Patents by Inventor Hitarth Harshendu Acharya
Hitarth Harshendu Acharya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120095239Abstract: The present invention relates to a process for the preparation of Duloxetine hydrochloride of formula (I).Type: ApplicationFiled: March 5, 2010Publication date: April 19, 2012Applicant: ALEMBIC PHARMACEUTICALS LIMITEDInventors: Ravi Ponnaiah, Ashok Prasad, Killol Patel, Hitarth Harshendu Acharya
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Publication number: 20110275836Abstract: The present invention relates to improved process for the preparation of Duloxetine of formula (I) and salts thereof wherein said improvement takes place in step of condensation.Type: ApplicationFiled: December 28, 2009Publication date: November 10, 2011Applicant: ALEMBIC PHARMACEUTICALS LIMITEDInventors: Ravi Ponnaiah, Ashok Prasad, Killol Patel, Hitarth Harshendu Acharya, Vilas Katore, Bhavik Shah
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Patent number: 7968731Abstract: An improved process is described for the purification of ropinirole hydrochloride. The process includes (i) dissolving ropinirole hydrochloride in water; (ii) treating the solution obtained in step (i) with sodium dithionate and charcoal; (iii) treating the filtrate obtained in step (ii) with water immiscible solvent and base and isolating the free base; and (iv) treating the free base obtained in step (iii) with ethanolic HCl to give ropinirole hydrochloride.Type: GrantFiled: March 21, 2007Date of Patent: June 28, 2011Assignee: Alembic LimitedInventors: Pandurang Balwant Deshpande, Ashok Prataprai Shanishchara, Trushar Rajanikant Shah, Hitarth Harshendu Acharya, Parven Kumar Luthra
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Patent number: 7863462Abstract: The present invention provides an improved process for the purification of ropinirole hydrochloride. The process includes (i) treating ropinirole hydrochloride with sodium dithionate and charcoal in suitable alcoholic solvent; (ii) triturating the ropinirole hydrochloride obtained in step (i) with ethanol; (iii) reacting the triturated solid with base in water immiscible solvent and isolating the free base; and (iv) treating the free base obtained in step (iii) with ethanolic HCl to give ropinirole hydrochloride.Type: GrantFiled: March 21, 2007Date of Patent: January 4, 2011Assignee: Alembic LimitedInventors: Pandurang Balwant Deshpande, Parven Kumar Luthra, Hitarth Harshendu Acharya
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Publication number: 20100249433Abstract: An improved process is described for the purification of ropinirole hydrochloride. The process includes (i) dissolving ropinirole hydrochloride in water; (ii) treating the solution obtained in step (i) with sodium dithionate and charcoal; (iii) treating the filtrate obtained in step (ii) with water immiscible solvent and base and isolating the free base; and (iv) treating the free base obtained in step (iii) with ethanolic HCl to give ropinirole hydrochloride.Type: ApplicationFiled: March 21, 2007Publication date: September 30, 2010Applicant: ALEMBIC LIMITEDInventors: Pandurang Balwant Deshpande, Ashok Prataprai Shanishchara, Trushar Rajanikant Shah, Hitarth Harshendu Acharya, Parven Kumar Luthra
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Publication number: 20100179332Abstract: The present invention provides an improved process for the purification of ropinirole hydrochloride. The process includes (i) treating ropinirole hydrochloride with sodium dithionate and charcoal in suitable alcoholic solvent; (ii) triturating the ropinirole hydrochloride obtained in step (i) with ethanol; (iii) reacting the triturated solid with base in water immiscible solvent and isolating the free base; and (iv) treating the free base obtained in step (iii) with ethanolic HCl to give ropinirole hydrochloride.Type: ApplicationFiled: March 21, 2007Publication date: July 15, 2010Applicant: Alembic LimitedInventors: Pandurang Balwant Deshpande, Parven Kumar Luthra, Hitarth Harshendu Acharya
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Patent number: 7683205Abstract: The present invention relates to an improved process for preparation of Rivastigmine of formula (I) or pharmaceutically acceptable salts thereof comprising a step of N-methylation of compound of formula (III), wherein R1=R2=H or R1=H and R2=CH3 or an acid addition salt thereof, using paraformaldehyde in the presence of Raney Nickel and hydrogen in a suitable solvent to obtain compound of formula (II).Type: GrantFiled: October 31, 2006Date of Patent: March 23, 2010Assignee: Alembic LimitedInventors: Pandurang Balwant Deshpande, Kishore Khemani, Bharat Becharbhai Boda, Tushar Rajnikant Shah, Hitarth Harshendu Acharya, Parven Kumar Luthra
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Patent number: 7619095Abstract: A process for the preparation of 4-[2-(Di-n-propylamino)ethyl]-2,3-dihydro-1H-indol-2-one of formula (I) and its pharmaceutically acceptable salts, solvates Formula I involving new intermediates of compound of formula (A) and (B) wherein R represents (i) a halogen atom selected from fluorine, chlorine atom, bromine atom and iodine atom; (ii) lower alkanesulfonyloxy group selected from methanesulfonyloxy, ethanesulfonyloxy, isopropanesulfonyloxy, propanesulfonyloxy, butanesulfonyloxy, tert-butanesulfonyloxy, pentanesulfonyloxy, hexanesulfonyloxy; (iii) substituted or unsubstantiated arylsulfonyloxy group selected from phenylsulfonyloxy, 4-methylphenylsulfonyloxy, 2-methylphenylsulfonyloxy, 4-nitrophenylsulfonyloxy, 4-methoxyphenylsulfonyloxy, 3-chlorophenylsulfonyloxy; (iv) arylalkylsulfonyloxy group selected from benzylsulfonyloxy, 2-phenylethylsulfonyloxy, 4-phenylbutylsulfonyloxy, 4-methylbenzylsulfonyloxy, 2-methylbenzylsulfonyloxy, 4-nitrobenzylsulfonyloxy, 4-methoxybenzylsulfonyloxy, 3-chlorobenzylsulfonType: GrantFiled: February 15, 2006Date of Patent: November 17, 2009Assignee: Alembic LimitedInventors: Rohit Ravikant Soni, Hitarth Harshendu Acharya, Hetal Rameshchandra Shah, Trushar Rajnikant Shah, Buchi Reguri Reddy
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Publication number: 20080262244Abstract: A process for the preparation of 4-[2-(Di-n-propylamino)ethyl]-2,3-dihydro-1H-indol-2-one of formula (I) and its pharmaceutically acceptable salts, solvates Formula I involving new intermediates of compound of formula (A) and (B) wherein R represents (i) a halogen atom selected from fluorine, chlorine atom, bromine atom and iodine atom; (ii) lower alkanesulfonyloxy group selected from methanesulfonyloxy, ethanesulfonyloxy, isopropanesulfonyloxy, propanesulfonyloxy, butanesulfonyloxy, tert-butanesulfonyloxy, pentanesulfonyloxy, hexanesulfonyloxy; (iii) substituted or unsubstantiated arylsulfonyloxy group selected from phenylsulfonyloxy, 4-methylphenylsulfonyloxy, 2-methylphenylsulfonyloxy, 4-nitrophenylsulfonyloxy, 4-methoxyphenylsulfonyloxy, 3-chlorophenylsulfonyloxy; (iv) arylalkylsulfonyloxy group selected from benzylsulfonyloxy, 2-phenylethylsulfonyloxy, 4-phenylbutylsulfonyloxy, 4- methylbenzylsulfonyloxy, 2-methylbenzylsulfonyloxy, 4-nitrobenzylsulfonyloxy, 4-methoxybenzylsulfonyloxy, 3-chlorobenzylsulfoType: ApplicationFiled: February 15, 2006Publication date: October 23, 2008Applicant: Alembic LimitedInventors: Rohit Ravikant Soni, Hitarth Harshendu Acharya, Hetal Rameshchandra Shah, Trushar Rajnikant Shah, Buchi Reguri Reddy
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Publication number: 20080045743Abstract: The present invention relates to an improved process for preparation of Rivastigmine of formula (I) or pharmaceutically acceptable salts thereof comprising a step of N-methylation of compound of formula (III), wherein R1=R2=H or R1=H and R2=CH3 or an acid addition salt thereof, using paraformaldehyde in the presence of Raney Nickel and hydrogen in a suitable solvent to obtain compound of formula (II).Type: ApplicationFiled: October 31, 2006Publication date: February 21, 2008Applicant: ALEMBIC LIMITEDInventors: Pandurang Balwant Deshpande, Kishore Khemani, Bharat Becharbhai Boda, Tushar Rajnikant Shah, Hitarth Harshendu Acharya, Parven Kumar Luthra