Patents by Inventor Hiroto Chaen

Hiroto Chaen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110045137
    Abstract: The objects of the present invention are to provide a method for inhibiting the coloration of a syrupy sweetener, comprising a reducing saccharide together with a non-reducing oligosaccharide having a ?-fructofuranosidic linkage, without deteriorating the taste inherent to the syrupy sweetener; and to provide a syrupy sweetener, comprising a reducing saccharide together with a non-reducing oligosaccharide having a ?-fructofuranosidic linkage, which is stabilized by the method. The present invention attains the above objects by providing a method for inhibiting the coloring of a syrupy sweetener, comprising a reducing saccharide together with a non-reducing oligosaccharide having a ?-fructofuranosidic linkage, which comprises a step of incorporating a lactate into the syrupy sweetener, and by providing a syrupy sweetener, comprising a reducing saccharide together with a non-reducing oligosaccharide having a ?-fructofuranosidic linkage, which is stabilized by the method.
    Type: Application
    Filed: April 27, 2009
    Publication date: February 24, 2011
    Inventors: Kenshi Yoshida, Ikuo Sawatani, Hiroto Chaen, Shigeharu Fukuda, Toshio Miyake
  • Publication number: 20100210589
    Abstract: An object of the present invention is to provide a means for improving hepatic function of mammals including humans to normal condition. The present invention achieves the above object by providing a hepatic function-improving agent comprising ?-glucosyl-hesperidin as an effective ingredient.
    Type: Application
    Filed: April 27, 2010
    Publication date: August 19, 2010
    Applicant: Kabushiki Kaisha Kayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Hitoshi MITSUZUMI, Mika TAKAMI, Yoshikatsu MIWA, Hiroto CHAEN, Toshio MIYAKE
  • Publication number: 20100143389
    Abstract: An object of the present invention is to provide an immunomodulating agent in gut that can be ingested continuously in daily diet without adverse side effect. The object is attained by providing an immunomodulating agent in gut comprising a cyclic tetrasaccharide as an effective ingredient.
    Type: Application
    Filed: September 15, 2006
    Publication date: June 10, 2010
    Inventors: Keiko Hino, Mayumi Kurose, Takeo Sakurai, Shinichiro Inoue, Tohru Ogawa, Kazuyuki Oku, Hiroto Chaen, Shigeharu Fukuda
  • Publication number: 20100129865
    Abstract: An object of the present invention is to provide a novel ketose 3-epimerase, a process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, and a process for producing a ketose by using the enzyme. The present invention solves the above objects by providing a ketose 3-epimerase which is obtainable from a microorganism of the genus Rhizobium, a process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, and a process for converting D- or L-ketohexose into corresponding D- or L-ketohexose by epimerizing the hydroxyl group at the C-3 position of the D- or L-ketohexose; and D- or L-ketopentose into corresponding D- or L-ketopentose by epimerizing the hydroxyl group at the C-3 position of the D- or L-ketopentose; by using the enzyme.
    Type: Application
    Filed: November 6, 2006
    Publication date: May 27, 2010
    Inventors: Kazuhiko Maruta, Kozo Yamamoto, Tomoyuki Nishimoto, Hiroto Chaen, Tetsuya Nakada
  • Publication number: 20100120710
    Abstract: The present invention has objects to provide a glucan useful as water-soluble dietary fiber, its preparation and uses. The present invention solves the above objects by providing a branched ?-glucan, which is constructed by glucose molecules and characterized by methylation analysis as follows: (1) Ratio of 2,3,6-trimethyl-1,4,5-triacetyl-glucitol to 2,3,4-trimethyl-1,5,6-triacetyl-glucitol is in the range of 1:0.6 to 1:4; (2) Total content of 2,3,6-trimethyl-1,4,5-triacetyl-glucitol and 2,3,4-trimethyl-1,5,6-triacetyl-glucitol is 60% or higher in the partially methylated glucitol acetates; (3) Content of 2,4,6-trimethyl-1,3,5-triacetyl-glucitol is 0.5% or higher but less than 10% in the partially methylated glucitol acetates; and (4) Content of 2,4-dimethyl-1,3,5,6-tetraacetyl-glucitol is 0.5% or higher in the partially methylated glucitol acetates; a novel ?-glucosyltransferase which forms the branched ?-glucan, processes for producing them, and their uses.
    Type: Application
    Filed: April 23, 2008
    Publication date: May 13, 2010
    Inventors: Hikaru Watanabe, Takuo Yamamoto, Tomoyuki Nishimoto, Keiji Tsusaki, Kazuyuki Oku, Hiroto Chaen, Shigeharu Fukuda
  • Patent number: 7534458
    Abstract: A process for producing rice flour, which comprises the steps of soaking material rice grains in water, crushing the resulting rice grains, penetrating ?,?-trehalose or maltitol into the rice grains, partially drying the resulting rice grains, and milling the partially dried rice grains; rice flours obtainable by the process; and uses thereof for producing bakery products and noodles.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: May 19, 2009
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Tsuyoshi Sadakiyo, Hideo Bunya, Hiroto Chaen
  • Publication number: 20090022872
    Abstract: An object of the present invention is to provide a novel starchy substance having a retrogradation-resistance, a process for producing the starchy substance efficiently from a material starch by enzymatic reaction, and uses thereof. The present invention attains the above object by providing branched starch having 6-?-maltosyl- and/or 6-?-maltotetraosyl-structure(s) with a marked retrogradation-resistance, a process for producing the branched starch without lowering the molecular weight of material starch, and uses thereof.
    Type: Application
    Filed: March 14, 2006
    Publication date: January 22, 2009
    Inventors: Tomoyuki Nishimoto, Katsuhiko Hino, Takanori Okura, Hiroto Chaen, Shigeharu Fukuda, Toshio Miyake
  • Publication number: 20090018217
    Abstract: The object of the present invention is to establish a volatile sulfide production inhibitor that can inhibit the production of volatile sulfides from a composition and to provide a method for inhibiting the production of volatile sulfides from a composition by using the inhibitor. The object are solved by providing a volatile sulfide production inhibitor comprising L-ascorbic acid 2-glucoside as an effective ingredient and a method for inhibiting the production of volatile sulfides from a composition by incorporating the volatile sulfide production inhibitor into the composition.
    Type: Application
    Filed: February 21, 2007
    Publication date: January 15, 2009
    Inventors: Kazuyuki Oku, Mayumi Kurose, Hiroto Chaen, Toshio Miyake
  • Publication number: 20080221045
    Abstract: An object of the present invention is to provide a means for improving hepatic function of mammals including humans to normal condition. The present invention achieves the above object by providing a hepatic function-improving agent comprising ?-glucosyl-hesperidin as an effective ingredient.
    Type: Application
    Filed: November 21, 2005
    Publication date: September 11, 2008
    Applicant: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Hitoshi Mitsuzumi, Mika Takami, Yoshikatsu Miwa, Hiroto Chaen, Toshio Miyake
  • Patent number: 6762046
    Abstract: A polypeptide having &bgr;-fructofuranosidase activity is obtained by the expression of a microbial gene, which polypeptide contains the amino acid sequences of SEQ ID NO:1 and SEQ ID NO:2 in whole or in part as an amino acid sequence. This polypeptide is useful for producing fructofuranosyl transferred saccharides.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: July 13, 2004
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Keiji Tsusaki, Michio Kubota, Hiroto Chaen
  • Patent number: 6723170
    Abstract: Disclosed are a crystalline trehalose dehydrate which has an elongated crystalline structure with a proportion of the length in the c axis to that in the b axis less than 2.0, its preparation and uses. The crystal has insubstantial hygroscopicity and solidification, and satisfactory stability, free-flowing ability, and handleability; it can be easily processed without fracture in the drying and sieving steps.
    Type: Grant
    Filed: May 2, 2001
    Date of Patent: April 20, 2004
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Tetsuya Ohashi, Hiroto Chaen, Toshio Miyake
  • Patent number: 6576281
    Abstract: Disclosed are a method for inhibiting trimethylamine formation per se from raw fishery products by incorporating trehalose and/or maltitol, an agent having trehalose and/or maltitol as effective ingredients to inhibit trimethylamine formation per se from raw fishery products, and an edible fishery product with satisfactory flavor and taste obtained by using the method or the agent.
    Type: Grant
    Filed: December 17, 1998
    Date of Patent: June 10, 2003
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Hiroto Chaen, Kazuyuki Oku, Toshio Miyake
  • Publication number: 20020115182
    Abstract: A polypeptide having &bgr;-fructofuranosidase activity is obtained by the expression of a microbial gene, which polypeptide contains the amino acid sequences of SEQ ID NO:1 and SEQ ID NO:2 in whole or in part as an amino acid sequence. This polypeptide is useful for producing fructofuranosyl transferred saccharides.
    Type: Application
    Filed: November 9, 2001
    Publication date: August 22, 2002
    Applicant: Kabushiki Kaisha Hayashibara Seibutso Kagaku Kenkyujo
    Inventors: Keiji Tsusaki, Michio Kubota, Hiroto Chaen
  • Patent number: 6432470
    Abstract: A method for improving the aftertaste of sucrose without lowering the sweetening power of sucrose, which comprises incorporating trehalose into sucrose in an amount of 2-12% to the sucrose, on a dry solid basis. The method produces saccharide compositions and food products having improved aftertaste of sucrose without lowering the sweetening power of sucrose.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: August 13, 2002
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Hiroto Chaen, Masakazu Mitsuhashi, Toshio Miyake
  • Publication number: 20020058101
    Abstract: Disclosed are a crystalline trehalose dihydrate which has an elongated crystalline structure with a proportion of the length in the c axis to that in the b axis less than 2.0, its preparation and uses. The crystal has insubstantial hygroscopicity and solidification, and satisfactory stability, free-flowing ability, and handleability; it can be easily processed without fracture in the drying and sieving steps.
    Type: Application
    Filed: July 8, 1999
    Publication date: May 16, 2002
    Inventors: TETSUYA OHASHI, HIROTO CHAEN, TOSHIO MIYAKE
  • Patent number: 6383769
    Abstract: Disclosed are a polypeptide having a &bgr;-fructofuranosidase activity obtainable by the expression of a microbial gene, a DNA encoding the polypeptide, a transformant obtained by introducing the DNA into an appropriate host, a process for producing the polypeptide comprising culturing the transformant to produce the polypeptide and collecting the produced polypeptide from the culture, and a method for fructofuranosyl transfer comprising a step of reacting a fructofuranosyl donor with a fructofuranosyl acceptor in the presence of the polypeptide.
    Type: Grant
    Filed: May 24, 1999
    Date of Patent: May 7, 2002
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Keiji Tsusaki, Michio Kubota, Hiroto Chaen
  • Publication number: 20020006466
    Abstract: A method for improving the aftertaste of sucrose without lowering the sweetening power of sucrose, which comprises incorporating trehalose into sucrose in an amount of 2-12% to the sucrose, on a dry solid basis. The method produces saccharide compositions and food products having improved aftertaste of sucrose without lowering the sweetening power of sucrose.
    Type: Application
    Filed: April 24, 1998
    Publication date: January 17, 2002
    Inventors: HIROTO CHAEN, MASAKAZU MITSUHASHI, TOSHIO MIYAKE
  • Publication number: 20010033888
    Abstract: Disclosed are a crystalline trehalose dehydrate which has an elongated crystalline structure with a proportion of the length in the c axis to that in the b axis less than 2.0, its preparation and uses. The crystal has insubstantial hygroscopicity and solidification, and satisfactory stability, free-flowing ability, and handleability; it can be easily processed without fracture in the drying and sieving steps.
    Type: Application
    Filed: May 2, 2001
    Publication date: October 25, 2001
    Applicant: KABUSHIK KAISHA HAYASHIBARA SEIBUTS KAGAKU KENKYUJO
    Inventors: Tetsuya Ohashi, Hiroto Chaen, Toshio Miyake
  • Patent number: 6294360
    Abstract: A saccharide composition containing trehalulose, which is obtainable by allowing a maltose/trehalose converting enzyme to act on a sucrose solution to produce trehalulose, and collecting the resulting trehalulose-containing mixture. Since the enzyme converts sucrose into trehalulose in a relatively high yield and the conversion rate is controllable, a saccharide composition rich in trehalulose is readily obtained on an industrial scale.
    Type: Grant
    Filed: March 4, 1997
    Date of Patent: September 25, 2001
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Tomoyuki Nishimoto, Hiroto Chaen, Shigeharu Fukuda, Toshio Miyake
  • Patent number: 6268353
    Abstract: A method for inhibiting the formation of volatile aldehydes including their related compounds and/or the decomposition of fatty acids including their related compounds by incorporating trehalose and/or maltitol. Using the method, compositions such as foods, cosmetics, and pharmaceuticals comprising fatty acids can be prepared and stably stored for a relatively-long period of time without fear of forming volatile aldehydes and/or decomposing the fatty acids.
    Type: Grant
    Filed: September 1, 1999
    Date of Patent: July 31, 2001
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Hiroto Chaen, Kazuyuki Oku, Yukio Uchida, Toshio Miyake