Patents by Inventor Hisakazu Mihara

Hisakazu Mihara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8148141
    Abstract: Disclosed is a peptide-immobilized substrate for measuring a target protein, with which the peptide can have a structure required for being recognized by the target protein, with which the accurate loading amount of the peptide can be attained, and by which a trace amount of the target protein may be measured accurately and simply. The peptide-immobilized substrate for measuring a target protein according to the present invention comprises a chemically synthesized peptide having an expected spatial structure or having a binding ability with the target protein, which peptide can bind with the target protein and is immobilized on the substrate.
    Type: Grant
    Filed: May 7, 2002
    Date of Patent: April 3, 2012
    Assignee: HiPep Laboratories
    Inventors: Kiyoshi Nokihara, Hisakazu Mihara
  • Patent number: 7592167
    Abstract: This invention provides a functional peptide fiber which comprises a plurality of peptide structure units each containing at least one peptide chain, wherein peptide chains contained in each adjacent peptide structure units do not form peptide bond but are structured into a fibrous form by taking a ?-sheet structure, and wherein at least one of the plurality of peptide structure units contains a peptide chain having a functional material connected thereto. Also disclosed are a method for producing the functional peptide fiber and a method for recovering peptide chains from the functional peptide fiber.
    Type: Grant
    Filed: September 5, 2007
    Date of Patent: September 22, 2009
    Assignee: Fuji Xerox Co., Ltd.
    Inventor: Hisakazu Mihara
  • Publication number: 20080199934
    Abstract: This invention provides a functional peptide fiber which comprises a plurality of peptide structure units each containing at least one peptide chain, wherein peptide chains contained in each adjacent peptide structure units do not form peptide bond but are structured into a fibrous form by taking a ?-sheet structure, and wherein at least one of the plurality of peptide structure units contains a peptide chain having a functional material connected thereto. Also disclosed are a method for producing the functional peptide fiber and a method for recovering peptide chains from the functional peptide fiber.
    Type: Application
    Filed: September 5, 2007
    Publication date: August 21, 2008
    Applicant: FUJI XEROX CO., LTD.
    Inventor: Hisakazu Mihara
  • Publication number: 20060235199
    Abstract: There are disclosed a natural peptide search in which a template reaction with the nucleus of a minute amount of amyloid ?-protein having undergone amyloid fibrosis is induced so as to form amyloid fibers, followed by fiber amount increase and amplification; designing and development of a novel artificial peptide which can be a substitute therefor; a method of amplifying the amyloid fibrosis of amyloid ?-protein with the use thereof and a reagent for use therein; and a method of detecting disease caused by amyloidosis and a reagent for use therein.
    Type: Application
    Filed: June 21, 2004
    Publication date: October 19, 2006
    Inventors: Hisakazu Mihara, Tsuyoshi Takahashi, Hideo Ooshima
  • Publication number: 20050084902
    Abstract: Disclosed is a peptide-immobilized substrate for measuring a target protein, with which the peptide can have a structure required for being recognized by the target protein, with which the accurate loading amount of the peptide can be attained, and by which a trace amount of the target protein may be measured accurately and simply. The peptide-immobilized substrate for measuring a target protein according to the present invention comprises a chemically synthesized peptide having an. expected spatial structure or having a binding ability with the target protein, which peptide can bind with the target protein and is immobilized on the substrate.
    Type: Application
    Filed: May 7, 2002
    Publication date: April 21, 2005
    Inventors: Kiyoshi Nokihara, Hisakazu Mihara
  • Publication number: 20030162696
    Abstract: This invention provides a functional peptide fiber which comprises a plurality of peptide structure units each containing at least one peptide chain, wherein peptide chains contained in each adjacent peptide structure units do not form peptide bond but are structured into a fibrous form by taking a &bgr;-sheet structure, and wherein at least one of the plurality of peptide structure units contains a peptide chain having a functional material connected thereto. Also disclosed are a method for producing the functional peptide fiber and a method for recovering peptide chains from the functional peptide fiber.
    Type: Application
    Filed: September 12, 2002
    Publication date: August 28, 2003
    Applicant: FUJI XEROX CO., LTD.
    Inventor: Hisakazu Mihara