Patents by Inventor Hiroshi Tokuda

Hiroshi Tokuda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5108084
    Abstract: A sheet feeding device for automatically feeding sheet paper from a cassette or feeding one sheet of paper at a time as the sheets are inserted into an insertion guide. The paper is fed in the automatic feed mode by bringing the stacked paper and a rotating sheet feeding roller into contact with one another. When the manual feed mode is selected, the stacked paper and the rotating roller are separated. A sheet of paper placed in the insertion guide is fed to a contact point between the sheet feeding rollers, now rotating counter to the rotational direction during automatic sheet feeding, and an opposing pressure rollers.
    Type: Grant
    Filed: May 13, 1991
    Date of Patent: April 28, 1992
    Assignee: Brother Kogyo Kabushiki Kaisha
    Inventors: Shigeo Ishikawa, Hiroshi Tokuda, Seijiro Kadowaki, Fumio Morita, Hirokazu Kishimoto
  • Patent number: 5106072
    Abstract: A sheet feeding device includes a member for depressing a pair of rollers to feed the top sheet off a stack of papers in a case. The depressing member is only operated when the case is positioned in an associated device. The spacing between the feed rollers is variable and controlled in accordance with the width of the stacked sheets.
    Type: Grant
    Filed: January 17, 1991
    Date of Patent: April 21, 1992
    Assignee: Brother Kogyo Kabushiki Kaisha
    Inventors: Toshiaki Sugiura, Shigeo Ishikawa, Hiroshi Tokuda, Hikaru Kaga
  • Patent number: 5052673
    Abstract: A sheet feed device for feeding sheets from a stack to a machine, such as a copier, is provided with rollers for feeding the top sheet of the stack to the entrance of the machine. When a sheet is being fed through the machine, the presence of the sheet is sensed and used to generate a signal to disengage the rollers from the stack to thereby ensure precise feeding of the sheets.
    Type: Grant
    Filed: September 6, 1989
    Date of Patent: October 1, 1991
    Assignee: Brother Kogyo Kabushiki Kaisha
    Inventors: Hiroshi Tokuda, Shigeo Ishikawa, Toshiaki Sugiura, Hikaru Kaga
  • Patent number: 4908632
    Abstract: A thermal printing apparatus includes a carriage body on which a thermal ribbon cassette is detachably mounted, a driving gear rotated in accordance with the movement of the carriage body, a spool shaft rotatably mounted on the carriage body for rotating a ribbon spool of a ribbon cassette, and a rotation transmitting mechanism adapted to interlink or interrupt between the driving gear and the spool shaft when a ribbon cassette is mounted on or removed from the carriage body, respectively. The thermal printing apparatus further includes a shaft operable to detect if a ribbon cassette is mounted, and the rotation transmitting mechanism includes an engaging member engageable with a disc portion secured to the shaft for holding the rotation transmitting mechanism in a state where the interlinking between the driving gear and the spool shaft is interrupted.
    Type: Grant
    Filed: February 7, 1989
    Date of Patent: March 13, 1990
    Assignee: Brother Kogyo Kabushiki Kaisha
    Inventors: Shigeo Ishikawa, Hiroshi Tokuda, Akira Ninomiya
  • Patent number: 4532137
    Abstract: Disclosed are 2-thiazol derivatives having the general formula ##STR1## where R.sub.1 and R.sub.2 independently represent lower alkyl radicals having 1 to 4 carbon atoms and X represents a lower alkyl radical, a lower alkoxy radical, a lower alkoxycarbonyl radical, a halogenoalkoxy radical, a radical of the formula ##STR2## or a radical of the formula ##STR3## Also disclosed are a process for preparing the derivatives and pharmaceutical compositions having immunomodulatory activity which comprise the derivatives as the active ingredient.
    Type: Grant
    Filed: January 6, 1984
    Date of Patent: July 30, 1985
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Isao Sakano, Tatsuro Yokoyama, Seitaro Kajiya, Yutaka Okazaki, Hiroshi Tokuda, Hiroshi Kawazura, Mikio Kumakura, Takuo Nakano, Akira Awaya
  • Patent number: 4524147
    Abstract: Disclosed are uracil derivatives having the general formula ##STR1## where R represents a hydrogen atom or an alkyl radical having 1 to 4 carbon atoms. Also disclosed are a process for preparing these compounds and pharmaceutical compositions having immunomodulatory activity which comprise these compounds as the active ingredient.
    Type: Grant
    Filed: November 16, 1982
    Date of Patent: June 18, 1985
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Isao Sakano, Tatsuro Yokoyama, Seitaro Kajiya, Yutaka Okazaki, Hiroshi Tokuda, Hiroshi Kawazura, Mikio Kumakura, Akira Awaya
  • Patent number: 4511574
    Abstract: The present invention provides new chemical compounds, N-(4-phenyl-2-thiazolyl)carbamate derivatives, a process for preparing the same and pharmaceutical compositions containing the carbamate derivatives. More particularly, the present invention provides N-(4-phenyl-2-thiazolyl)carbamate derivatives which have immuno-modulating activity and are thus effective against immunodiseases such as chronic rheumatoid arthritis and also useful against viral diseases or for the immunotherapy of cancers with low toxicity.
    Type: Grant
    Filed: September 8, 1982
    Date of Patent: April 16, 1985
    Assignee: Mitsui Toatsu Kagaku Kabushiki Kaisha
    Inventors: Isao Sakano, Tatsuro Yokoyama, Seitaro Kajiya, Yutaka Okazaki, Hiroshi Tokuda, Hiroshi Kawazura, Mikio Kumakura, Takuo Nakano, Akira Awaya
  • Patent number: 4501750
    Abstract: The present invention provides new thiazole compounds possessing immuno-modulating activity, i.e. thiazole compounds of the general formula (1): ##STR1## wherein R.sub.1 stands for a hydrogen or halogen atom or a lower alkyl, lower alkoxy, substituted or unsubstituted phenoxy, nitro or cyano group, R.sub.2 for a hydrogen atom or a lower alkyl or lower alkylthio group, and R for an .alpha.-halogenoalkyl group or the grouping: ##STR2## a process for preparing same and pharmaceutical compositions containing the thiazole compounds.
    Type: Grant
    Filed: September 13, 1982
    Date of Patent: February 26, 1985
    Assignee: Mitsui Toatsu Kaguku Kabushiki Kaisha
    Inventors: Isao Sakano, Tatsuro Yokoyama, Seitaro Kajiya, Yutaka Okazaki, Hiroshi Tokuda, Hiroshi Kawazura, Mikio Kumakura, Takuo Nakano, Akira Awaya
  • Patent number: 4490393
    Abstract: The present invention provides thiazolyl derivatives as new chemical substance represented by the general formula: ##STR1## wherein R.sup.1 stands for a lower alkyl group or a substituted or unsubstituted phenyl group, R.sup.2 for a hydrogen atom, a lower alkyl, lower alkoxy or lower alkylthio group, and R.sup.3 for a pyridyl or iso-oxazolyl group or a grouping of the general formula: ##STR2## processes for preparing same and pharmaceutical compositions containing the thiazolyl derivatives. More particularly, the present invention provides new thiazolyl derivatives which possess immuno-modulating activity and are thus therapeutically effective against immunodiseases such as chronic rheumatoid arthritis and also useful against viral diseases or for the immunotherapy of cancers and possess properties desirous as medicines with a slight toxicity, processes for preparing same and pharmaceutical compositions containing the new substance.
    Type: Grant
    Filed: September 17, 1982
    Date of Patent: December 25, 1984
    Assignee: Mitsui Toatsu Kagaki Kabushiki Kaisha
    Inventors: Isao Sakano, Tatsuro Yokoyama, Seitaro Kajiya, Tamotsu Minami, Yutaka Okazaki, Hiroshi Tokuda, Hiroshi Kawazura, Mikio Kumakura, Takuo Nakano, Akira Awaya
  • Patent number: 4476128
    Abstract: The present invention relates to a piperazine compound represented by the following general formula (I): ##STR1## wherein X stands for a hydrogen atom or a phenyl group, R.sup.1 stands for a hydrogen atom or an alkyl group, and R.sup.2 stands for a hydrogen atom or an alkyl group.These compounds are valuable as immunopotentiators, such as for the treatment of chronic rheumatoid arthritis and other diseases accompanied by reduction or abnormal change of the immune function.
    Type: Grant
    Filed: January 13, 1983
    Date of Patent: October 9, 1984
    Assignee: Mitsuitoatsu Chemicals, Inc.
    Inventors: Isao Sakano, Shiyoichiro Miyahara, Yoshitsugu Yamada, Yutaka Okazaki, Hiroshi Tokuda, Akira Awaya, Takuo Nakano
  • Patent number: 4473577
    Abstract: Disclosed are 2-thiazol derivatives having the general formula ##STR1## where R.sub.1 and R.sub.2 independently represent lower alkyl radicals having 1 to 4 carbon atoms and X represents a lower alkyl radical, a lower alkoxy radical, a lower alkoxycarbonyl radical, a halogenoalkoxy radical, a radical of the formula ##STR2## or a radical of the formula ##STR3## Also disclosed are a process for preparing the derivatives and pharmaceutical compositions having immunomodulatory activity which comprise the derivatives as the active ingredient.
    Type: Grant
    Filed: October 22, 1982
    Date of Patent: September 25, 1984
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Isao Sakano, Tatsuro Yokoyama, Kajiya Seitaro, Yutaka Okazaki, Hiroshi Tokuda, Hiroshi Kawazura, Mikio Kumakura, Takuo Nakano, Akira Awaya
  • Patent number: 4446133
    Abstract: The present invention relates to a novel piperazine compound represented by the following general formula (I): ##STR1## wherein X stands for a hydrogen or halogen atom, an alkoxy, carboxy or alkoxycarbonyl group or a group R.sup.3 CO-- in which R.sup.3 stands for an alkyl group having 1 to 4 carbon atoms, R.sup.1 stands for a hydrogen atom or an alkyl group, and R.sup.2 stands for a hydrogen atom or an alkyl group.These compounds are valuable as immunopotentiators, such as for the treatment of chronic rheumatoid arthritis and other diseases accompanied by reduction or abnormal change of the immune function.
    Type: Grant
    Filed: February 13, 1981
    Date of Patent: May 1, 1984
    Assignee: Misuitoatsu Chemicals, Inc.
    Inventors: Yutaka Okazaki, Hiroshi Tokuda, Shiyoichiro Miyahara, Yoshitsugu Yamada
  • Patent number: 4420481
    Abstract: The present invention relates to a novel piperazine compound represented by the following general formula (I): ##STR1## wherein R stands for an alkyl or phenyl group, and n is a number of 4 or 5.These compounds are valuable as an immunopotentiators, such as for the treatment of chronic rheumatoid arthritis and other diseases accompanied by reduction or abnormal change of immune function.
    Type: Grant
    Filed: February 19, 1981
    Date of Patent: December 13, 1983
    Assignee: Mitsuitoatsu Chemicals Inc.
    Inventors: Yutaka Okazaki, Hiroshi Tokuda, Shiyoichiro Miyahara, Yoshitsugu Yamada