Patents by Inventor Hirosuke Okada

Hirosuke Okada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant DNA, transformant containing said DNA, and process for preparing heat-stable glucose dehydrogenase by use of said transformant
    Patent number: 5114853
    Abstract: A recombinant DNA replicable and expressible in Escherichia coli is disclosed which encodes glucose dehydrogenase originating from Bacillus megaterium. A DNA sequence encoding the glucose dehydrogenase is incorporated into an E. coli vector and then used to transform an E. coli host. Also disclosed are transformants and recombinant DNA incorporating thermostable glucose dehydrogenase, wherein at least one amino acid in glucose dehydrogenase at positions 96, 252, and 253 is replaced by a thermostability-conferring amino acid.
    Type: Grant
    Filed: September 22, 1989
    Date of Patent: May 19, 1992
    Assignee: Amano Pharmaceutical Co., Ltd.
    Inventors: Yasutaka Makino, Seiji Negoro, Itaru Urabe, Hirosuke Okada
  • Gene coding for thermostable beta-galactosidase, bacillus subtilis having the gene, enzyme coded by the gene and a process for the production thereof
    Patent number: 4861718
    Abstract: A novel gene coding for thermostable .beta.-galactosidase, novel recombinant DNA in which a DNA fragment containing the above gene is inserted, novel Bacillus subtilis in which the above recombinant DNA is introduced, and novel thermostable .beta.-galactosidase obtained by cultivating the above Bacillus subtilis.
    Type: Grant
    Filed: September 27, 1985
    Date of Patent: August 29, 1989
    Assignee: Wakamoto Pharmaceutical Co., Ltd.
    Inventors: Haruhisa Hirata, Hirosuke Okada, Seiji Negoro