Patents by Inventor Hiroki Nishita

Hiroki Nishita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell death inducing agent for cells having BRAF gene mutation, growth suppressing agent for same cells and pharmaceutical composition for therapy of diseases caused by growth defect of same cells
    Patent number: 10570396
    Abstract: Cell death is induced and/or cell growth is suppressed for a cell having a mutation in the BRAF gene. A drug suppressing GST-? is comprised as an active ingredient.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: February 25, 2020
    Assignee: Nitto Denko Corporation
    Inventors: Yoshiro Niitsu, Hiroki Nishita
  • CELL DEATH INDUCING AGENT FOR CELLS HAVING BRAF GENE MUTATION, GROWTH SUPPRESSING AGENT FOR SAME CELLS AND PHARMACEUTICAL COMPOSITION FOR THERAPY OF DISEASES CAUSED BY GROWTH DEFECT OF SAME CELLS
    Publication number: 20180135058
    Abstract: Cell death is induced and/or cell growth is suppressed for a cell having a mutation in the BRAF gene. A drug suppressing GST-? is comprised as an active ingredient.
    Type: Application
    Filed: April 15, 2016
    Publication date: May 17, 2018
    Inventors: Yoshiro NIITSU, Hiroki NISHITA
  • Apoptosis-inducing agent
    Patent number: 9914983
    Abstract: The purpose of the present invention is to provide a composition for effectively inducing apoptosis and/or proliferation inhibition in a cell, and a method using the same. An agent for inducing apoptosis that comprises as active ingredients a drug inhibiting GST-? and a drug inhibiting Akt; a medicinal composition comprising the same; a method for treating a disease caused by abnormality in apoptosis using the same, etc.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: March 13, 2018
    Assignee: Nitto Denko Corporation
    Inventors: Yoshiro Niitsu, Hiroki Nishita, Hiroyuki Tanaka
  • METHODS AND COMPOSITIONS FOR TREATING MALIGNANT TUMORS ASSOCIATED WITH KRAS MUTATION
    Publication number: 20160186183
    Abstract: This invention provides methods and compositions for preventing, treating or ameliorating one or more symptoms of a malignant tumor associated with KRAS mutation in a mammal in need thereof, by identifying a tumor cell in the mammal, the tumor cell comprising at least one of: (i) a mutation of the KRAS gene, and (ii) an aberrant expression level of KRAS protein; and administering to the mammal a therapeutically effective amount of a composition comprising one or more RNAi molecules that are active in reducing expression of GST-?.
    Type: Application
    Filed: December 28, 2015
    Publication date: June 30, 2016
    Inventors: Yoshiro Niitsu, Kenjirou Minomi, Hiroki Nishita, Yusuke Nakashima, Miyono Miyazaki, Keiko Kajiwara, Jihua Liu, Li Wang, Jens Harborth, Bharat Majeti, Roger Adami, Wenbin Ying
  • APOPTOSIS-INDUCING AGENT
    Publication number: 20150328248
    Abstract: The purpose of the present invention is to provide a composition for effectively inducing apoptosis and/or proliferation inhibition in a cell, and a method using the same. An agent for inducing apoptosis that comprises as active ingredients a drug inhibiting GST-? and a drug inhibiting Akt; a medicinal composition comprising the same; a method for treating a disease caused by abnormality in apoptosis using the same, etc.
    Type: Application
    Filed: December 20, 2013
    Publication date: November 19, 2015
    Inventors: Yoshiro NIITSU, Hiroki NISHITA, Hiroyuki TANAKA
  • APOPTOSIS-INDUCING AGENT
    Publication number: 20140315975
    Abstract: This invention relates to: a novel use of GST-? and GST-? suppressing agents; an apoptosis-inducing agent containing as active components a drug that suppresses GST-? and a drug that suppresses autophagy; a medical composition containing said agent; and a method using said medical composition for treating diseases associated with abnormal apoptosis.
    Type: Application
    Filed: June 21, 2011
    Publication date: October 23, 2014
    Applicant: NITTO DENKO CORPORATION
    Inventors: Yoshiro Niitsu, Hiroki Nishita