Patents by Inventor Hironoshin Kitagawa

Hironoshin Kitagawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hyaluronic acid gel, process for producing the same, and medical material containing the same
    Patent number: 7014860
    Abstract: Production of a hyaluronic acid gel, which comprises keeping hyaluronic acid in water at a hyaluronic acid concentration of at least 5 wt % in the presence of an acid component in an amount at least equimolar with the carboxyl groups in the hyaluronic acid.
    Type: Grant
    Filed: February 3, 2000
    Date of Patent: March 21, 2006
    Assignee: Denki Kagaku Kogyo Kabushiki Kaisha
    Inventors: Masatoshi Kawata, Akio Okamoto, Yoshiaki Miyata, Kazuhiro Ohshima, Osamu Yamamoto, Teruzou Miyoshi, Kazuhiko Arai, Hironoshin Kitagawa, Toshihiko Umeda, Hiroshi Kaneko
  • Hyaluronic acid gel, process for the preparation thereof and medical materials containing the same
    Patent number: 6635267
    Abstract: A gel made of hyaluronic acid alone which is hardly soluble in a neutral aqueous solution and has fluidity enough to be easily ejectable from an injector.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: October 21, 2003
    Assignee: Denki Kagaku Kogyo Kabushiki Kaisha
    Inventors: Teruzou Miyoshi, Hironoshin Kitagawa, Kazuhiko Arai, Hiroshi Kaneko, Toshihiko Umeda
  • Hyaluronic acid and its salt for treating skin diseases
    Patent number: 5728391
    Abstract: An agent for treating a skin disease selected from the group consisting of a contact dermatitis treating agent, a xerosis senilis treating agent, an asteatosis treating agent, a housewives eczema treating agent, a keratosis treating agent, an eczema chronicum treating agent, a miliaria treating agent and a diaper rash treating agent, which contains hyaluronic acid and/or its salt having an average molecular weight of from 800,000 to 4,000,000, as an active ingredient.
    Type: Grant
    Filed: December 5, 1995
    Date of Patent: March 17, 1998
    Assignee: Denki Kagaku Kogyo Kabushiki Kaisha
    Inventors: Hitoshi Ikeya, Hironoshin Kitagawa
  • Method for producing sodium hyaluronate by fermentation method
    Patent number: 4946780
    Abstract: A method for producing sodium hyaluronate by a fermentation method comprises culturing a mutant strain FM 100 derived from Streptococcus equi and partially free from auxotrophy to thereby stably produce sodium hyaluronate and accumulating the hyaluronate. A method for producing sodium hyaluronate by a fermentation method comprises culturing a mutant strain FM 300 derived from Streptococcus equi and partially free from auxotophy to thereby stably produce sodium hyaluronate and accumulating the hyaluronate.
    Type: Grant
    Filed: May 4, 1989
    Date of Patent: August 7, 1990
    Assignee: Denkl Kagaku Kogyo Kabushiki Kaisha
    Inventors: Masamichi Hashimoto, Haruhisa Saegusa, Susumu Chiba, Hironoshin Kitagawa, Teruzo Miyoshi
  • Method for preventing deterioration of starch-containing foods
    Patent number: 4748032
    Abstract: A method for preventing deterioration of a food is disclosed wherein an oosaccharide originating from agar or carrageenan or both agar and carrageenan are added to the food. The method is effective to prevent deterioration of foods attributed to retrogradation of gelatinized starch.
    Type: Grant
    Filed: March 13, 1987
    Date of Patent: May 31, 1988
    Assignee: The Japanese Research and Development Association for Bioreactor System
    Inventors: Toshiaki Kono, Takahisa Tokunaga, Goichi Yamaguchi, Hironoshin Kitagawa, Tetsuo Hiraga
  • Immobilization of enzymes on granular gelatin
    Patent number: 4411999
    Abstract: A process for producing an immobilized enzyme composition comprises simultaneously reacting a non-proteolytic enzyme and a water soluble-multifunctional reagent with a non-hardened granular gelatin in an aqueous medium wherein the reacting is carried out in the presence of a water-soluble protein polymer compound in an amount of from 0.01 to 2 parts by weight relative to one part of the non-proteolytic enzyme. The non-proteolytic enzyme forms a uniform film on the surface of the granular gelatin and the bond between the non-proteolytic enzyme and the granular gelatin is strengthened by the water soluble protein polymer.
    Type: Grant
    Filed: September 29, 1981
    Date of Patent: October 25, 1983
    Assignee: Denki Kagaku Kogyo Kabushiki Kaisha
    Inventors: Shigeki Shigesada, Hironoshin Kitagawa, Toshio Mihara, Yoshiaki Ishimatsu
  • Process for producing immobilized enzyme compositions
    Patent number: 4205128
    Abstract: Immobilized enzyme compositions for industrial use are produced by reacting an enzyme and/or enzyme-containing microorganism cells with an anion-exchange high molecular substance having a quaternary pyridine ring in the molecule, and then subjecting the reaction products to molding and drying in a molding machine. A polyfunctional crosslinking agent may be added at any stage of the process. The immobilized enzyme compositions thus prepared can be packed in a reactor of an industrial scale for continuous enzyme reaction.
    Type: Grant
    Filed: August 25, 1978
    Date of Patent: May 27, 1980
    Assignee: Denki Kagaku Kogyo Kabushiki Kaisha
    Inventors: Yoshiaki Ishimatsu, Shigeki Shigesada, Hiroyasu Suzuki, Hironoshin Kitagawa, Shoji Kimura