring pattern or a linear wiring member.

Abstract: A master-slave system includes a master unit, a slave unit, and a control device. The control device includes first circuitry that determines a first relationship that is a relationship between a slave coordinate system and an object coordinate system, second circuitry that determines a second relationship that is a relationship between a master coordinate system and the object coordinate system, and third circuitry that outputs an operational command for causing the slave unit to operate according to operational information of the master unit, the first relationship, and the second relationship. When the object coordinate system is moved, the first circuitry newly determines the first relationship after the movement based on the moved object coordinate system and the slave coordinate system, and the second-circuitry determines the second relationship after the movement, as a relationship similar to the second relationship before the movement.

Abstract: A robot system includes a slave unit including a slave-side force detector configured to detect a direction and a magnitude of a reaction force acting on a workpiece held by a work end of a slave arm, a master unit including a master-side force detector configured to detect a direction and a magnitude of an operating force applied by an operator to an operation end of a master arm, and a system controller configured to generate a slave operational command and a master operational command based on the operating force and the reaction force. The system controller includes a regulator configured to correct a moving direction of the work end so that the movement of the work end in a pressing direction of an object is regulated when the reaction force exceeds an acceptable value set beforehand.

Abstract: A robot system includes a slave unit including a slave arm having a working end, a slave arm actuator configured to drive the slave arm, and a slave-side controller configured to control the slave arm actuator based on a slave operating command for defining a target position of the working end, a master unit including a master arm having a manipulation end into which the content of manipulation is inputted by an operator, and a system controller configured to generate the slave operating command based on the content of manipulation inputted into the manipulation end. When a command corresponding to the content of manipulation is a command corresponding to a limit equivalent range corresponding to a limit of operation of at least one of the slave arm and the master arm, the system controller performs processing to give perception to the operator.

Abstract: A remote control robot system includes a slave arm configured to perform a given work, a master arm having a motor configured to drive a joint, and configured to receive from an operator an operation to manipulate the slave arm, an instruction generating module configured to generate an instruction to apply to the master arm an imaginary external force in a given direction that is independent from a force received by the slave arm from the exterior, and a motor controller configured to supply, to the motor, drive current corresponding to the instruction sent from the instruction generating module.

Abstract: A robot system (1) includes the robot (10), a motion sensor (11), a surrounding environment sensor (12, 13), an operation apparatus (21), a learning control section (41), and a relay apparatus (30). The robot (10) performs work based on an operation command. The operation apparatus (21) detects and outputs an operator-operating force applied by the operator. The learning control section (41) outputs a calculation operating force. The relay apparatus (30) outputs the operation command based on the operator-operating force and the calculation operating force. The learning control section (41) estimates and outputs the calculation operating force by using a model constructed by performing the machine learning of the operator-operating force, the surrounding environment data, the operation data, and the operation command based on the operation data and the surrounding environment data outputted by the sensors (11 to 13), and the operation command outputted by the relay apparatus (30).

Abstract: A refrigerant flow path switch arranged between an outdoor device and each of multiple indoor devices controls a refrigerant flow and is provided with a housing; a refrigerant flow path switching circuit having multiple refrigerant flow path switching circuits, wherein each refrigerant flow path switching circuit includes a high/low pressure gas pipe, a low pressure gas pipe, a high/low pressure electric valve provided at the high/low pressure gas pipe, and a low pressure electric valve provided at the low pressure gas pipe. A liquid pipe assembly is arranged in the housing and has multiple liquid pipes connected to the multiple indoor devices. A first divider plate is provided between adjacent ones of the refrigerant flow path switching circuits and divides an internal space of the housing such that a space divided by the first divider plate is in a substantially cubic shape, which is filled with a foaming agent.

Abstract: In order to enable a drain pan to be visually checked for contamination without requiring a complicated operation, the present invention is configured so as to be equipped with: a housing; a drain pan provided inside the housing; a drain pump for pumping up drain water accumulated in the drain pan; an opening provided in a side surface of the housing; and a cover member attached to the opening and covering the opening. When the cover member is detached from the opening at least a portion of the drain pan can be viewed from the opening.

Abstract: A robot system includes a slave unit including a slave-side force detector configured to detect a direction and a magnitude of a reaction force acting on a workpiece held by a work end of a slave arm, a master unit including a master-side force detector configured to detect a direction and a magnitude of an operating force applied by an operator to an operation end of a master arm, and a system controller configured to generate a slave operational command and a master operational command based on the operating force and the reaction force. The system controller includes a regulator configured to correct a moving direction of the work end so that the movement of the work end in a pressing direction of an object is regulated when the reaction force exceeds an acceptable value set beforehand.

Abstract: A robot system includes a manipulating force detector configured to detect a manipulating force given to an operation end by an operator, a reaction-force detector configured to detect a reaction force given to a work end or a workpiece held by the work end, a system controller configured to generate an operating command of a master arm and generate an operating command of a slave arm based on the manipulating force and the reaction force, a master-side control part configured to control the master arm, and a slave-side control part configured to control the slave arm. The system controller has an exaggerated expresser configured to exaggeratedly present an operating feel to the operator who operates the operation end in a reaction-force sudden change state that is a state in which the reaction force changes rapidly with time.

Abstract: A remote control robot system includes a slave arm configured to perform a given work, a master arm having a motor configured to drive a joint, and configured to receive from an operator an operation to manipulate the slave arm, an instruction generating module configured to generate an instruction to apply to the master arm an imaginary external force in a given direction that is independent from a force received by the slave arm from the exterior, and a motor controller configured to supply, to the motor, drive current corresponding to the instruction sent from the instruction generating module.

Abstract: A refrigerant flow path switch arranged between an outdoor device and each of multiple indoor devices controls a refrigerant flow and is provided with a housing; a refrigerant flow path switching circuit having multiple refrigerant flow path switching circuits, wherein each refrigerant flow path switching circuit includes a high/low pressure gas pipe, a low pressure gas pipe, a high/low pressure electric valve provided at the high/low pressure gas pipe, and a low pressure electric valve provided at the low pressure gas pipe. A liquid pipe assembly is arranged in the housing and has multiple liquid pipes connected to the multiple indoor devices. A first divider plate is provided between adjacent ones of the refrigerant flow path switching circuits and divides an internal space of the housing such that a space divided by the first divider plate is in a substantially cubic shape, which is filled with a foaming agent.

Abstract: In order to enable a drain pan to be visually checked for contamination without requiring a complicated operation, the present invention is configured so as to be equipped with: a housing; a drain pan provided inside the housing; a drain pump for pumping up drain water accumulated in the drain pan; an opening provided in a side surface of the housing; and a cover member attached to the opening and covering the opening. When the cover member is detached from the opening at least a portion of the drain pan can be viewed from the opening.