Patents by Inventor Hiroo Wada
Hiroo Wada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240287239Abstract: Provided is a two-pack type urethane molding material for optical lenses including a main agent containing an isocyanate-terminated prepolymer which is an intermediate product of a polyurethane production reaction by an alicyclic diisocyanate and a polyhydroxy compound; and a curing agent containing an aromatic diamine of dimethylthiotoluenediamine (DMTDA), diethyltoluenediamine (DETDA) or a mixture of these. Also, a polyurethane resin optical lens is provided which is constituted by a cast molded body using the two-pack type urethane molding material.Type: ApplicationFiled: March 14, 2022Publication date: August 29, 2024Applicant: TALEX CO., LTD.Inventors: Hiroo TAMURA, Kenzo WADA
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Publication number: 20200386767Abstract: Provided are an analytical method and apparatus using fingerprints on the basis of the types and expression levels of expressed trace proteins and/or peptides contained in living tissue and/or biological fluid. The present invention relates to a method and apparatus for analyzing the status of living tissue and/or biological fluid by binding a specific fluorogenic reagent (such as DAABD-Cl) to expressed trace proteins and/or peptides contained in living tissue and/or biological fluid without degradation treatment followed by precisely detecting and separating by nano-liquid chromatography, and subsequently continuously and quantitatively measuring the separated and purified fluorescent labelled proteins and/or peptides using a fluorescence detector. The use of a nano-liquid chromatograph having a fluorescence detector makes it possible to obtain profiles of expressed trace proteins and/or peptides contained in living tissue and/or biological fluid.Type: ApplicationFiled: June 11, 2019Publication date: December 10, 2020Inventors: Hiroshi Kobayashi, Hiroo Wada, Kazuhiro Imai
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Patent number: 9097693Abstract: The invention provides a method for simple, rapid and inexpensive analysis of drugs such as nicotine and other drugs which are accumulated in biological samples of addictive drugger of tobacco, stimulant drug and the like. The method comprises the steps of introducing the biological sample into an injection needle, inserting the needle into an injector of a chromatograph and injecting a carrier into the needle to conduct chromatography treatment.Type: GrantFiled: March 14, 2006Date of Patent: August 4, 2015Assignees: SHINWA CHEMICAL INDUSTRIES, LTD., NATIONAL UNIVERSITY CORPORATION TOYOHASHI UNIVERSITY OF TECHNOLOGY, NIPPON MEDICAL SCHOOL FOUNDATIONInventors: Hiroo Wada, Kiyokatsu Jinno, Yoshihiro Saito, Youkichi Ohno, Makiko Hayashida
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Publication number: 20120034566Abstract: A micro-channel device provided in a solution analysis system using pressure liquid feed comprises a plurality of straight-line channels and curved channels connecting the ends of the neighboring straight-line channels. The width w of each curved channel is smaller than the width t of each straight-line channel. The radius of curvature r of each curved channel is set so that the value of a expressed by formula (1) is equal to or smaller than the value of a at a local maximum point of the theoretical step height H expressed by formula (2) and based on the shape of the curved channel. a=w/r??(1) H = u c ? w 2 64 ? ? ? ? D m × a 2 ? ( a + 2 ) a + 1 ( 2 ) Where, w is a width of the curved channel, uc is a channel passing speed of a solution in the curved channel, ? is a molecular diffusion inhibition factor by basic members present in the curved channel, and Dm is a molecular diffusion coefficient of the solution.Type: ApplicationFiled: March 29, 2010Publication date: February 9, 2012Applicants: TOKYO ELECTRON LIMITED, SHINWA CHEMICAL INDUSTRIES LTD.Inventors: Hiroo Wada, Hiroshi Tamura, Hiroshi Kobayashi, Tomofumi Kiyomoto, Seokhyoung Hong
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Patent number: 8101073Abstract: The present invention relates to a separating agent for solid-phase extraction which comprises core particles of a base material; a hydrophilic polymer layer formed on the surface of the particles; and a hydrophobic polymer layer formed on the surface of the hydrophilic polymer layer. The separating agent can be used in a cartridge or a column for solid-phase extraction and the latter can in turn be used in a variety of methods such as a method for concentrating a subject to be separated; a method for removing impurities; a method for solid-phase extraction of an environmental, medicinal and/or biological samples; and a method for pre-treating a protein component-containing sample.Type: GrantFiled: August 31, 2005Date of Patent: January 24, 2012Assignee: Shinwa Chemical Industries, Ltd.Inventors: Hiroo Wada, Kosuke Fukuzawa
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Patent number: 8043564Abstract: Described is a copolymer of methacrylic acid and ethylene glycol dimethacrylate which does not have any specificity to general organic solvents, can thus adsorb wide variety of the organic solvents, shows almost no desorption-adsorption hysteresis and therefore, is excellent in desorption characteristics. Also described is a method for the preparation of the copolymer; an adsorbent or a concentrating medium comprising the copolymer; a loop used in an injector for chromatography which is packed with the adsorbent or concentrating medium; a needle for solid-phase microextraction (SPME) which is packed with the adsorbent or concentrating medium; a kit for the preparation of a sample comprising the needle for SPME; a method for concentrating a sample; and a method for analyzing an analyte present in a sample.Type: GrantFiled: October 14, 2003Date of Patent: October 25, 2011Assignee: Shinwa Chemical Industries, Ltd.Inventors: Hiroo Wada, Kenzo Kotera, Hisashi Matsuura, Kiyokatsu Jinno, Yoshihiro Saito
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Publication number: 20080293151Abstract: Provided are a simple method for analyzing aldehydes and ketones in a sample, which does not require a complicated operation such as extraction with a solvent and concentration of the extract; and an analytical apparatus and a fiber-packed needle which are used in the analytical method. Also provided a fiber coated with hydrochloride or sulfate of 2,4-dinitrophenylhydrazine; a needle for microextraction in which the fibers are packed; the analytical apparatus including this needle and a suction device; the method for analyzing aldehydes and ketones in a sample, characterized by comprising sucking the sample through the needle in this analytical apparatus to allow the aldehydes and ketones in the sample to react with 2,4-dinitrophenylhydrazine, thereby converting them to the corresponding 2,4-dinitrophenylhydrazones; desorbing the 2,4-dinitrophenylhydrazones; and introducing the desorbed 2,4-dinitrophenylhydrazones into a chromatograph to analyze them.Type: ApplicationFiled: August 1, 2008Publication date: November 27, 2008Inventor: Hiroo WADA
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Publication number: 20080193962Abstract: The invention provides a method for simple, rapid and inexpensive analysis of drugs such as nicotine and other drugs which are accumulated in biological samples of addictive drugger of tobacco, stimulant drug and the like. The method comprises the steps of introducing the biological sample into an injection needle, inserting the needle into an injector of a chromatograph and injecting a carrier into the needle to conduct chromatography treatment.Type: ApplicationFiled: March 14, 2006Publication date: August 14, 2008Inventors: Hiroo Wada, Kiyokatsu Jinno, Yoshihiro Saito, Youkichi Ohno, Makiko Hayashida
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Publication number: 20080070795Abstract: The present invention aims to provide a technique for stably immobilizing a probe on a carrier The present invention provides a linker compound represented by formula (1): wherein A represents a hydrogen atom, another substituent, a sugar, or a derivative thereof.Type: ApplicationFiled: September 7, 2007Publication date: March 20, 2008Applicants: KYOTO UNIVERSITY, SHINWA CHEMICAL INDUSTRIES, LTD., NGK Insulators, Ltd.Inventors: Keisuke Makino, Tsutomu Kodaki, Seiya Watanabe, Seung Pack, Mitsuru Nonogawa, Hiroo Wada, Yasuko Yoshida, Kazunari Yamada
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Patent number: 7211189Abstract: A separation column for chromatography or a medium for solid phase extraction, which comprises a hollow capillary and a collected body packed in the hollow capillary and serving as a stationary phase, the collected body comprising long fibers having an adsorbing ability selective towards a target solute and arranged in the axial direction of the capillary, and a sample injection system which comprises the foregoing hollow capillary incorporated into a loop of a valve or a passage connecting two valves, the valve(s) being used as an injector for the chromatography. The use of the polymeric long fibers, which have chemical structures specially designed so that they can specifically interact with a target substance (a solute or an analyte) to be analyzed, permits the selective or preferential extraction and/or concentration of the solute.Type: GrantFiled: June 23, 2004Date of Patent: May 1, 2007Assignees: Shinwa Chemical Industries, Ltd.Inventors: Kiyokatsu Jinno, Yoshihiro Saito, Tsutomu Takeichi, Hiroo Wada
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Publication number: 20060043022Abstract: The present invention relates to a separating agent for solid-phase extraction which comprises core particles of a base material; a hydrophilic polymer layer formed on the surface of the particles; and a hydrophobic polymer layer formed on the surface of the hydrophilic polymer layer. The separating agent can be used in a cartridge or a column for solid-phase extraction and the latter can in turn be used in a variety of methods such as a method for concentrating a subject to be separated; a method for removing impurities; a method for solid-phase extraction of an environmental, medicinal and/or biological samples; and a method for pre-treating a protein component-containing sample.Type: ApplicationFiled: August 31, 2005Publication date: March 2, 2006Applicant: Shinwa Chemical Industries, Ltd.Inventors: Hiroo Wada, Kosuke Fukuzawa
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Publication number: 20050058774Abstract: A method for coating the surface of a solid material with fine particles of a metal or a metal compound is provided. The method comprises the step of bringing a solid material into close contact with fine particles of a metal or a metal compound to which a compound having at least two mercapto groups is bonded, under light-shielding conditions or under the irradiation with light rays other than laser light rays. The method does not require the use of any specially designed device. It permits the immobilization of fine particles on the surface of a solid within an appropriate period of time, the immobilization thereof even in the environment in which any light cannot be used, the production of a desired fine particle-coated solid material at a low cost and the uniform coating of even a solid material having a wide area with fine particles.Type: ApplicationFiled: September 10, 2004Publication date: March 17, 2005Applicant: Shinwa Chemical Industries, Ltd.Inventor: Hiroo Wada
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Publication number: 20050000874Abstract: A separation column for chromatography or a medium for solid phase extraction, which comprises a hollow capillary and a collected body packed in the hollow capillary and serving as a stationary phase, the collected body comprising long fibers having an adsorbing ability selective towards a target solute and arranged in the axial direction of the capillary, and a sample injection system which comprises the foregoing hollow capillary incorporated into a loop of a valve or a passage connecting two valves, the valve(s) being used as an injector for the chromatography. The use of the polymeric long fibers, which have chemical structures specially designed so that they can specifically interact with a target substance (a solute or an analyte) to be analyzed, permits the selective or preferential extraction and/or concentration of the solute.Type: ApplicationFiled: June 23, 2004Publication date: January 6, 2005Applicants: Shinwa Chemical Industries, Ltd.Inventors: Kiyokatsu Jinno, Yoshihiro Saito, Tsutomu Takeichi, Hiroo Wada
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Patent number: 6780314Abstract: A separation column for chromatography or a medium for solid phase extraction, which comprises a hollow capillary and a collected body packed in the hollow capillary and serving as a stationary phase, the collected body comprising long fibers having an adsorbing ability selective towards a target solute and arranged in the axial direction of the capillary, and a sample injection system which comprises the foregoing hollow capillary incorporated into a loop of a valve or a passage connecting two valves, the valve(s) being used as an injector for the chromatography. The use of the polymeric long fibers, which have chemical structures specially designed so that they can specifically interact with a target substance (a solute or an analyte) to be analyzed, permits the selective or preferential extraction and/or concentration of the solute.Type: GrantFiled: October 31, 2001Date of Patent: August 24, 2004Assignees: Shinwa Chemical Industries, Ltd.Inventors: Kiyokatsu Jinno, Yoshihiro Saito, Tsutomu Takeichi, Hiroo Wada
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Publication number: 20040144715Abstract: The invention provides a carrier or a pre-treating carrier for use in chromatography which comprises a carrier material consisting essentially of a metal compound, capable of reacting with a carboxylic acid compound or a carrier material whose surface is coated with the metal compound and a carboxylic acid compound linked to the surface of the carrier material; and a kit for the preparation of the foregoing carrier for chromatography or pre-treating carrier which comprises the foregoing carrier material and the carboxylic acid compound to be linked to the surface of the carrier material. The use of the carrier for chromatography or pre-treating carrier would permit the achievement of a variety of excellent effects. For instance, the hydrophobic separation field established by, for instance, the octadecyl groups is never eliminated even under weak acidic or alkaline conditions, which leads to long service life.Type: ApplicationFiled: October 21, 2003Publication date: July 29, 2004Applicant: Shinwa Chemical Industries, Ltd.Inventors: Hideyuki Kanehara, Hiroo Wada
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Publication number: 20040091400Abstract: The invention provides a copolymer of methacrylic acid and ethylene glycol dimethacrylate which does not have any specificity to general organic solvents, can thus adsorb wide variety of the organic solvents, shows almost no desorption-adsorption hysteresis and therefore, is excellent in the desorption characteristics.Type: ApplicationFiled: October 14, 2003Publication date: May 13, 2004Applicant: Shinwa Chemical Industries, Ltd.Inventors: Hiroo Wada, Kenzo Kotera, Hisashi Matsuura, Kiyokatsu Jinno, Yoshihiro Saito
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Publication number: 20040007513Abstract: A carrier for chromatography or a carrier for a pre-treatment comprises a carrier material consisting of a metal or a metal compound reactive with the sulfur-containing compound or a carrier material whose surface is coated with the foregoing metal or metal compound; and a sulfur-containing compound bonded to the surface of the foregoing carrier material and a kit for preparing a carrier for chromatography or a carrier for a pre-treatment comprises the foregoing carrier material; and a sulfur-containing compound. This carrier has a hydrophobic field established by groups such as octadecyl groups, which is never eliminated therefrom even under acidic and alkaline conditions; has thus a high separation power and a long service life; can easily be prepared within a short period of time; and therefore, the production cost thereof is quite low.Type: ApplicationFiled: June 3, 2003Publication date: January 15, 2004Applicant: Shinwa Chemical Industries, Ltd.Inventors: Hideyuki Kanehara, Hiroo Wada
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Publication number: 20030224133Abstract: A packing material for chromatography or a packing material for a pre-treatment comprises a packing material consisting of a metal or a metal compound reactive with the sulfur-containing compound or a packing material whose surface is coated with the foregoing metal or metal compound; and a sulfur-containing compound bonded to the surface of the foregoing packing material and a kit for preparing a packing material for chromatography or a packing material for a pre-treatment comprises the foregoing packing material; and a sulfur-containing compound. This packing material has a hydrophobic field established by groups such as octadecyl groups, which is never eliminated therefrom even under acidic and alkaline conditions; has thus a high separation and a long service life; can easily be prepared within a short period of time; and therefore, the production cost thereof is quite low.Type: ApplicationFiled: May 30, 2003Publication date: December 4, 2003Applicant: Shinwa Chemical Industries, Ltd.Inventors: Hideyuki Kanehara, Hiroo Wada
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Publication number: 20020050470Abstract: A separation column for chromatography or a medium for solid phase extraction, which comprises a hollow capillary and a collected body packed in the hollow capillary and serving as a stationary phase, the collected body comprising long fibers having an adsorbing ability selective towards a target solute and arranged in the axial direction of the capillary, and a sample injection system which comprises the foregoing hollow capillary incorporated into a loop of a valve or a passage connecting two valves, the valve(s) being used as an injector for the chromatography. The use of the polymeric long fibers, which have chemical structures specially designed so that they can specifically interact with a target substance (a solute or an analyte) to be analyzed, permits the selective or preferential extraction and/or concentration of the solute.Type: ApplicationFiled: October 31, 2001Publication date: May 2, 2002Applicant: Shinwa Chemical Industries, Ltd.Inventors: Kiyokatsu Jinno, Yoshihiro Saito, Tsutomu Takeichi, Hiroo Wada
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Patent number: 6027648Abstract: An optical isomer separating agent comprises a stationary phase in which the molecular structure of ovomucoid fixed to a carrier is partly modified, or a stationary phase in which ovomucoid having the molecule partly modified is fixed to a carrier is disclosed. A process for producing an optical isomer separating agent comprises the steps of immobilizing ovomucoid on a carrier and modifying the ovomucoid is disclosed. Furthermore a process for producing an optical isomer separating agent comprises the steps of modifying ovomucoid and immobilizing the modified ovomucoid on a carrier is disclosed.Type: GrantFiled: February 25, 1994Date of Patent: February 22, 2000Assignees: Shinwa Chemical Industries, Ltd., Eisai Co., Ltd.Inventors: Jun Haginaka, Hiroo Wada, Hiroya Fujima, Toshinobu Miwa