Patents by Inventor Hiroshi Takagi

Hiroshi Takagi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080076163
    Abstract: L-cysteine is produced by culturing an Escherichia bacterium having L-cysteine producing ability and containing a gene encoding an O-acetylserine sulphydrylase B or MalY regulatory protein that is modified so that cysteine desulfhydrase activity is reduced or eliminated. The bacterium is cultured in a medium to produce and cause accumulation of L-cysteine in the medium, and collecting L-cysteine from the medium.
    Type: Application
    Filed: March 3, 2005
    Publication date: March 27, 2008
    Inventors: Hiroshi Takagi, Shigeru Nakamori, Masaru Wada, Hirotada Mori
  • Patent number: 7332259
    Abstract: Disclosed is a process for manufacturing an aluminum support for a light sensitive planographic printing plate material, the process comprising the steps of surface-roughening an aluminum plate, anodizing the surface-roughened aluminum plate, surface treating the anodized aluminum plate with an aqueous polyvinyl phosphonic acid solution, and drying the resulting plate at from 150 to 230° C. to obtain the aluminum support.
    Type: Grant
    Filed: April 8, 2005
    Date of Patent: February 19, 2008
    Assignee: Konica Minolta Medical & Graphic, Inc.
    Inventor: Hiroshi Takagi
  • Patent number: 7329726
    Abstract: A peptide according to the present invention is selected from the group consisting of: (a) a peptide having the amino acid sequence represented by SEQ ID NO: 1; (b) a peptide having a modified amino acid sequence of the amino acid sequence described in (a) above, in which one or more amino acid residues are deleted, substituted, inserted or added, and having cell death-preventing activity and/or cell growth-promoting activity; and (c) a peptide which has an amino acid sequence having at least 80% homology with the peptide consisting of the amino acid sequence described in (a) above and has cell death-preventing activity and/or cell growth-promoting activity. The peptide has cell death-preventing activity and/or cell growth-promoting activity, is highly safe, and can be produced without difficulty. The peptide is useful as a culture supplement or as an effective component for a cell culture medium.
    Type: Grant
    Filed: December 13, 2004
    Date of Patent: February 12, 2008
    Assignee: Seiren Kabushiki Kaisha
    Inventors: Shigeru Nakamori, Hiroshi Takagi, Masakazu Takahashi, Kazuhisa Tsujimoto, Hideyuki Yamada
  • Patent number: 7314745
    Abstract: An objective of the present invention is to provide a new protein derived from the silkworm middle silk gland and a DNA encoding said protein. The present invention relates to a protein of the following (a) or (b): (a) a protein comprising the amino acid sequence represented by SEQ ID NO: 1; (b) a protein comprising a modified amino acid sequence of the amino acid sequence described in (a) above, in which one or more amino acid residues are deleted, substituted, inserted or added, and having protease activity.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: January 1, 2008
    Assignee: Seiren Kabushiki Kaisha
    Inventors: Shigeru Nakamori, Hiroshi Takagi, Masakazu Takahashi, Kazuhisa Tsujimoto, Hideyuki Yamada
  • Patent number: 7312058
    Abstract: O-acetylserine, L-cysteine and sulphurous compounds derived therefrom may be produced using a bacterium belonging to the genus Escherichia which harbors a mutant feedback-resistant serine acetyltransferases in which the amino acid sequence corresponding to positions from 89 to 96 in a wild-type serine acetyltransferase is replaced with any one of the amino acid sequences shown in SEQ ID NOS: 4 to 9, and feedback inhibition by L-cysteine in the bacterium is desensitized.
    Type: Grant
    Filed: July 16, 2004
    Date of Patent: December 25, 2007
    Assignee: Ajinomoto Co., Ltd.
    Inventors: Tatsuki Kashiwagi, Yuko Kai, Kohki Ishikawa, Ei-ichiro Suzuki, Hiroshi Takagi, Mikhail Kharisovich Ziyatdinov, Ekaterina Igorevna Redkina, Mikhail Markovich Gusyatiner
  • Publication number: 20070203075
    Abstract: An enzyme capable of reducing the antibiotic activity (i.e., toxicity) of streptothricin with respect to eukaryotic cells without sacrificing antibiotic activity with respect to prokaryotic cells is provided along with a streptothricin derivative having reduced toxicity with respect to eukaryotic cells while retaining antibiotic activity with respect to prokaryotic cells, and a manufacturing method thereof. By opening the lactam ring of streptothricin, a protein having the amino acid sequence according to SEQ ID NO: 2, 4, 6, 8, 10, 12, 14 or 16 of the invention can reduce the antibiotic activity of streptothricin D with respect to eukaryotic cells without sacrificing antibiotic activity with respect to prokaryotic cells.
    Type: Application
    Filed: February 26, 2007
    Publication date: August 30, 2007
    Inventors: Hiroshi Takagi, Yoshimitsu Hamano
  • Patent number: 7192689
    Abstract: Disclosed is a process for manufacturing an aluminum support for a planographic printing plate material, the process comprising the steps of electrolytically surface-roughening an aluminum plate in an electrolytic solution, employing a sinewave alternating current; and anodizing the surface-roughened aluminum plate, the electrolytically surface-roughening step comprising a first stage of electrolytically surface-roughening the aluminum plate in a first electrolytic solution containing hydrochloric acid as a main component at a current density of D1 for t1 at a quantity of electricity of Q1 and a second stage of electrolytically surface-roughening the aluminum plate in a second electrolytic solution containing hydrochloric acid as a main component at a current density of D2 for t2 at a quantity of electricity of Q2.
    Type: Grant
    Filed: December 16, 2004
    Date of Patent: March 20, 2007
    Assignee: Konica Minolta Medical & Graphic, Inc.
    Inventor: Hiroshi Takagi
  • Publication number: 20070053555
    Abstract: A medical image display method of this invention includes an organ display step for displaying an image of a predetermined organ including a desired blood vessel in a medical image on a display unit; a blood vessel selection step for selecting the desired blood vessel from the image of the predetermined organ displayed by the organ display step and designating a specific position of the desired blood vessel; and an image display step for displaying a pseudo image in a pseudo imaging mode as if a contrast, agent were made to flow through the blood vessel selected in the blood vessel selection step. The pseudo image of the flow of the contrast agent in the blood vessel assists doctor in conducting diagnoses and therapies.
    Type: Application
    Filed: September 9, 2004
    Publication date: March 8, 2007
    Inventors: Masao Ooi, Hiroshi Takagi, Yoshihiro Goto
  • Patent number: 7157209
    Abstract: A process for manufacturing an aluminum support for a planographic printing plate material, the process containing the steps of: (a) electrolytically surface-roughening an aluminum plate in an electrolyte solution containing hydrochloric acid as a main component; and (b) anodizing the surface-roughened aluminum plate, wherein the step (a) contains: (i) a first stage which surface-roughens the aluminum plate employing a sine-wave alternating current; and (ii) a second stage which surface-roughens the aluminum plate employing a controlled sine-wave alternating current using a thyristor so that a current flow starts at a phase angle of 60 to 120 degree of an alternating current cycle.
    Type: Grant
    Filed: February 9, 2005
    Date of Patent: January 2, 2007
    Assignee: Konica Minolta Medical & Graphic, Inc.
    Inventor: Hiroshi Takagi
  • Patent number: 7148047
    Abstract: L-cysteine is produced by culturing a coryneform bacterium in which intracellular serine acetyltransferase activity is increased by transformation with a gene coding for serine acetyltransferase, such modification of an expression control sequence of a gene coding for serine acetyltransferase that expression of the gene in a cell should be enhanced and for forth, preferably in which L-cysteine decomposition system is further suppressed, in a medium to produce and accumulate L-cysteine in culture and collecting the L-cysteine from the culture.
    Type: Grant
    Filed: February 1, 2002
    Date of Patent: December 12, 2006
    Assignee: Ajinomoto Co., Inc.
    Inventors: Hiroshi Takagi, Masaru Wada, Shigeru Nakamori
  • Publication number: 20060267159
    Abstract: In an electronic component, an active chip element and a passive chip element are respectively enclosed within first and second resin layers, which are separately disposed on upper and lower surfaces of a core substrate, respectively. The first resin layer includes a shielding metal film disposed on an upper surface thereof and a first via-hole conductor which connects the shielding metal film with a circuit pattern provided on the core substrate. The second resin layer includes an external-terminal electrode disposed on a lower surface thereof and a second via-hole conductor which connects the external-terminal electrode with a circuit pattern provided on the core substrate.
    Type: Application
    Filed: August 2, 2006
    Publication date: November 30, 2006
    Applicant: MURATA MANUFACTURING CO., LTD.
    Inventors: Yuki YAMAMOTO, Jun HARADA, Hiroshi TAKAGI, Katsuro HIRAYAMA
  • Publication number: 20060037506
    Abstract: An object of the invention is to provide a planographic printing plate material exhibiting excellent dot reproduction and printing durability and a support for the planographic printing plate material. Disclosed is a support for a planographic printing plate material having a surface roughened via electrolytic surface-roughening treatment and anodization treatment conducted to one surface of an aluminum plate, wherein a) average surface roughness (Ra) of the roughened surface is 0.30-0.55 ?m, and b) the roughened surface possesses a surface profile in which a ratio of Xa/Xb is 0.40-0.70, where Xa is the width expanding to the shallow region side and Xb is the width expanding to the deep region side at the position reaching peak depth in amplitude frequency.
    Type: Application
    Filed: July 22, 2005
    Publication date: February 23, 2006
    Applicant: KONICA MINOLTA MEDICAL & GRAPHIC, INC.
    Inventor: Hiroshi Takagi
  • Patent number: 6969376
    Abstract: The mechanism includes: an urging means for urging an inner needle (12) to the side opposite to an outer needle (11) with respect to the axial direction of a holder sleeve (1) for holding the inner needle (12); an actuator (6) which is positioned between the urging means (8) and inner needle (12), moves together with the inner needle (12) and has a puncture position retainer for keeping the inner needle (12) and outer needle (11) ready for puncture and an inner needle retraction actuating portion for allowing for the retraction actuation of the inner needle (12); and a slit (2) for assuring the path of movement of the actuator (6). The puncture position retainer has a puncture position engagement portion whereby the actuator (6) is engaged with the holder sleeve (1) at a position on the outer needle side (11).
    Type: Grant
    Filed: July 12, 2001
    Date of Patent: November 29, 2005
    Assignee: Mitsubishi Pencil Kabushiki Kaisha
    Inventors: Hiroshi Takagi, Kentaro Takemae
  • Publication number: 20050233250
    Abstract: Disclosed is a process for manufacturing an aluminum support for a light sensitive planographic printing plate material, the process comprising the steps of surface-roughening an aluminum plate, anodizing the surface-roughened aluminum plate, surface treating the anodized aluminum plate with an aqueous polyvinyl phosphonic acid solution, and drying the resulting plate at from 150 to 230 ° C. to obtain the aluminum support.
    Type: Application
    Filed: April 8, 2005
    Publication date: October 20, 2005
    Applicant: KONICA MINOLTA MEDICAL & GRAPHIC, INC.
    Inventor: Hiroshi Takagi
  • Publication number: 20050221453
    Abstract: L-Cysteine is produced by culturing a microorganism having an ability to produce L-cysteine and modified so that expression of emrAB, emrKY, yojIH, acrEF, bcr, or cusA gene should be enhanced in a medium to produce and accumulate L-cysteine in the medium and collecting the L-cysteine from the medium. Genes coding for novel L-cysteine-excreting proteins are identified, and utilized for breeding of L-cysteine-producing microorganism to provide a novel method of producing L-cysteine.
    Type: Application
    Filed: October 5, 2004
    Publication date: October 6, 2005
    Applicant: AJINOMOTO CO., INC
    Inventors: Hiroshi Takagi, Shigeru Nakamori, Akihito Yamaguchi, Kunihiko Nishino
  • Patent number: 6946268
    Abstract: L-Cysteine is produced by culturing a bacterium belonging to the genus Escherichia having an L-cysteine producing ability and modified so that cystathionine-?-lyase activity or cystathionine-?-lyase activity and tryptophanase activity should be reduced or eliminated in a medium to produce and accumulate L-cysteine in the medium and collecting the L-cysteine from the medium.
    Type: Grant
    Filed: September 26, 2002
    Date of Patent: September 20, 2005
    Assignee: Ajinomoto Co., Inc.
    Inventors: Hiroshi Takagi, Masaru Wada, Shigeru Nakamori
  • Publication number: 20050199505
    Abstract: A process for manufacturing an aluminum support for a planographic printing plate material, the process containing the steps of: (a) electrolytically surface-roughening an aluminum plate in an electrolyte solution containing hydrochloric acid as a main component; and (b) anodizing the surface-roughened aluminum plate, wherein the step (a) contains: (i) a first stage which surface-roughens the aluminum plate employing a sine-wave alternating current; and (ii) a second stage which surface-roughens the aluminum plate employing a controlled sine-wave alternating current using a thyristor so that a current flow starts at a phase angle of 60 to 120 degree of an alternating current cycle.
    Type: Application
    Filed: February 9, 2005
    Publication date: September 15, 2005
    Applicant: KONICA MINOLTA MEDICAL & GRAPHIC, INC.
    Inventor: Hiroshi Takagi
  • Publication number: 20050196861
    Abstract: A peptide according to the present invention is selected from the group consisting of: (a) a peptide having the amino acid sequence represented by SEQ ID NO: 1; (b) a peptide having a modified amino acid sequence of the amino acid sequence described in (a) above, in which one or more amino acid residues are deleted, substituted, inserted or added, and having cell death-preventing activity and/or cell growth-promoting activity; and (c) a peptide which has an amino acid sequence having at least 80% homology with the peptide consisting of the amino acid sequence described in (a) above and has cell death-preventing activity and/or cell growth-promoting activity. The peptide has cell death-preventing activity and/or cell growth-promoting activity, is highly safe, and can be produced without difficulty. The peptide is useful as a culture supplement or as an effective component for a cell culture medium.
    Type: Application
    Filed: December 13, 2004
    Publication date: September 8, 2005
    Inventors: Shigeru Nakamori, Hiroshi Takagi, Masakazu Takahashi, Kazuhisa Tsujimoto, Hideyuki Yamada
  • Publication number: 20050163467
    Abstract: While viewing and listening to AV data, other AV data is converted and transferred to a reproducing terminal. A recorder has two decoding parts as a decoding unit of AV data on a recording medium. AV data which was decoded in one of the decoding parts is supplied to a monitor device. When there is a transfer request for AV data, in accordance with a schedule which is formulated based on a transfer request list and a programmed picture recording list, AV data in the transfer request list is decoded in the other one of the decoding parts, encoded in an encoding part, converted into new AV data, and recorded in the recording medium. When a connection to the reproducing terminal is detected, the new AV data on the recording medium is transferred to the reproducing terminal. Since it has two decoding parts, it is possible to convert other AV data into new AV data while viewing and listening to AV data on the monitor device.
    Type: Application
    Filed: December 13, 2004
    Publication date: July 28, 2005
    Applicant: Sony Corporation
    Inventors: Hiroshi Takagi, Junji Oiwa
  • Publication number: 20050153242
    Abstract: Disclosed is a process for manufacturing an aluminum support for a planographic printing plate material, the process-comprising the steps of electrolytically surface-roughening an aluminum plate in an electrolytic solution, employing a sinewave alternating current; and anodizing the surface-roughened aluminum plate, the electrolytically surface-roughening step comprising a first stage of electrolytically surface-roughening the aluminum plate in a first electrolytic solution containing hydrochloric acid as a main component at a current density of D1 for t1 at a quantity of electricity of Q1 and a second stage of electrolytically surface-roughening the aluminum plate in a second electrolytic solution containing hydrochloric acid as a main component at a current density of D2 for t2 at a quantity of electricity of Q2.
    Type: Application
    Filed: December 16, 2004
    Publication date: July 14, 2005
    Applicant: KONICA MINOLTA MEDICAL & GRAPHIC. INC.
    Inventor: Hiroshi Takagi