Patents by Inventor Hiroto Bando
Hiroto Bando has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9427434Abstract: The present invention provides a preparation containing pioglitazone or a salt thereof as an active ingredient, which shows high bioavailability of pioglitazone and less interindividual variation in blood drug concentration, as well as a preparation with suppressed color change during preservation. The preparation contains a core containing a pharmaceutically acceptable organic acid with water solubility at 20° C. of not less than 10 mg/mL and pKa1 (a negative common logarithm of the first acid dissociation constant Ka1) at 25° C. of not more than 5, and a coating layer containing pioglitazone or a salt thereof. The coating layer may further contain mannitol or trehalose.Type: GrantFiled: July 10, 2008Date of Patent: August 30, 2016Assignee: Takeda Pharmaceutical Company LimitedInventors: Hiroto Bando, Yoshihiro Omachi, Kenichiro Kiyoshima
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Publication number: 20160128945Abstract: A controlled release preparation wherein the release of active ingredient is controlled, which releases an active ingredient for an extended period of time by staying or slowly migrating in the gastrointestinal tract, is provided by means such as capsulating a tablet, granule or fine granule wherein the release of active ingredient is controlled and a gel-forming polymer. Said tablet, granule or fine granule has a release-controlled coating-layer formed on a core particle containing an active ingredient.Type: ApplicationFiled: December 28, 2015Publication date: May 12, 2016Inventors: Yohko AKIYAMA, Takashi KURASAWA, Hiroto BANDO, Naoki NAGAHARA
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Patent number: 8784885Abstract: A controlled release preparation wherein the release of active ingredient is controlled, which releases an active ingredient for an extended period of time by staying or slowly migrating in the gastrointestinal tract, is provided by means such as capsulating a tablet, granule or fine granule wherein the release of active ingredient is controlled and a gel-forming polymer. Said tablet, granule or fine granule has a release-controlled coating-layer formed on a core particle containing an active ingredient.Type: GrantFiled: July 19, 2010Date of Patent: July 22, 2014Assignee: Takeda Pharmaceutical Company LimitedInventors: Yohko Akiyama, Takashi Kurasawa, Hiroto Bando, Naoki Nagahara
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Publication number: 20140186448Abstract: A controlled release preparation wherein the release of active ingredient is controlled, which releases an active ingredient for an extended period of time by staying or slowly migrating in the gastrointestinal tract, is provided by means such as capsulating a tablet, granule or fine granule wherein the release of active ingredient is controlled and a gel-forming polymer. Said tablet, granule or fine granule has a release-controlled coating-layer formed on a core particle containing an active ingredient.Type: ApplicationFiled: March 6, 2014Publication date: July 3, 2014Inventors: Yohko AKIYAMA, Takashi KURASAWA, Hiroto BANDO, Naoki NAGAHARA
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Publication number: 20140186449Abstract: A controlled release preparation wherein the release of active ingredient is controlled, which releases an active ingredient for an extended period of time by staying or slowly migrating in the gastrointestinal tract, is provided by means such as capsulating a tablet, granule or fine granule wherein the release of active ingredient is controlled and a gel-forming polymer. Said tablet, granule or fine granule has a release-controlled coating-layer formed on a core particle containing an active ingredient.Type: ApplicationFiled: March 6, 2014Publication date: July 3, 2014Inventors: Yohko AKIYAMA, Takashi KURASAWA, Hiroto BANDO, Naoki NAGAHARA
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Patent number: 8722084Abstract: A controlled release preparation wherein the release of active ingredient is controlled, which releases an active ingredient for an extended period of time by staying or slowly migrating in the gastrointestinal tract, is provided by means such as capsulating a tablet, granule or fine granule wherein the release of active ingredient is controlled and a gel-forming polymer. Said tablet, granule or fine granule has a release-controlled coating-layer formed on a core particle containing an active ingredient.Type: GrantFiled: July 8, 2010Date of Patent: May 13, 2014Assignee: Takeda Pharmaceutical Company LimitedInventors: Yohko Akiyama, Takashi Kurasawa, Hiroto Bando, Naoki Nagahara
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Patent number: 8449911Abstract: Granule, fine particle or tablet of excellent leaching property, comprising a drug active ingredient in high content realized by forming a layer containing drug active ingredient on core particles through a combination of a method of dispersing and adhering an active ingredient while spraying or adding a binder with a method of spraying or adding a solution or suspension wherein an active ingredient and a binder are contained so as to effect adhesion. Further, there are provided a drug composition containing such a granule, fine particle or tablet and a process for producing the same.Type: GrantFiled: March 10, 2004Date of Patent: May 28, 2013Assignee: Takeda Pharmaceutical Company LimitedInventors: Shuji Yoneyama, Hiroto Bando
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Publication number: 20100285120Abstract: A controlled release preparation wherein the release of active ingredient is controlled, which releases an active ingredient for an extended period of time by staying or slowly migrating in the gastrointestinal tract, is provided by means such as capsulating a tablet, granule or fine granule wherein the release of active ingredient is controlled and a gel-forming polymer. Said tablet, granule or fine granule has a release-controlled coating-layer formed on a core particle containing an active ingredient.Type: ApplicationFiled: July 19, 2010Publication date: November 11, 2010Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITEDInventors: Yohko Akiyama, Takashi Kurasawa, Hiroto Bando, Naoki Nagahara
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Publication number: 20100278911Abstract: A controlled release preparation wherein the release of active ingredient is controlled, which releases an active ingredient for an extended period of time by staying or slowly migrating in the gastrointestinal tract, is provided by means such as capsulating a tablet, granule or fine granule wherein the release of active ingredient is controlled and a gel-forming polymer. Said tablet, granule or fine granule has a release-controlled coating-layer formed on a core particle containing an active ingredient.Type: ApplicationFiled: July 8, 2010Publication date: November 4, 2010Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITEDInventors: Yohko Akiyama, Takashi Kurasawa, Hiroto Bando, Naoki Nagahara
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Publication number: 20100272798Abstract: A controlled release preparation wherein the release of active ingredient is controlled, which releases an active ingredient for an extended period of time by staying or slowly migrating in the gastrointestinal tract, is provided by means such as capsulating a tablet, granule or fine granule wherein the release of active ingredient is controlled and a gel-forming polymer. Said tablet, granule or fine granule has a release-controlled coating-layer formed on a core particle containing an active ingredient.Type: ApplicationFiled: July 8, 2010Publication date: October 28, 2010Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITEDInventors: Yohko AKIYAMA, Takashi KURASAWA, Hiroto BANDO, Naoki NAGAHARA
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Patent number: 7790755Abstract: A controlled release preparation wherein the release of active ingredient is controlled, which releases an active ingredient for an extended period of time by staying or slowly migrating in the gastrointestinal tract, is provided by means such as capsulating a tablet, granule or fine granule wherein the release of active ingredient is controlled and a gel-forming polymer. Said tablet, granule or fine granule has a release-controlled coating-layer formed on a core particle containing an active ingredient.Type: GrantFiled: October 15, 2003Date of Patent: September 7, 2010Assignee: Takeda Pharmaceutical Company LimitedInventors: Yohko Akiyama, Takashi Kurasawa, Hiroto Bando, Naoki Nagahara
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Publication number: 20100166853Abstract: The present invention provides a preparation containing pioglitazone or a salt thereof as an active ingredient, which shows high bioavailability of pioglitazone and less interindividual variation in blood drug concentration, as well as a preparation with suppressed color change during preservation. The preparation contains a core containing a pharmaceutically acceptable organic acid with water solubility at 20° C. of not less than 10 mg/mL and pKa1 (a negative common logarithm of the first acid dissociation constant Ka1) at 25° C. of not more than 5, and a coating layer containing pioglitazone or a salt thereof. The coating layer may further contain mannitol or trehalose.Type: ApplicationFiled: July 10, 2008Publication date: July 1, 2010Inventors: Hiroto Bando, Yoshihiro Omachi, Kenichiro Kiyoshima
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Publication number: 20090175959Abstract: The present invention provides a controlled release solid preparation superior in the stability of an active ingredient, which can exhibit pharmacological effects steadily and rapidly after administration, and shows a sustained pharmacological effect for a prolonged period of time: a controlled release solid preparation containing (1) an antacid, (2) an immediate-release part containing a compound unstable to acid and a basic substance, and (3) a sustained-release part containing a compound unstable to acid and a pH-independent material in combination.Type: ApplicationFiled: December 28, 2006Publication date: July 9, 2009Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITEDInventors: Hiroto Bando, Takashi Kurasawa
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Publication number: 20090104264Abstract: The present invention provides a controlled release solid preparation superior in the stability of an active ingredient, which can exhibit pharmacological effects steadily and rapidly after administration, and shows a sustained pharmacological effect for a prolonged period of time: a controlled release solid preparation containing a combination of (1) an antacid, (2) an immediate-release part containing a compound unstable to acid and a basic substance, and (3) a sustained-release part containing a compound unstable to acid and a basic substance, and having a film that dissolves at pH 6.5 or above.Type: ApplicationFiled: December 28, 2006Publication date: April 23, 2009Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITEDInventors: Hiroto Bando, Takashi Kurasawa
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Publication number: 20060159760Abstract: Granule, fine particle or tablet of excellent leaching property, comprising a drug active ingredient in high content realized by forming a layer containing drug active ingredient on core particles through a combination of a method of dispersing and adhering an active ingredient while spraying or adding a binder with a method of spraying or adding a solution or suspension wherein an active ingredient and a binder are contained so as to effect adhesion. Further, there are provided a drug composition containing such a granule, fine particle or tablet and a process for producing the same.Type: ApplicationFiled: March 10, 2004Publication date: July 20, 2006Inventors: Shuji Yoneyama, Hiroto Bando
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Publication number: 20060013868Abstract: A controlled release preparation wherein the release of active ingredient is controlled, which releases an active ingredient for an extended period of time by staying or slowly migrating in the gastrointestinal tract, is provided by means such as capsulating a tablet, granule or fine granule wherein the release of active ingredient is controlled and a gel-forming polymer. Said tablet, granule or fine granule has a release-controlled coating-layer formed on a core particle containing an active ingredient.Type: ApplicationFiled: October 15, 2003Publication date: January 19, 2006Inventors: Yohko Akiyama, Takashi Kurasawa, Hiroto Bando, Naoki Nagahara
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Publication number: 20040058956Abstract: Solid dispersions are provided comprising an HER2 inhibitor which is hardly or not soluble in water and a hydrophilic polymer. These solid dispersions have been improved in the solubility of the HER2 inhibitor, oral absorption and bioavailability in blood.Type: ApplicationFiled: June 3, 2003Publication date: March 25, 2004Inventors: Yohko Akiyama, Satoshi Iinuma, Hiroto Bando
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Patent number: 6663883Abstract: This invention provides a matrix adhering to the nasal mucosa which allows improved transfer into the brain of a drug exerting its effect in the brain and is capable of continuously supplying the drug into the brain. This matrix contains a polyglycerol fatty acid ester, the drug exerting its effect in the brain, and a viscogenic substance.Type: GrantFiled: February 21, 2002Date of Patent: December 16, 2003Assignee: Takeda Chemical Industries, Ltd.Inventors: Yoko Akiyama, Naoki Nagahara, Hiroto Bando