Abstract: An object of the present invention is to provide a method of comprehensively visualizing a constituent in tumor tissue or the like at a cellular level. The present invention provides a method of forming a two-dimensional distribution image of a target constituent based on information on the mass of constituents of the tissue section wherein, as the internal standard material, any one of actin, tubulin and GAPDH is used in the intracellular region, one of histone and nucleic acid is used in the nuclear region, and one of albumin and cytokine is used in the extracellular region.

Abstract: The present invention intends to provide a high sensitivity method for identifying the type of a protein contained in each cell with a diameter of ten to several tens ?m and a sample treatment solution required for it. The above is achieved by three steps of (1) treating a slice of a diseased tissue with an aqueous solution containing gold particles and a digestive enzyme, and digesting restrictively a protein of interest, (2) measuring a 2-dimensional distribution of fragmented peptides by TOF-SIMS, and (3) visualizing a 2-dimensional distribution of the target protein in the slice of the diseased tissue using the results of the proteome analysis and by means of a numerical analysis.

Abstract: Target molecules in a sample can be detected at an improved sensitivity by means of a mass spectrometer. A sample with or without a matrix is placed on a substrate and irradiated with a converged and pulsed primary beam selected from an ion beam, a neutral particle beam or a laser beam. Secondary ions and neutral molecules are emitted along with protons from the irradiated point of the sample as an electric field is applied between the substrate and an extraction electrode disposed above the substrate. A proton-control electrode is arranged in axial symmetry with the trajectory of the primary beam. A voltage is applied thereto so that the generated electric field decelerates the flying protons to raise their adhering efficiency to the flying neutral molecules.

Abstract: There is provided a laminate comprising a hard coat layer having the outermost surface to which slipperiness has been imparted. The laminate comprises a transparent substrate and a hard coat layer provided on said transparent substrate. The hard coat layer is formed of a cured product of a composition comprising a fluorine-modified urethane acrylate and/or a polydimethylsiloxane having a polyether-modified acryl or polyether group.

Abstract: A test specimen that has one or more chemical substances fixed to prescribed plural independent positions on a substrate, and the quantities of the chemical substances fixed at the respective prescribed positions are the total of integer multiples of existence quantity units defined for the respective chemical substances in the range from 1 amol to 1 nmol (excluding the case in which the total quantity is zero).

Abstract: A computer connectable image display apparatus for presentation is provided. The image display apparatus has a candidate information obtaining unit, a selection screen display unit, a presentation execution instruction unit, and a drawing screen display unit. The candidate information obtaining unit obtains selection candidate information generated by the computer relating selection candidates for a presentation subject file. The selection screen display unit generates and displays a selection screen for selecting the presentation subject file based on the selection candidate information. The presentation execution instruction unit makes the computer to execute the selected presentation subject file by sending selection results with the selection screen. The drawing screen display unit captures and displays a computer drawing screen drawn by the computer.

Abstract: [Problem] To realize a predetermined “aseptic level of the containers” without introducing a container sterilizing machine and to reduce the burden for adjusting the temperature of the preform. [Means for Solution] A metal mold for molding, wherein a space width (t2) of at least the body portion in the space width for forming a thickness of from the body portion to the bottom portion of the preform is set to lie in a range of 1.18 to 2.11 times as great as a space width (t1) for forming a thickness of an upper end portion of the mouth portion of the preform. At the time of the compression molding, the preform is taken out in the state of a high temperature from a compression-molding machine 31 and is fed to a bottle-producing unit C while maintaining the state of a high temperature. Further, the inner surfaces of a clean box I in which the units are placed and the outer surfaces of the units are sterilized, and the interior of the clean box I maintains a positive-pressure state with the filtered clean air.

Abstract: In-plane distribution of a target object contained in a sample is measured. The sample dispersedly placed on a substrate is treated to promote ionization of the target object. Then, the mass and flying amount of an ion containing the target object or a component thereof is determined by irradiating an ion beam to the sample and performing time-of-flight secondary ion mass spectrometry of the ion that flies from a portion in the sample where the ion beam is irradiated, and the in-plane distribution of the target object is determined from the mass and flying amount data obtained at plural portions by scanning the beam on the sample plane. The step of treating the sample to promote ionization of the target object includes contacting an aqueous solution of an acid that does not crystallize at ordinary temperature with the sample. A high spatial resolution two-dimensional image can be obtained.

Abstract: A control device that controls a plurality of air conditioners includes a data memory section for storing performance model data representing the relationship between air conditioning capability and power consumption for each of the plurality of air conditioners. An overall air conditioning load calculating section calculates an overall load that is the sum of air conditioning loads of the plurality of air-conditioning apparatuses. An air conditioning capability allocation calculating section an air conditioning capability for each of the plurality of air conditioners on the basis of the performance model data and the overall load so that the sum of the air conditioning capability of the plurality of air conditioners is the overall load and the sum of the power consumption of the plurality of air conditioners is minimum. A control signal section sends a control signal related to the air conditioning capability to each of the plurality of air conditioners.

Abstract: To provide a beverage dispenser capable of appropriately and smoothly supplying a supercooled beverage. According to the present invention, there is disclosed a beverage dispenser including a beverage supply circuit 7 which supplies a carbonated beverage to the outside a primary cooling device 13, a secondary cooling device 30, and a heat exchanger 16 for supercooling which allows these components to cool the carbonated beverage flowing through the beverage supply circuit 7 into a supercooled state at a temperature of a solidifying point or less. The heat exchanger 16 supplies the carbonated beverage in the supercooled state to release the supercooled state in the outside, and the carbonated beverage on standby for serving in a portion of the beverage supply circuit 7 cooled by at least the heat exchanger 16 for supercooling is maintained in an unsaturated state.

Abstract: To provide a beverage dispenser capable of appropriately and smoothly supplying a carbonated beverage as a supercooled beverage. According to the present invention, there is disclosed a beverage dispenser including a carbonator 51 for manufacturing carbonated water; a beverage supply circuit 7 for supplying a carbonated beverage manufactured by the carbonator 51 to the outside; a heat exchanger 16 for supercooling; and a primary cooling device 13, the carbonator 51 mixes a carbonic acid gas supplied from a gas regulator 54 which supplies a pressurized carbonic acid gas, syrup and diluting water to manufacture the carbonated beverage, and the heat exchanger 16 for supercooling cools the carbonated beverage flowing through the beverage supply circuit 7 into a supercooled state at a temperature of a solidifying point or less to release the supercooled state in the outside.

Abstract: An aqueous solution containing an adhesion promoter in an amount of 20 vol. % or more is heated and vaporized to a temperature of 80 to 100° C. to produce a water-containing adhesion promoter vapor, and the water-containing adhesion promoter vapor is adhered to and condensed on a surface of a substrate, to cause a heating and dehydrating reaction by which the adhesion promoter is adhered to the surface of the substrate.

Abstract: A method for obtaining information on a mass of an object by time-of-flight mass spectrometry. This method includes placing colloidal metal particles for promoting ionization of the object inside the object at a depth ranging from 0.1 nm to 100 nm in opposition to a primary beam for the ionization; irradiating the object with the primary beam selected from the group of ions, neutral particles, and electrons, which can be focused, pulsed, and are capable of scanning, and laser beams, which can be focused, pulsed, and are capable of scanning to ionize a constituent of the object and to allow the ionized constituent to fly out of the object; and obtaining information on the mass of the flying constituent of the object by time-of-flight mass spectrometry.

Abstract: There is disclosed a beverage dispenser capable of appropriately and smoothly supplying a supercooled beverage without being influenced by a type of raw water. The present invention is a beverage dispenser 1 comprising: a raw water treatment device 63 which deaerates raw water and/or filters the raw water through a reverse osmosis film; a primary cooling device 13 which cools said raw water to an ice point or so; a raw water supply circuit 59 which supplies the raw water cooled by the primary cooling device 13 to the outside; a secondary cooling device 30 which cools the raw water flowing through the raw water supply circuit 59 into the supercooled state at the solidifying point or less; and a syrup circuit 53 which supplies a syrup to the raw water supplied to the outside through a heat exchanger 61 for supercooling the raw water of the secondary cooling device 30.

Abstract: To provide a beverage dispenser capable of appropriately and smoothly supplying a supercooled beverage. [Solving Means] The present invention provides a beverage dispenser 1 which supplies a beverage brought into a supercooled state at a solidifying point or less and which releases the supercooled state in the outside, and the beverage dispenser includes a primary cooling device 13 which cools the beverage to an ice point or so, a beverage supply circuit 7 which supplies the beverage cooled by the primary cooling device 13 to the outside, a brine circuit 31 through which an antifreezing liquid cooled to the solidifying point or less of the beverage is circulated, and a heat exchanger 16 for supercooling the beverage, which performs heat exchange between the beverage flowing through the beverage supply circuit 7 and the antifreezing liquid flowing through the brine circuit 31.

Abstract: An information obtaining method for obtaining information about a mass of a component of an analyte using a time of flight mass spectrometer and obtaining information about a distribution state of the component based on the obtained information about the mass includes the step of: (1) adding a self-reactive substance to the analyte on a base to facilitate ionization of the component; (2) irradiating the analyte with a primary beam in the presence of the self-reactive substance, thereby ionizing the components and allowing resulting ions to fly; (3) obtaining information about mass of the flying ions using the time of flight mass spectrometer; and (4) obtaining information about the distribution state of the component on the base based on the information about the mass.

Abstract: An information acquisition method for acquiring information on a target object, that includes a step of promoting ionization of the target object using a substance for promoting ionization of the target object to cause the target object to emit, and a step of acquiring information on the mass of the flew target object using time-of-flight secondary ion mass spectrometry.

Abstract: Provided is an organic electroluminescence element which is driven with a reduced drive voltage without deteriorating emission luminance and has a high power efficiency. The organic electroluminescence element having at least one light emitting layer is characterized in that two or more types of light emitting dopants having different emission colors are included in at least one light emitting layer, the concentration of all the light emitting dopants included in the light emitting layer is 5 Vol % or more, and the concentration of the light emitting dopant giving a main emission color among the light emitting dopants in the light emitting layer is 2 Vol % or less.

Abstract: [Problems] To provide an apparatus for feeding resin capable of extinguishing angular traces formed at both end portions of the cutter mark or of preventing the angular traces from extending up to the side wall of the body portion of the preform at the time of forming a preform. [Means for Solution] An apparatus for feeding molten resin to a compression-molding machine, including a holding unit 17 that rotates on a track, the holding unit 17 having a pair of holders 22 and 23 capable of holding and releasing the molten resin. When the molten resin is cut by a cutter, a linear cutter mark 29 is formed on the cut surface of the resin in a direction at right angles with the direction in which the molten resin is cut. Protruded portions 32 and 33 are formed on the inner circumferential surfaces of the holders 22 and 23 to deform the end portions of the cutter mark 29 toward the inside of the cutter mark when the molten resin is held by the pair of holders 22 and 23.

Abstract: An apparatus for feeding a molten resin is operated for extended periods of time maintaining stability without permitting volatile components of the molten resin to adhere on the surfaces of conveyer means. An extruder in the apparatus for feeding the molten resin to the compression-forming machine has an extrusion unit which discharges a molten resin through an extrusion opening of an extrusion nozzle. An air injection nozzle for injecting the cooling gas is provided along the outer circumference of the extrusion nozzle, and the cooling gas is blown onto the surface of the molten resin extruded from the extrusion opening to cool the surface of the molten resin.