Patents by Inventor Hiroto Okayama

Hiroto Okayama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-A, non-B hepatitis virus genomic cDNA and antigen polypeptide
    Patent number: 6217872
    Abstract: Disclosed is an isolated non-A, non-B hepatitis virus genomic CDNA covering the entire region of the virus gene nucleotide sequence from the 1st to 9416th nucleotides shown in FIG. 2(1) through FIG. 2(16) hereof, wherein the coding region is from the 333rd to 9362nd nucleotides, and the 5′- and 3′-noncoding sequences contain 332 nucleotides and 54 nucleotides, respectively. Part of the cDNA and an antigen polypeptide as an expression product thereof are useful as a diagnostic reagent for non-A, non-B hepatitis. The antigen polypeptide is also useful as an active ingredient for a non-A, non-B hepatitis virus vaccine.
    Type: Grant
    Filed: May 21, 1999
    Date of Patent: April 17, 2001
    Assignee: The Research Foundation for Microbial Diseases of Osaka University
    Inventors: Hiroto Okayama, Isao Fuke, Chisato Mori, Akihisa Takamizawa, Iwao Yoshida
  • Non-A, non-B hepatitis virus genomic cDNA and antigen polypeptide
    Patent number: 5998130
    Abstract: Disclosed is an isolated non-A, non-B hepatitis virus genomic cDNA covering the entire region of the virus gene nucleotide sequence from the 1st to 9416th nucleotides shown in FIG. 2(1) through FIG. 2(16) hereof, wherein the coding region is from the 333rd to 9362nd nucleotides, and the 5'- and 3'- noncoding sequences contain 332 nucleotides and 54 nucleotides, respectively. Part of the cDNA and an antigen polypeptide as an expression product thereof are useful as a diagnostic reagent for non-A, non-B hepatitis. The antigen polypeptide is also useful as an active ingredient for a non-A, non-B hepatitis virus vaccine.
    Type: Grant
    Filed: August 1, 1997
    Date of Patent: December 7, 1999
    Assignee: The Research Foundation for Microbial Diseases of Osaka University
    Inventors: Hiroto Okayama, Isao Fuke, Chisato Mori, Akihisa Takamizawa, Iwao Yoshida
  • Non-A, non-B hepatitis virus genomic cDNA and antigen polypeptide
    Patent number: 5847101
    Abstract: Disclosed is an isolated non-A, non-B hepatitis virus genomic cDNA covering the entire region of the virus gene nucleotide sequence from the 1st to 9416th nucleotides shown in FIG. 2(1) through FIG. 2(16) hereof, wherein the coding region is from the 333rd to 9362nd nucleotides, and the 5'- and 3'-noncoding sequences contain 332 nucleotides and 54 nucleotides, respectively. Part of the cDNA and an antigen polypeptide as an expression product thereof are useful as a diagnostic reagent for non-A, non-B hepatitis. The antigen polypeptide is also useful as an active ingredient for a non-A, non-B hepatitis virus vaccine.
    Type: Grant
    Filed: February 6, 1995
    Date of Patent: December 8, 1998
    Assignee: The Research Foundation for Microbial Diseases of Osaka University
    Inventors: Hiroto Okayama, Isao Fuke, Chisato Mori, Akihisa Takamizawa, Iwao Yoshida
  • Oxytocin receptor and DNA coding therefor
    Patent number: 5846766
    Abstract: The present invention relates to a receptor for a posterior pituitary hormone, oxytocin; a DNA sequence encoding for the receptor; a recombinant DNA molecule containing the DNA sequence and a transformant comprising the recombinant DNA molecule. The present invention further relates to methods of detection and diagnosis and a kit to aid in same which comprise either oxytocin, its receptor or antibodies to the receptor.
    Type: Grant
    Filed: June 29, 1995
    Date of Patent: December 8, 1998
    Assignee: Rohto Pharmaceutical Co., Ltd.
    Inventors: Osamu Tanizawa, Hiroto Okayama, Fumitaka Saji, Chihiro Azuma, Tadashi Kimura
  • Non-A, non-B hepatitis virus genomic CDNA and antigen polypeptide
    Patent number: 5747339
    Abstract: Disclosed is an isolated non-A, non-B hepatitis virus genomic cDNA covering the entire region of the virus gene nucleotide sequence from the 1st to 9416th nucleotides shown in FIG. 2(1) through FIG. 2(16) hereof, wherein the coding region is from the 333rd to 9362nd nucleotides, and the 5'- and 3'-noncoding sequences contain 332 nucleotides and 54 nucleotides, respectively. Part of the cDNA and an antigen polypeptide as an expression product thereof are useful as a diagnostic reagent for non-A, non-B hepatitis. The antigen polypeptide is also useful as an active ingredient for a non-A, non-B hepatitis virus vaccine.
    Type: Grant
    Filed: October 18, 1994
    Date of Patent: May 5, 1998
    Assignee: Research Foundation for Microbial Diseases of Osaka
    Inventors: Hiroto Okayama, Isao Fuke, Chisato Mori, Akihisa Takamizawa, Iwao Yoshida
  • Oxytocin receptor and DNA coding therefor
    Patent number: 5466584
    Abstract: The present invention relates to a receptor for a posterior pituitary hormone, oxytocin; a DNA sequence encoding for the receptor; a recombinant DNA molecule containing the DNA sequence and a transformant comprising the recombinant DNA molecule. The present invention further relates to methods of detection and diagnosis and a kit to aid in same which comprise either oxytocin, its receptor or antibodies to the receptor.
    Type: Grant
    Filed: October 8, 1992
    Date of Patent: November 14, 1995
    Assignee: Rohto Pharmaceutical Co., Ltd.
    Inventors: Osamu Tanizawa, Hiroto Okayama, Fumitaka Saji, Chihiro Azuma, Tadashi Kimura