Abstract: There are provided a capsule and a chemical reaction cartridge capable of properly handling reagents and so forth. The capsule is formed by laminating two dome-shaped films together at the peripheries thereof. The films are formed by subjecting heat sealable films, to which aluminum vapor deposition is applied, to a drawing process. The films are made of a material (easy-peel material), which can be varied in seal strength by a heating temperature and are thermally welded together at an adhesion area at the peripheries thereof. Thereafter, contents such as reagents and so forth are filled up inside the capsule via a filling section.

Abstract: The present invention makes it possible to realize a chemical reaction cartridge, which enables prescribed protocols to be achieved easily without differences among operators. The cartridge is sealed and disposable, and has a safe structure against viruses or dangerous drugs. This cartridge is intended to be used for performing chemical reaction of samples. The cartridge comprises a container formed of a rigid substrate and an elastic body, wherein two or more chambers linked or arranged to be able to be linked through flow paths are formed in the container. The flow paths, the chambers or both are partially closed by applying an external force to the elastic body from outside the container, thereby being able to move or block fluid substance in said flow paths or chambers.

Abstract: A chemical reaction cartridge includes a vessel having at least one part made of an elastic body, in which a plurality of chambers formed in the vessel so as to be connected or arranged connectably through a flow path, and an external force is applied to the elastic body from an outside of the vessel to move a fluid substance in the flow path or the chambers or in both the flow path and the chambers so as to perform a chemical reaction. At least a chamber into which the fluid substance is flowed has an air-release path which releases air from the chamber.

Abstract: An end portion of a head has a recess having an inner shape corresponding to a dome shape of a well when the well is in an expanded state. The radius of curvature of the recess is larger than the radius of curvature of the dome shape of the well. Moreover, the depth of the recess is smaller than the height of the dome shape of the well. Therefore, the head first contacts the apex of the well, and the contact area gradually expands toward the outer periphery. At this time, a gap is generated between the head and the cartridge around the well. Thus, the air between the head and the well is expelled from around the well as the head is pressed against the well.

Abstract: There are provided a capsule and a chemical reaction cartridge capable of properly handling reagents and so forth. The capsule is formed by laminating two dome-shaped films together at the peripheries thereof. The films are formed by subjecting heat sealable films, to which aluminum vapor deposition is applied, to a drawing process. The films are made of a material (easy-peel material), which can be varied in seal strength by a heating temperature and are thermally welded together at an adhesion area at the peripheries thereof. Thereafter, contents such as reagents and so forth are filled up inside the capsule via a filling section.

Abstract: A cartridge for chemical processing carries out chemical processing while moving a content by deformation based on an externally applied force, and includes a microarray chip housed in the cartridge for chemical processing; a member having a surface that faces a surface of the microarray chip; a supporting unit for supporting the member such that a width of a gap between the member and the microarray chip is variable by the externally applied force; and a limiting unit for restricting a variable range of the gap by the supporting unit such that the width of the entire gap between the surface of the member and the surface of the microarray chip does not become smaller than a predetermined width.

Abstract: Disclosed is a chemical reaction cartridge including an elastic body with which at least a portion of the chemical reaction cartridge is formed and a plurality of chambers and a flow path to connect the plurality of chambers, which contain solution inside, and the solution is moved or blocked in the chambers and the flow path by applying external force to the elastic body from outside, the elastic body is structured in at least two elastic body layers which are layered vertically and the plurality of chambers and the flow path are provided between an upper elastic body layer and a lower elastic body layer, and the elastic body is attached to a surface of a substrate made of hard material.

Abstract: A cartridge adaptable to various measurement forms is provided. A sample is injected into a well via an injection path. When a roller while kept pressed into contact with the cartridge is rotated rightward, the sample held in the well, and liquid solvent held in a well are caused to reach a well via flow paths, respectively, thereby mixing the sample with the liquid solvent. A mixed liquid is branched into flow paths, respectively, to thereby reach wells, respectively, and reagents pre-held in wells, respectively, are caused to flow into the wells, respectively. Next, temperatures in the wells, respectively, are controlled, thereby executing DNA amplification. Then, PCR by-products as amplified in the wells, respectively, are transferred as far as a position in the vicinity of an electrode via flow paths.

Abstract: The present invention describes a disposable chemical reaction cartridge comprising a container formed of a rigid substrate and an elastic body, wherein two or more chambers are linked or configured to be linked through flow paths, and wherein the flow paths, the chambers or both, can be partially closed by applying an external force to the elastic body from outside of the container, to move or block fluids in the flow paths or chambers. The cartridge has a structure protected against viruses or dangerous drugs and facilitates foolproof implementation of prescribed protocols for the samples to be tested.

Abstract: The present invention makes it possible to realize a chemical reaction cartridge, which enables prescribed protocols to be achieved easily without differences among operators, which is sealed and disposable, and which has a safe structure against viruses or dangerous drugs. This cartridge is intended to be used for performing chemical reaction of samples, comprising a container formed of a rigid substrate and an elastic body, wherein two or more chambers linked or arranged to be able to be linked through flow paths are formed in said container, and wherein said flow paths, said chambers or both are partially closed by applying an external force to said elastic body from outside said container, thereby being able to move or block fluid substance in said flow paths or chambers.

Abstract: There are provided a capsule and a chemical reaction cartridge capable of properly handling reagents and so forth. The capsule is formed by laminating two dome-shaped films together at the peripheries thereof. The films are formed by subjecting heat sealable films, to which aluminum vapor deposition is applied, to a drawing process. The films are made of a material (easy-peel material), which can be varied in seal strength by a heating temperature and are thermally welded together at an adhesion area at the peripheries thereof. Thereafter, contents such as reagents and so forth are filled up inside the capsule via a filling section.

Abstract: The invention provides a chemical reaction cartridge which can be treated with safety upon introduction of a sample into the cartridge and a method of using the same. An opening section of the chemical reaction cartridge is openable and closable by a rail fastener provided inside an elastic body. When the rail fastener is released, the elastic body can be opened across the entire width. The opening section provides the cartridge with an opening having a large sectional area, which is larger than a flow path and a chamber inside the cartridge, owing to elasticity of the elastic body.

Abstract: A separation method of single-stranded nucleic acid characterized in that nucleic acid amplification is performed using a first primer to which a second substance capable of binding specifically to a first substance is bound and a second primer to which the second substance is not bound, and double-stranded nucleic acid obtained by the nucleic acid amplification is bound to the first substance, and the double-stranded nucleic acid bound to the first substance is dissociated into a single strand, and a separation apparatus of single-stranded nucleic acid characterized by having a nucleic acid amplification part 1 for performing nucleic acid amplification using a first primer to which a second substance capable of binding specifically to a first substance is bound and a second primer to which the second substance is not bound, a binding part 2 for binding double-stranded nucleic acid obtained by the nucleic acid amplification to the first substance, and a dissociation part 3 for dissociating the double-stranded

Abstract: Disclosed is a chemical reaction cartridge including an elastic body with which at least a portion of the chemical reaction cartridge is formed and a plurality of chambers and a flow path to connect the plurality of chambers, which contain solution inside, and the solution is moved or blocked in the chambers and the flow path by applying external force to the elastic body from outside, the elastic body is structured in at least two elastic body layers which are layered vertically and the plurality of chambers and the flow path are provided between an upper elastic body layer and a lower elastic body layer, and the elastic body is attached to a surface of a substrate made of hard material.

Abstract: Disclosed is a chemical reaction cartridge comprising: an elastic member as a component; a flow path and a plurality of chambers which are connected to each other by the flow path, the flow path or the chambers or both of the flow path and the chambers being partially blocked by applying external pressure to the elastic member from outside so that a fluid substance in the flow path or in the chambers is moved or blocked, and one of the chambers being a sample collecting chamber to temporarily retain a sample supplied from outside; an insert section to insert an injection needle to inject the sample into the sample collecting chamber; and a sealing member in which an opening to accept the injection needle inserted into the insert section is formed, and the opening is sealed to seal the insert section.

Abstract: The equipment of the present invention can implement high-speed hybridization with a simple construction and is configured as described below. The equipment comprises a biochip prepared by fixing biopolymers onto a plurality of sites on a substrate, positive and negative electrodes for generating an electric field along the surface of this biochip substrate, and a magnetic field generating means for generating a magnetic field along the surface of the above biochip substrate, and is configured to move biopolymers movable in the fluid stored over the above-mentioned biochip substrate along the surface of the above biochip substrate as well as to attract the above described biopolymers towards the surface of the above biochip substrate during hybridization of the above biopolymers, by making the above-mentioned electric and magnetic fields act along the surface of the above biochip substrate.

Abstract: A cartridge adaptable to various measurement forms is provided. A sample is injected into a well via an injection path. When a roller while kept pressed into contact with the cartridge is rotated rightward, the sample held in the well, and liquid solvent held in a well are caused to reach a well via flow paths, respectively, thereby mixing the sample with the liquid solvent. A mixed liquid is branched into flow paths, respectively, to thereby reach wells, respectively, and reagents pre-held in wells, respectively, are caused to flow into the wells, respectively. Next, temperatures in the wells, respectively, are controlled, thereby executing DNA amplification. Then, PCR by-products as amplified in the wells, respectively, are transferred as far as a position in the vicinity of an electrode via flow paths.

Abstract: The cartridge for chemical reaction according to the invention is a cartridge for chemical reaction that causes chemical reaction by feeding an internal liquid by way of deformation caused by external forces. The entirety of a target molecule detecting chip is housed in the cartridge for chemical reaction. According to the cartridge for chemical reaction, the entire target molecule detecting chip is housed in the cartridge for chemical reaction so that it supports various forms of target molecule detecting chips. The target molecule detecting chip may be a penetration type chip that allows a solution including target molecules to penetrate the target molecule detecting chip. In this case, the solution may pass inside the penetration type chip by way of deformation of the cartridge for chemical reaction caused by external forces applied to the cartridge for chemical reaction.

Abstract: Detector calibration methods are described which enable the measurement of absolute power. The method includes using a power meter with traceability to the national standard for optical power to calibrate the power of each photodetector device of a detector with photodetector device arrays arranged in one dimension or two dimensions and to calibrate the output signals of the detector making it possible to measure the spatial distribution of a light source's power and also values of optical power with traceability to the national standard directly from the output signals of the detector.

Abstract: The equipment of the present invention can implement high-speed hybridization with a simple construction and is configured as described below. The equipment comprises a biochip prepared by fixing biopolymers onto a plurality of sites on a substrate, positive and negative electrodes for generating an electric field along the surface of this biochip substrate, and a magnetic field generating means for generating a magnetic field along the surface of the above biochip substrate, and is configured to move biopolymers movable in the fluid stored over the above-mentioned biochip substrate along the surface of the above biochip substrate as well as to attract the above described biopolymers towards the surface of the above biochip substrate during hybridization of the above biopolymers, by making the above-mentioned electric and magnetic fields act along the surface of the above biochip substrate.