Abstract: Phenylacetic acid derivatives of the formula: ##STR1## wherein R.sup.1 is hydrogen or ##STR2## wherein R.sup.5 is an alkyl group of 1-6 carbon atoms or an aryl group; R.sup.2 and R.sup.3 are independently hydrogen or an alkyl group of 1-4 carbon atoms; R.sup.4 is hydrogen or an alkyl group of 1-4 carbon atoms, have been found to possess immunomodulating activity.

Abstract: 4-Quinolone derivatives of the present invention are useful for their anti-inflammatory, anti-allergenic, antitussive, expectorant and antithrombotic activity. Pharmaceutical compositions containing said compounds and pharmaceutically acceptable salts thereof and methods of treating humans and animals are described herein.

Abstract: A compound of the formula ##STR1## R.sub.1 is hydrogen, alkali metal, alkaline earth metal, lower alkyl, pivaloyloxymethyl or phthalidyl;R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are the same or different and are hydrogen, halogen, lower alkoxy or ##STR2## wherein R.sub.6 and R.sub.7 are lower alkyl or R.sub.6 and R.sub.7 together with the nitrogen atom to which they are attached form a five- to seven-membered unsubstituted or substituted heterocyclic ring containing said nitrogen atom as the sole hetero atom or containing nitrogen, sulfur or oxygen as additional hetereo atoms;A is a saturated or unsaturated hydrocarbon chain of one to five carbon atoms, unsubstituted or substituted by lower alkyl; lower alkoxy; lower alkylthio; hydroxy; halogen; lower alkyl substituted by halogen, amino, loweralkoxycarbonyl, carboxy, lower-alkoxy, loweralkylthio, loweracyloxy or hydroxy; loweralkylamino; carboxy; nitro; cyano; carbonyl; imino; or by substituted or unsubstituted phenyl, phenylthio, phenylamino or phenoxy; andR.

Abstract: 2,4-diamino-6-(2,5-dichlorophenyl)-1,3,5-triazine and pharmaceutically acceptable acid addition salts thereof in finely pulverized form so that the average particle diameter is 20 microns or less have been found to be particularly useful for the treatment of peptic ulcers. When administered to humans in need thereof, 1 to 4 mg per day has been found effective.

Abstract: 1-phenoxy-3-(4-phenylpiperazino)-2-propanol derivatives of the formula (I): ##STR1## and pharmaceutically acceptable salts thereof wherein R.sup.1 is hydrogen, halo or lower alkyl; R.sup.2 is pyrrolidino, piperidino, morpholino or perhydroazepino unsubstituted or substituted by carbonyl at the alpha-position; R.sup.3 is hydrogen, lower alkyl or lower alkoxycarbonyl; and R.sup.4 is hydrogen, lower alkyl unsubstituted or alpha-substituted by lower alkoxy, lower alkoxy, halo or lower alkanoyl are useful for their alpha and beta-adrenergic blocking action and their hypotensive activity in humans and animals.

Abstract: 3-methylflavone derivatives which are useful in the treatment of allergies, asthma and inflammation.

Abstract: This is a process and apparatus for the preparation of fasciated spun yarns, which includes feeding separate single fibers formed by opening and drafting a continuous staple fiber bundle into a rotor (20), collecting and holding the single fibers on a fiber-collecting portion of the rotor (20) and taking out the collected fibers through a center piece (26) by delivery rollers (33) while strongly false-twisting the collected fibers in the same direction as that of true twists given by the rotor (20) into a twisted yarn by a false-twisting apparatus arranged between the rotor (20) and the delivery rollers (33), wherein the separated single fibers are supplied to a travelling plane for the twisted yarn between the fiber-collecting portion of the rotor (20) and the center piece (26) to entangle some of the single fibers with the twisted yarn in the strongly false-twisted state, and the entangled single fibers are entwined around the periphery of the twisted yarn by subsequent release of the false twists of the tw

Abstract: A variable venturi type carburetor comprising a carburetor body having an intake passage in which is disposed a slide valve slidably supported for travel across the intake passage to function as a variable venturi. A butterfly throttle valve is pivotably supported by the body in the intake passage downstream of the slide valve. A low-speed fuel passageway and a main fuel passageway open into the intake passage proximate the butterfly throttle valve and directly below the slide valve respectively. The slide valve and butterfly throttle valve are interconnected by a linkage for interlocked operation over a range from their fully closed positions to their fully opened positions with the degree of opening of the slide valve being greater than that of the butterfly valve by a predetermined magnitude at least for low opening degrees thereof. An external force is applied to one of the valves to operate that valve and the other of the valves conjointly therewith.

Abstract: Compounds of the formula (I): ##STR1## and pharmaceutically acceptable salts thereof wherein R.sup.1 is hydrogen, alkyl of 1 to 10 carbon atoms or acyl of 1 to 6 carbon atoms; R.sup.2 is hydrogen or halo; R.sup.3 is hydrogen, alkyl of 1 to 6 carbon atoms or acyl of 1 to 6 carbon atoms; R.sup.4 is hydrogen or alkyl of 1 to 6 carbon atoms; R.sup.5 is hydrogen or acyl of 1 to 6 carbon atoms; X is CONH.sub.2, hydroxyalkyl of 1 to 4 carbon atoms or COOR.sup.6 wherein R.sup.6 is hydrogen or alkyl of 1 to 4 carbon atoms; and Y is CONH.sub.2, hydroxyalkyl of 1 to 4 carbon atoms or COOR.sup.7 wherein R.sup.7 is hydrogen, alkyl of 1 to 10 carbon atoms or benzyl are useful for inhibiting the activity of amino-peptidase B, exhibit immunomodulating action against living organisms and exhibit anti-inflammatory activity.

Abstract: N-aralkylmoranoline and N-aralkenylmoranoline, and their pharmaceutical acceptable non-toxic acid addition salts thereof, pharmaceutical compositions containing the same and methods of inhibiting the increase in blood sugar level by administration of the same.

Abstract: 2,4-Diamino-6-(2,5-dichlorophenyl)-1,3,5-triazine and pharmaceutically acceptable acid addition salts thereof in finely pulverized form so that the average particle diameter is 20 microns or less have been found to be particularly useful for the treatment of peptic ulcers.

Abstract: 4-Hydroxy-2-quinolone derivatives are useful for their anti-inflammatory, anti-allergenic, antitussive and expectorant activity. Pharmaceutical compositions containing said compounds and pharmaceutically acceptable salts thereof and methods of treating humans and animals are described herein.

Abstract: A method of prevention and/or treatment of disorders of the liver, kidney, colon or rectum in mammals including humans which comprises administering to the patient a therapeutically effective amount of 2,4-diamino-6-(2',5-dichlorophenyl)-s-triazine maleate sufficient to prevent and/or overcome said disorders, and pharmaceutical compositions therefor.

Abstract: Glutamine derivatives and non-toxic salts thereof have been found to have immunomodulating activities.

Abstract: 4-(3-Aryloxy-2-hydroxypropyl)piperazines bearing a carbamyl group in the 1-position are .beta.-adrenergic blockers. A typical example is 1-carbamyl-4-{3-[2-allyl-3-(2-carbethoxyaminoethyl)phenoxy]-2-hydroxypropy l}piperazine.

Abstract: Compounds useful in the treatment of rheumatism or allergic nephritis which have the formula ##STR1## wherein X is halogen, hydroxy, lower alkyl, lower alkenyl, lower alkoxy, nitro or amino;Y is hydrogen, halogen, hydroxy, lower alkyl, lower alkenyl, lower alkoxy, nitro or amino; andZ is mono-(lower alkyl)amino, di-(lower alkyl)amino, piperidino, piperazino, pyrrolidino, or morpholino.

Abstract: Oxygenated sterylglycoside derivatives of the formula (I) wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are the same or different and each is hydrogen or lower alkanoyl, Y is ##STR1## and R.sub.5 is 4-methylpentyl, 3-ethyl-4-methylpentyl or 3-ethyl-4-methyl-1-pentenyl are useful for their hemostatic and capillary stabilizing effects.

Abstract: A vehicle with at least one front wheel and two rear wheels comprises a rear cushion unit for use in damping repelling forces from the ground surface and other vibratory forces developed by chain driving and the like. The upper end of the rear cushion unit is supported at a position axially rearward of a main frame member of a frame structure, while the lower end thereof is supported at a position forward of a rear axle bearing member. On each side of the rear axle bearing member there is mounted either a sprocket wheel or a braking device.

Abstract: Bisglucosyl moranoline of the formula (I) ##STR1## is useful in inhibiting increase of blood sugar in sugar-loaded animals and humans, and particularly for treatment of diabetes mellitus.

Abstract: Moranoline, or 2-hydroxymethyl-3,4,5-trihydroxy piperidine, is prepared by directly reducing an actinomycetes culture solution containing nojirimycin, followed by isolation, as for example, through the utilization of an ion exchange resin. The corresponding N-methyl derivative can be obtained through the addition of formaldehyde to the culture solution prior to the reduction.