Abstract: Provided is a compound that can promote angiogenesis by inhibiting the function of TSP1, and is useful for the treatment or prophylaxis of diseases such as critical limb ischemia.

Abstract: A thickener is provided comprising an anionic polyacrylamide group containing at least two anionic polyacrylamides having different degrees of anionization, and a water-soluble cellulose ether. When added to a hydraulic composition, the thickener is effective for improving flow while maintaining rheological properties.

Abstract: Provided is a compound that can promote angiogenesis by inhibiting the function of TSP1, and is useful for the treatment or prophylaxis of diseases such as critical limb ischemia.

Abstract: A thickener is provided comprising an anionic polyacrylamide group containing at least two anionic polyacrylamides having different degrees of anionization, and a water-soluble cellulose ether. When added to a hydraulic composition, the thickener is effective for improving flow while maintaining rheological properties.

Abstract: It has been found that a compound of the general formula (I) having an isoxazole skeleton has excellent inhibitory activity against mutant IDH1 protein and inhibits the production of 2-HG by this protein, while the compound is also capable of effectively inhibiting the growth of various tumors expressing the protein. In the formula, R1, R2, R3, Y, and Z are as defined in claim 1.

Abstract: It has been found that a compound of the general formula (I) having an isoxazole skeleton has excellent inhibitory activity against mutant IDH1 protein and inhibits the production of 2-HG by this protein, while the compound is also capable of effectively inhibiting the growth of various tumors expressing the protein. In the formula, R1, R2, R3, Y, and Z are as defined in claim 1.

Abstract: Cellulose ether powder is prepared in a safe and easy way by first adding a surfactant solution to surfaces of water-soluble cellulose ether particles, and then adding a tannin solution thereto. The powder thus prepared is free of bitterness and readily dissolvable in cold water without forming clumps.

Abstract: A compound represented by formula (I) having mTOR inhibitory activity or a pharmacologically acceptable salt thereof.

Abstract: Cellulose ether powder is prepared in a safe and easy way by first adding a surfactant solution to surfaces of water-soluble cellulose ether particles, and then adding a tannin solution thereto. The powder thus prepared is free of bitterness and readily dissolvable in cold water without forming clumps.

Abstract: A compound represented by formula (I) having mTOR inhibitory activity or a pharmacologically acceptable salt thereof.

Abstract: A compound represented by formula (I) having mTOR inhibitory activity or a pharmacologically acceptable salt thereof.

Abstract: A fuel tank is provided which suppresses wave motion on the liquid surface of fuel which occurs when a vehicle accelerates or decelerates. A front wall and/or a rear wall of the fuel tank includes a plurality of steps formed integrally therewith. The liquid surface of the fuel striking the steps is dispersed, and wave motion on the liquid surface is thereby suppressed. Since the steps are formed in the front wall and/or the rear wall of the fuel tank, the volume of the tank is not reduced.

Abstract: A fuel tank is provided which suppresses wave motion on the liquid surface of fuel which occurs when a vehicle accelerates or decelerates. A front wall and/or a rear wall of the fuel tank includes a plurality of steps formed integrally therewith. The liquid surface of the fuel striking the steps is dispersed, and wave motion on the liquid surface is thereby suppressed. Since the steps are formed in the front wall and/or the rear wall of the fuel tank, the volume of the tank is not reduced.

Abstract: A rod-like body made of a rubber material having an outside diameter which is substantially equal to the inside diameter of the guard pipe or an unexpanded resin material having a quality that the resin material expands sufficiently when heated in a paint baking process for the guard pipe is inserted, as a vibration damping material, into the interior of the guard pipe before the pipe is worked. Due to this, since the guard pipe can be made difficult to vibrate without making any substantial changes to the conventional vehicle body structure, the invention is effective in reducing noise generated while a vehicle is running without entraining a remarkable increase in production costs.