Patents by Inventor Hitendra S. Chand

Hitendra S. Chand has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Long noncoding RNAs in pulmonary airway inflammation
    Patent number: 10851376
    Abstract: The subject invention provides methods, assays, and products for preventing and/or treating pulmonary diseases. The present invention provides methods for identifying inhibitors of lncRNAs, pharmaceutical compositions comprising such inhibitors, and method of using said inhibitors in preventing and/or treating pulmonary airway inflammation. The present invention also develop novel strategies to modulate the mucous response for preventing, intervening, diagnosing and treating pulmonary airway inflammation, asthma, chronic obstructive pulmonary diseases (COPD) and Chronic mucus hypersecretion (CMH) pathogenesis.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: December 1, 2020
    Assignee: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES
    Inventors: Hitendra S. Chand, Madhavan Nair
  • LONG NONCODING RNAS IN PULMONARY AIRWAY INFLAMMATION
    Publication number: 20200208153
    Abstract: The subject invention provides methods, assays, and products for preventing and/or treating pulmonary diseases. The present invention provides methods for identifying inhibitors of lncRNAs, pharmaceutical compositions comprising such inhibitors, and method of using said inhibitors in preventing and/or treating pulmonary airway inflammation. The present invention also develop novel strategies to modulate the mucous response for preventing, intervening, diagnosing and treating pulmonary airway inflammation, asthma, chronic obstructive pulmonary diseases (COPD) and Chronic mucus hypersecretion (CMH) pathogenesis.
    Type: Application
    Filed: October 30, 2019
    Publication date: July 2, 2020
    Applicant: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES
    Inventors: HITENDRA S. CHAND, MADHAVAN NAIR
  • Human kunitz-type inhibitor with enhanced antifibrinolytic activity
    Patent number: 7910550
    Abstract: A human Kunitz-type inhibitor polypeptide with enhanced antifibrinolytic activity, methods of making, and methods of use. The novel polypeptide is structurally similar to the KD1 domain of human tissue factor pathway inhibitor-2 (TFPI-2). In another aspect, methods of treating a subject afflicted with cancer or a precancerous condition are described. Generally, the method includes administering to a subject in need of treatment an effective amount of a polypeptide. In some embodiments, the polypeptide comprises a KD1 domain of human TFPI-2. In some embodiments, the polypeptide comprises human TFPI-2, itself. In certain embodiments, the polypeptide is administered in an amount effective to induce apoptosis in tumor cells.
    Type: Grant
    Filed: October 3, 2008
    Date of Patent: March 22, 2011
    Assignee: STC.UNM
    Inventors: Walter Kisiel, Hitendra S. Chand
  • HUMAN KUNITZ-TYPE INHIBITOR WITH ENHANCED ANTIFIBRINOLYTIC ACTIVITY
    Publication number: 20100227808
    Abstract: A human Kunitz-type inhibitor polypeptide with enhanced antifibrinolytic activity, methods of making, and methods of use. The novel polypeptide is structurally similar to the KD1 domain of human tissue factor pathway inhibitor-2 (TFPI-2).
    Type: Application
    Filed: November 12, 2008
    Publication date: September 9, 2010
    Applicant: STC.UNM
    Inventors: Walter Kisiel, Hitendra S. Chand
  • Human kunitz-type inhibitor with enhanced antifibrinolytic activity
    Patent number: 7585842
    Abstract: A human Kunitz-type inhibitor polypeptide with enhanced antifibrinolytic activity, methods of making, and methods of use. The novel polypeptide is structurally similar to the KD1 domain of human tissue factor pathway inhibitor-2 (TFPI-2).
    Type: Grant
    Filed: December 28, 2006
    Date of Patent: September 8, 2009
    Assignee: The Reagents of the University of California
    Inventors: Walter Kisiel, Hitendra S. Chand, S. Paul Bajaj
  • Human kunitz-type inhibitor with enhanced antifibrinolytic activity
    Publication number: 20090099087
    Abstract: A human Kunitz-type inhibitor polypeptide with enhanced antifibrinolytic activity, methods of making, and methods of use. The novel polypeptide is structurally similar to the KD1 domain of human tissue factor pathway inhibitor-2 (TFPI-2). In another aspect, methods of treating a subject afflicted with cancer or a precancerous condition are described. Generally, the method includes administering to a subject in need of treatment an effective amount of a polypeptide. In some embodiments, the polypeptide comprises a KD1 domain of human TFPI-2. In some embodiments, the polypeptide comprises human TFPI-2, itself. In certain embodiments, the polypeptide is administered in an amount effective to induce apoptosis in tumor cells.
    Type: Application
    Filed: October 3, 2008
    Publication date: April 16, 2009
    Applicant: STC.UNM
    Inventors: Walter Kisiel, Hitendra S. Chand
  • Human Kunitz-type inhibitor with enhanced antifibrinolytic activity
    Patent number: 7432238
    Abstract: A human Kunitz-type inhibitor polypeptide with enhanced antifibrinolytic activity, methods of making, and methods of use. The novel polypeptide is structurally similar to the KD1 domain of human tissue factor pathway inhibitor-2 (TFPI-2).
    Type: Grant
    Filed: April 15, 2005
    Date of Patent: October 7, 2008
    Assignee: STC.UNM
    Inventors: Walter Kisiel, Hitendra S. Chand