Abstract: A high-lift device includes a flap disposed at a leading edge of a wing, and configured to be retracted in the lower surface and extended toward of the leading edge; a first rotary shaft and a second rotary shaft, the axial direction of the rotary shafts being disposed along the spanwise direction of the wing, respectively; a first link mechanism connected to the first rotary shaft and the flap; and a second link mechanism connected to the second rotary shaft and the flap. When the first link mechanism is driven with the first rotary shaft, the flap is retracted in the lower surface of the leading edge or is extended toward the front of the leading edge. When the second link mechanism is driven with the second rotary shaft, the position or the angle of the flap moved by the first link mechanism is changed.

Abstract: It is an object of the present invention to provide a film-forming composition for skin (such as a film-type skin protectant or a film-type skin topical agent) that does not contain a lower monohydric alcohol such as ethanol or isopropanol, is excellent in quick-drying properties and water resistance, is less sticky, and is excellent in feeling of use. The present invention relates to a film-forming composition for skin which contains a specific acrylic polymer, a plasticizer and water and is substantially free of a lower monohydric alcohol such as ethanol or isopropanol. The composition of the present invention is extremely useful for treatment of chronic skin diseases (that is, skin diseases in which skin barrier function is deteriorated) represented by hand eczema, atopic dermatitis, and the like.

Abstract: A high-lift device includes a flap disposed at a leading edge of a wing, and configured to be retracted in the lower surface and extended toward of the leading edge; a first rotary shaft and a second rotary shaft, the axial direction of the rotary shafts being disposed along the spanwise direction of the wing, respectively; a first link mechanism connected to the first rotary shaft and the flap; and a second link mechanism connected to the second rotary shaft and the flap. When the first link mechanism is driven with the first rotary shaft, the flap is retracted in the lower surface of the leading edge or is extended toward the front of the leading edge. When the second link mechanism is driven with the second rotary shaft, the position or the angle of the flap moved by the first link mechanism is changed.

Abstract: The present invention aims to provide a cyclosporine external preparation showing improved transdermal absorbability of cyclosporine. The present invention provides an external preparation containing cyclosporine and a ketone.

Abstract: The present invention is intended to provide a cyclosporine external preparation that improves transdermal absorption of cyclosporine. The present invention provides an external preparation containing cyclosporine, ethanol, and a fatty acid monoester.

Abstract: The present invention aims to provide a cyclosporine external preparation showing improved transdermal absorbability of cyclosporine. The present invention provides an external preparation containing cyclosporine and a ketone.

Abstract: The present invention provides a dermal composition comprising a polymeric reversed micelle that allows a water-soluble drug to be efficiently encapsulated and that is superior in percutaneous absorptiveness and very safe, and provides a method that can produce the composition in simple steps. The dermal composition comprises a polymeric reversed micelle composed of an amphipathic polymer having a hydrophilic segment and a hydrophobic segment, wherein the polymeric reversed micelle has a configuration in which the hydrophilic segment is the core and the hydrophobic segment is the shell, and a water-soluble drug is encapsulated therein. The composition can be produced by blending an oil phase comprising the amphipathic polymer in an oily base agent with an aqueous phase comprising the water-soluble drug in an aqueous solvent, or by blending an oily base agent with an aqueous phase comprising the amphipathic polymer and the water-soluble drug in an aqueous solvent.